Article
Agronomy
Hafiz Muhammad Jhanzab, Abdul Qayyum, Yamin Bibi, Ahmad Sher, Malik Tahir Hayat, Javed Iqbal, Maqsood Qamar, Basem H. Elesawy, Khadiga Ahmed Ismail, Amal F. Gharib, Ahmad El Askary
Summary: The application of nanotechnology in agriculture, specifically in plant growth, slow-release fertilizers, and targeted delivery of agrochemicals, is gaining significance. This study explored the potential effects of nanoparticles mixed with organic chemicals on wheat growth and physiochemical properties. The results showed that the application of chemo-blended nanoparticles promoted wheat growth and development, as well as improved its physiochemical properties.
Article
Chemistry, Physical
Tariq Munir, Arslan Mahmood, Nigum Peter, Noman Rafaqat, Muhammad Imran, H. Elhosiny Ali
Summary: This study synthesized silver-doped silicon dioxide nanoparticles (Ag@SiO2NPs) using the sol-gel method and investigated their physicochemical and biological properties. XRD analysis revealed a phase change from amorphous to face-centered cubic in Ag@SiO2NPs with a crystallite size of 35 to 39 nm. SEM images showed an irregular and nonuniform surface morphology of Ag@SiO2NPs. EDX analysis confirmed the presence of oxygen, silicon, and silver in Ag-doped SiO2NPs. UV-VIS spectroscopy detected an absorbance maximum at 238 nm in the UV region. FTIR analysis revealed different vibrational modes indicating the presence of Si-O-Si, OH, and Si-H-O groups on the surface of NPs. Antibacterial and anticancer activities were evaluated against E.coli and HepG2 cancer cell line, showing maximum inhibition zone of 12 mm and a significant decrease in cell viability (P = 0.025) of 44.24% at 40 mg/mL of Ag@SiO2NPs. Overall, the results demonstrate that increasing the amount of Ag@SiO2NPs enhances their antibacterial and anticancer activities.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Physical
Yang Wu, Sheng Yang, Feiya Fu, Jingjing Zhang, Jianhua Li, Tingfang Ma, Xiangdong Liu, Juming Yao
Summary: By modifying the Cys-CO fabric, a novel composite material with Cys-modified CO fabric decorated with Ag nanoparticles and TA was successfully prepared. Comparative experiments showed that the antibacterial activity of Ag NPs was enhanced after loading TA, while the cytotoxicity of TA was reduced.
APPLIED SURFACE SCIENCE
(2022)
Article
Multidisciplinary Sciences
N. F. Alotaibi, I. H. Alsohaimi, A. M. Hassan, Modather. F. Hussein, Ahmed E. Taha, Nawaf Bin Darwish, A. M. Nassar
Summary: The synthesis of nanostructured cyclopalladated complex and its nanosilver composite was reported for the first time. The compounds were characterized using spectroscopic and morphological analysis, showing good stability and antimicrobial activity.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Nouf M. Al-Enazi, Khawla Alsamhary, Mansour Kha, Fuad Ameen
Summary: The synthesis of pure and Ag and Ce dual-doped ZnO NPs was achieved through a green and facile method, and their cytotoxicity in breast cancer cells and normal cells was studied. The nanoparticles exhibited a hexagonal structure, spherical shape, and smooth surfaces, with Ag and Ce evenly distributed in ZnO. Cytotoxicity experiments showed that the dual-doped NPs had a significantly greater impact on breast cancer cells compared to pure NPs, while both types had no effect on normal cells. Additionally, the antimicrobial activity against harmful bacteria was investigated.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Hasnain Jan, Gouhar Zaman, Hazrat Usman, Rotaba Ansir, Samantha Drouet, Nathalie Gigliolo-Guivarc'h, Christophe Hano, Bilal Haider Abbasi
Summary: Aquilegia pubiflora leaves have been used to treat various diseases and the silver nanoparticles synthesized with its extract show multiple biological activities, including antimicrobial, antioxidant, anti-Alzheimer, anti-diabetic, and anti-cancer effects.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Engineering, Electrical & Electronic
Tejovathi Gudipati, M. Burhanuz Zaman, Shubhlukshmi Kumari, Monika Sharma, Pragya Singh Pawaiya, Rajaram Poolla
Summary: In this study, Ag and AgO nanostructures were successfully synthesized using tamarind fruit extracts, with the ripeness of the fruit and the pH of the precursor solution found to significantly impact the growth and properties of the nanostructures. Metabolite content in the extract was identified as a key factor in controlling the structure and morphology of the nanostructures.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2022)
Article
Biology
Megumi Asada-Utsugi, Kengo Uemura, Takashi Ayaki, Maiko T. Uemura, Sumio Minamiyama, Ryota Hikiami, Toshifumi Morimura, Akemi Shodai, Takatoshi Ueki, Ryosuke Takahashi, Ayae Kinoshita, Makoto Urushitani
Summary: Phosphorylated tau protein accumulates at DNA double-strand breaks (DSBs) in neurons, and failure of DSB repair leads to increased tau pathology, potentially associated with Alzheimer's disease.
