Article
Clinical Neurology
Wei Lin, Bo Wu, Bin Chen, Guiying Lai, Shengbin Huang, Shaoli Li, Kefu Liu, Chuyan Zhong, Weikang Huang, Shixin Yuan, Yueyun Wang
Summary: Our study revealed a significant proportion of pregnant women in Shenzhen exhibited mild anxiety and depression symptoms during the COVID-19 epidemic. Poor sleep conditions were strongly associated with anxious and depressive symptoms, including random or late bedtime, difficulty falling asleep, short sleep duration, and ordinary or poor subjective sleep quality.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Chiara Penengo, Chiara Colli, Maddalena Cesco, Veronica Croccia, Matilde Degano, Alessandra Ferreghini, Marco Garzitto, Marci Lobel, Heidi Preis, Alessia Sala, Lorenza Driul, Matteo Balestrieri
Summary: This study aimed to evaluate the association between anxiety, depressive and obsessive-compulsive symptomatology in Italian women during the second wave of the COVID-19 pandemic and pregnancy-specific stress, pandemic-related stress, and coping strategies.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Obstetrics & Gynecology
Ayik Batuhan, Yilmaz Salih
Summary: This study aimed to determine the correlations between psychiatric symptoms and attitudes towards vaccination in pregnant women. The findings showed a significant correlation between obsessive-compulsive symptoms and negative attitudes towards vaccination. Therefore, it is crucial to screen pregnant women with lower vaccination rates for psychiatric symptoms.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Psychiatry
Anna Feeney, Rebecca S. Hock, Heather A. Harmon, Phoebe S. Caplin, Lauren A. Kobylski, Adele C. Viguera, Marlene P. Freeman, Lee S. Cohen
Summary: The study found that the COVID-19 pandemic had a negative impact on the pregnancy, delivery, and postpartum experiences of women with histories of psychiatric disorders, particularly in terms of changes in care and perceived social support.
GENERAL HOSPITAL PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Jennifer L. Ames, Assiamira Ferrara, Lyndsay A. Avalos, Sylvia E. Badon, Mara B. Greenberg, Monique M. Hedderson, Michael W. Kuzniewicz, Yinge Qian, Kelly C. Young-Wolff, Ousseny Zerbo, Yeyi Zhu, Lisa A. Croen
Summary: Research indicates that the prevalence of COVID-19 among reproductive-aged women is influenced by social and health disparities, with Hispanic women and those affected by pandemic-related job loss being more susceptible to the virus, while underlying comorbidities do not show a significant impact.
Article
Immunology
Patricia Zadorosnei Rebutini, Aline Cristina Zanchettin, Emanuele Therezinha Schueda Stonoga, Daniele Margarita Marani Pra, Andre Luiz Parmegiani de Oliveira, Felipe da Silva Deziderio, Aline Simoneti Fonseca, Julio Cesar Honorio Dagostini, Elisa Carolina Hlatchuk, Isabella Naomi Furuie, Jessica da Silva Longo, Barbara Maria Cavalli, Carolina Lumi Tanaka Dino, Viviane Maria de Carvalho Hessel Dias, Ana Paula Percicote, Meri Bordignon Nogueira, Sonia Mara Raboni, Newton Sergio de Carvalho, Cleber Machado-Souza, Lucia de Noronha
Summary: This study compared the placental morphological and morphometric changes in pregnant women infected with SARS-CoV-2 with those of non-infected pregnant women. The results showed that symptomatic women in the COVID-19 group were more likely to have adverse fetal outcomes, with more frequent histopathologic findings of maternal and fetal vascular malperfusion. There were no significant differences in morphometric changes between the COVID-19 group and the Control group, except for slightly more accentuated deposition of villous fibrin in the COVID-19 group.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Microbiology
Dominique E. Werter, Heleen J. Schuster, Caroline Schneeberger, Eva Pajkrt, Christianne J. M. de Groot, Elisabeth van Leeuwen, Brenda M. Kazemier
Summary: This study investigated the change in prevalence of infections in pregnancy during the COVID-19 pandemic. The results showed a significant decrease in GBS-carriage during the first lockdown, but no significant differences during the second lockdown. There was a trend towards an increase in Cytomegalovirus infection during the inter-lockdown period. Further research is needed to confirm these findings.
