Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer
Published 2015 View Full Article
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Title
Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer
Authors
Keywords
Breast cancer, FinHer, HER2, Phosphorylated STAT3, Randomised trial, Trastuzumab resistance
Journal
BMC Medicine
Volume 13, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-08-01
DOI
10.1186/s12916-015-0416-2
References
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Related references
Note: Only part of the references are listed.- Feedback activation of STAT3 mediates trastuzumab resistance via upregulation of MUC1 and MUC4 expression
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- (2014) Hatice U. Osmanbeyoglu et al. GENOME RESEARCH
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- (2014) R. W. Tell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer
- (2013) Amir Sonnenblick et al. BREAST CANCER RESEARCH AND TREATMENT
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis
- (2012) Amir Sonnenblick et al. Clinical & Translational Oncology
- Characterization and Clinical Evaluation of CD10+ Stroma Cells in the Breast Cancer Microenvironment
- (2012) C. Desmedt et al. CLINICAL CANCER RESEARCH
- Gene Modules and Response to Neoadjuvant Chemotherapy in Breast Cancer Subtypes: A Pooled Analysis
- (2012) Michail Ignatiadis et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies
- (2012) Pasquale Sansone et al. JOURNAL OF CLINICAL ONCOLOGY
- Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population
- (2012) Hasan Korkaya et al. MOLECULAR CELL
- Erratum: Integrated genomic analyses of ovarian carcinoma
- (2012) The Cancer Genome Atlas Research Network NATURE
- Adjuvant Trastuzumab in HER2-Positive Breast Cancer
- (2011) Dennis Slamon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Stat3 Mediates Expression of Autotaxin in Breast Cancer
- (2011) Janeen Azare et al. PLoS One
- A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
- (2009) Pierre Farmer et al. NATURE MEDICINE
- Stromal gene expression predicts clinical outcome in breast cancer
- (2008) Greg Finak et al. NATURE MEDICINE
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