Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 41, Issue -, Pages 1-7Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2016.07.005
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Funding
- NIH [NS083319, MH060605]
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The crustacean stomatogastric nervous system is a long-standing test bed for studies of circuit dynamics and neuromodulation. We give a brief update on the most recent work on this system, with an emphasis on the broader implications for understanding neural circuits. In particular, we focus on new findings underlining that different levels of dynamics taking place at different time scales all interact in multiple ways. Dynamics due to synaptic and intrinsic neuronal properties, neuromodulation, and long-term gene expression dependent regulation are not independent, but influence each other. Extensive research on the stomatogastric system shows that these dynamic interactions convey robustness to circuit operation, while facilitating the flexibility of producing multiple circuit outputs.
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