Article
Medicine, General & Internal
Agnieszka Wikarek, Agnieszka Niemiec, Malgorzata Szymanek, Mateusz Klimek, Justyna Partyka-Lasota, Kamila Dudzik, Tomasz Wikarek, Krzysztof Nowosielski
Summary: The study examined the impact of the COVID-19 pandemic on the mental health of pregnant and postpartum women, revealing higher levels of depression and anxiety among pregnant women during the pandemic. This highlights the significant effect of the pandemic on women's mental health and the importance of improving mental health support for pregnant women in Poland.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychiatry
Matilde M. Vaghi, McKenzie P. Hagen, Henry M. Jones, Jeanette A. Mumford, Patrick G. Bissett, Russell A. Poldrack
Summary: This study examined the relationship between self-regulation changes and transdiagnostic dimensions of psychopathology in the early phase of the COVID-19 pandemic. The results revealed independent relationships between psychopathology dimensions and longitudinal alterations in specific domains of self-regulation. Symptoms related to anxiety and depression were associated with more cautious decision-making, while social withdrawal was associated with faster non-decision processes. Self-reported measures of self-regulation predicted changes in psychiatric symptoms, highlighting the relevance of psychological dimensions in separate transdiagnostic dimensions of psychiatry.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychiatry
Hai-Xin Bo, Yuan Yang, Jie Chen, Meng Zhang, Yilin Li, Dong-Ying Zhang, Ying Li, Rui Li, Teris Cheung, Chee H. Ng, Xin-Juan Wu, Yu-Tao Xiang
Summary: The COVID-19 pandemic has been linked to increased risk of mental health problems among pregnant and postnatal Chinese women, with over a quarter of them experiencing depression during this time. Factors such as worrying about infection and delaying medical checkups were associated with higher risk of depression, while women living in northern and southeastern parts of China were less likely to experience depression compared to those in central and western regions.
PSYCHOSOMATIC MEDICINE
(2021)
Article
Psychiatry
Hai-Xin Bo, Yuan Yang, Jie Chen, Meng Zhang, Yilin Li, Dong-Ying Zhang, Ying Li, Rui Li, Teris Cheung, Chee H. Ng, Xin-Juan Wu, Yu-Tao Xiang
Summary: The study found a high prevalence of depression (27.43%) among pregnant and postpartum women in China during the COVID-19 pandemic. Women who were worried about COVID-19 infection and had delayed medical checkups were at higher risk of depression. Conversely, women living in northern and southeastern parts of China were less likely to have depression compared to those in central and western parts.
PSYCHOSOMATIC MEDICINE
(2021)
Article
Psychiatry
Min Liu, Nan Li, Xianghao Cai, Xiaoyan Feng, Rong Wang, Peng Xiong
Summary: Pregnant healthcare workers were more likely to experience psychological symptoms such as somatization, anxiety disorders, and hostility during the early stages of the COVID-19 pandemic compared to pregnant non-healthcare workers. Targeted psychological interventions are crucial for pregnant women, especially for those working in healthcare settings, to cope with distress caused by emerging infectious diseases.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Hongguang Chen, Yusong Zou, Hui Shi, Hongyan Ma, Wenyang Huang, Shuzhen Wang, Junli Lu
Summary: This study found that during the COVID-19 pandemic, pregnant women had a higher prevalence of psychological symptoms, which were associated with psychological resilience and attitudes towards the pandemic. The response of pregnant women to COVID-19 indirectly influenced their psychological symptoms through the mediating effect of maternal concerns.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Elodie Pongan, Isabelle Rouch, Mathieu Herrmann, Catherine Perrot, Cecile Lebrun-Givois, Laurie Spirli, Chloe Briollet, Helene Saint Martin, Bernard Laurent, Romain Bachelet, Hanane El Haouari, Aurelie Buisson, Arlette Edjolo, Jean-Michel Dorey
Summary: During the COVID-19 pandemic, older patients with psychiatric disorders had higher levels of anxiety, which was associated with coping strategies, personality traits, and living conditions.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Hong Mei, Na Li, Junwei Li, Dan Zhang, Zhongqiang Cao, Yongjie Zhou, Jiangxia Cao, Ai'fen Zhou
Summary: This study evaluates depression, anxiety, and stress symptoms in pregnant women before and during the COVID-19 pandemic. The research found that pregnant women had higher depression rates but lower stress risks during the pandemic. Pre-pregnant obesity and high educational levels may reduce the risks of depression, anxiety, and stress among pregnant women.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Clinical Neurology
Rongrong Zhu, Dongmei Wang, Huixia Zhou, Wenjia Wang, Shuochi Wei, Dachun Chen, Meihong Xiu, Li Wang, Xiang-Yang Zhang
Summary: This study found that insomnia is more prevalent in female patients with chronic schizophrenia than in male patients, and there are sex differences in the clinical correlates of insomnia. These findings suggest that sex differences should be considered in the prevention and treatment strategies for coexisting insomnia in schizophrenia patients.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Dianying Liu, Shaohua Liu, Hongdong Deng, Lijuan Qiu, Baiyun Xia, Wanglin Liu, Delong Zhang, Dan Huang, Huiyun Guo, Xiangyang Zhang
Summary: The incidence of suicide attempts is higher in Chinese adolescent patients with mood disorders (MD), with a higher percentage among females. Suicide attempters have higher scores on depression-related measures, rumination, and reflective pondering. Gender and rumination are independently associated with suicide attempts, and rumination plays a fully mediating role between depression and suicide attempts.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Yuling Li, Yuan Wang, Xin Guan, Jingyan Yue, Hanjing Emily Wu, Shiqian Zhen, Shu-Chang He, Xiang-Yang Zhang
Summary: This study examined the effects of oxytocin receptor gene (OXTR) polymorphisms on sleep quality. The results revealed that OXTR polymorphisms interacted with each other and influenced daytime dysfunction and personal distress. Gender and age were also associated with empathy traits and sleep quality.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychiatry
Huixia Zhou, Dongmei Wang, Bo Cao, Xiangyang Zhang
Summary: A study found that cortical thickness is generally thinner in drug-naive Chinese Han patients with schizophrenia compared to healthy controls, and it is associated with clinical symptoms.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE
(2023)
Article
Clinical Neurology
Yanan Zhou, Pu Peng, Ning Yuan, Yifan Xiong, Yinli Luo, Lini Liu, Rongrong Tan, Wei Nie, Yuan Wang, Xiangyang Zhang
Summary: Suicidal ideation (SI) is common among people with schizophrenia, but it has received less attention than suicide attempts (SA), particularly in the Chinese population. Alexithymia is a well-established risk factor for SI, yet there have been few studies evaluating their relationship in schizophrenia patients. This study aimed to determine the prevalence and clinical correlates of SI and its relationship with alexithymia in Chinese chronic schizophrenia inpatients.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Deyang Li, Dongmei Wang, Yang Tian, Jiajing Chen, Rongrong Zhu, Yuqing Li, Li Wang, Xiang-Yang Zhang
Summary: This study aimed to explore the relationship between drug craving and aggression in male patients with methamphetamine use disorder (MAUD) with and without depressive symptoms. The results showed that patients with depressive symptoms had higher levels of drug craving and aggression compared to those without depressive symptoms.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Psychiatry
Pu Peng, Dongmei Wang, Qianjin Wang, Yanan Zhou, Yuzhu Hao, Shubao Chen, Qiuxia Wu, Tieqiao Liu, Xiangyang Zhang
Summary: This study aimed to determine the prevalence of alexithymia and its association with sociocultural characteristics, clinical symptoms, neurocognition, and empathy in Chinese patients with schizophrenia. Results showed that approximately one-third of patients had alexithymia, and it was strongly associated with clinical symptoms, neurocognition, and empathy. Therefore, timely screening and intervention for alexithymia in patients with schizophrenia are essential.
ASIA-PACIFIC PSYCHIATRY
(2023)
Article
Clinical Neurology
ZhaoXuan Shang, XiaoE Lang, Jikun Wang, XiangYang Zhang
Summary: This study investigates the relationship between psychotic symptoms and suicide attempts in young first-episode, drug-naive Chinese Han outpatients diagnosed with Major Depressive Disorder (MDD). The prevalence of Psychotic Major Depressive Disorder (PMD) was found to be 8.3% among the enrolled MDD patients. The study assessed 1289 participants using various scales to evaluate the severity of clinical symptoms, and examined thyroid hormone and glucolipid metabolism indicators. The findings indicate that recent suicide attempts were significantly associated with higher HAMA and CGI scores, elevated TSH and TC levels, as well as higher blood pressure.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Neurosciences
Dong-Mei Wang, Da-Chun Chen, Mei-Hong Xiu, Li Wang, Thomas R. Kosten, Xiang-Yang Zhang
Summary: This study suggests that COX2 inhibitors may be promising therapeutics for improving clinical symptoms in first episode schizophrenia patients, but do not have significant effects on cognitive deficits. The rs5275 polymorphism in the COX2 gene is associated with schizophrenia and positive symptoms.
NEUROPSYCHOPHARMACOLOGY
(2023)
Review
Psychiatry
Yang Tian, Huixia Zhou, Dongmei Wang, Xiangyang Zhang
Summary: The study aims to explore the relationship between obesity, alexithymia, and clinical symptoms in patients with chronic schizophrenia. The results show that obese patients scored higher on positive symptoms, difficulty identifying feelings, and difficulty describing feelings. Further analysis reveals that this association is only present in obese schizophrenia patients.
PSYCHIATRY INVESTIGATION
(2023)
Article
Neurosciences
Xiao Huang, Yuan Sun, Anshi Wu, Xiangyang Zhang
Summary: People with schizophrenia have a higher likelihood of being obese or overweight. This study examined the incidence of overweight and obesity, clinical characteristics, and cognitive performance of Chinese Han patients with chronic schizophrenia who were overweight or obese. The findings showed that overweight and obesity were associated with younger age, lower education level, diabetes, and higher PANSP score among patients with schizophrenia.
Article
Neurosciences
Yuchen Li, Ruichenxi Luo, Dongmei Wang, Xiangyang Zhang
Summary: This study investigates the potential relationships between clinical symptoms and empathy in schizophrenia patients and compares the differences between overweight and non-overweight patients. The findings show that overweight patients have distinct clinical characteristics, particularly in terms of empathy, compared with non-overweight patients. Furthermore, different variables are associated with empathy in different groups.
Article
Psychology, Clinical
Mengqian Qu, Dong Mei Wang, Yang Tian, Jiajing Chen, Rongrong Zhu, Yuqing Li, Xiang-Yang Zhang
Summary: This study examines the relationship between childhood maltreatment, social support, and depressive symptoms in methamphetamine-dependent patients, finding that social support plays a significant role in mediating the link between childhood maltreatment and depression.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Article
Psychiatry
Rui-Chen-Xi Luo, Dongmei Wang, Huixia Zhou, Xiao E. Lang, Xiang-Yang Zhang
Summary: Anxiety symptoms are common in Chinese young adult patients with first-episode and drug-naive major depressive disorder. Patients with anxiety symptoms are more likely to have psychotic symptoms, suicide attempts, and more severe depressive symptoms. Suicide attempts in young adult patients with first-episode and drug-naive major depressive disorder are associated with anxiety symptoms, highlighting the importance of reducing anxiety symptoms to prevent suicides.
EARLY INTERVENTION IN PSYCHIATRY
(2023)
Article
Clinical Neurology
Pu Peng, Dongmei Wang, Qianjin Wang, Yanan Zhou, Yuzhu Hao, Shubao Chen, Qiuxia Wu, Tieqiao Liu, Xiangyang Zhang
Summary: Emerging studies suggest that oxidative stress may be involved in deficit syndrome in patients with schizophrenia. Homocysteine, a marker of oxidative stress, is closely associated with schizophrenia. This study found a high incidence of hyperhomocysteinemia and deficit syndrome in patients with schizophrenia. Age, homocysteine levels, and psychiatric symptoms were independently associated with deficit syndrome. Regular monitoring of homocysteine is important for early detection of deficit syndrome in patients with schizophrenia.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)