COMMUNICATIONS BIOLOGY
(2022)
Article
Oncology
Faraz Chamani, Marla M. Pyle, Tej B. Shrestha, Jan Sebek, Stefan H. Bossmann, Matthew T. Basel, Rahul A. Sheth, Punit Prakash
Summary: This study evaluated the thermal injury to pancreatic cancer cells in vitro and established predictive models for the extent of heat-induced damage. The Arrhenius model with time delay showed the most accurate prediction, and pancreatic cancer cells exhibited higher resistance to hyperthermia treatments. These findings are important for the investigation of thermal therapies as part of pancreatic cancer treatment strategies and the design of treatment planning strategies.
Article
Geriatrics & Gerontology
Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Riccardo Pizzo, Sara Alvente, Chiara Berteotti, Leonardo Lupori, Giulia Sagona, Giuseppe Galvani, Antonia Gurgone, Alessandra Raspanti, Giorgio Medici, Marianna Tassinari, Stefania Trazzi, Elisa Ren, Roberto Rimondini, Tommaso Pizzorusso, Giovanna Zoccoli, Maurizio Giustetto, Elisabetta Ciani
Summary: CDD is a severe neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene, characterized by early-onset epilepsy, intellectual disability, motor impairment, and autistic-like features. The decline in behaviors in older Cdk15 KO mice was associated with decreased neuronal survival, but not worsened neuroanatomical alterations. Evidence was found that CDKL5 may play a fundamental role in neuronal survival during brain aging, suggesting a possible worsening with age of the clinical picture in CDD patients.
Article
Chemistry, Multidisciplinary
Shaimaa Hussein, Ayman M. Mahmoud, Hassan A. Elgebaly, Omnia Magdy Hendawy, Emad H. M. Hassanein, Shaima M. N. Moustafa, Nasser F. Alotaibi, Amr M. Nassar
Summary: In this study, the aqueous extract of garlic tunicate leaf was used to synthesize ruthenium/silver/palladium trimetallic nanocomposites (Ru/Ag/Pd)-Np. Various physicochemical tools were employed to characterize the nanocomposites, and the results showed potent antimicrobial and antiproliferative activities of (Ru/Ag/Pd)-Np. The antiproliferative potential of (Ru/Ag/Pd)-Np was significantly enhanced by UV irradiation.
JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Soha A. Hassan, Marwa Beleidy, Yasmine Alaa El-din
Summary: The study aimed to investigate the biocompatibility and sustainability differences between two computer-aided design/computer-aided manufacturing resin-based composites and a resin-modified ceramic. The results showed no significant differences in surface roughness and biofilm formation, with the EN material showing the lowest cytotoxicity and highest viability, while BC material exhibited the highest biofilm formation capacity.
Article
Multidisciplinary Sciences
Govindan Nadar Rajivgandhi, Gnansekaran Chackaravarthi, Govindan Ramachandran, Chenthis Kanisha Chelliah, Muthuchamy Maruthupandy, Mohammed S. Alharbi, Naiyf S. Alharbi, Jamal M. Khaled, Wen-Jun Li
Summary: In this study, the excellent anti-cancer activity of silver nanoparticles against MCF-7 breast cancer cells was demonstrated. The nanoparticles induced cytotoxicity, morphological changes, and damage to intracellular structures.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Zuzana Knazicka, Hana Duranova, Veronika Fialkova, Michal Miskeje, Tomas Jambor, Alexander V. Makarevich, Shubhadeep Roychoudhury, Anton Kovacik, Peter Massanyi, Norbert Lukac
Summary: The study assessed the in vitro effects of ferrous sulphate on bovine spermatozoa in a dose- and time-dependent manner. Results indicated that high concentrations of FeSO4.7H(2)O had toxic effects on spermatozoa structure and function, while low concentrations may enhance fertilization potential.
Article
Nanoscience & Nanotechnology
K. R. Aranganayagam, R. Marudhachalam
Summary: Zinc oxide (ZnO) and Ag-doped ZnO nanoparticles were synthesized and characterized using various techniques. Ag doping resulted in the formation of nanorods with decreased grain size. The synthesized materials showed antimicrobial properties and higher cytotoxicity against cancer cells compared to pure ZnO. Additionally, the samples exhibited catalytic activity and a statistical model was developed for antibacterial studies.
Article
Materials Science, Multidisciplinary
Umar Nishan, Sajida Rehman, Riaz Ullah, Ahmed Bari, Saifullah Afridi, Mohibullah Shah, Jibran Iqbal, Muhammad Asad, Amir Badshah, Naeem Khan, In Min Hwang, Hameed Ullah Khan, Nawshad Muhammad
Summary: Nitrites and nitrates, commonly used in cured meat products, can be harmful to health. A new approach using drug-mediated CuO NPs synthesis allows for simple colorimetric detection of nitrites in processed food, with a linear range of 1 x 10(-8) to 2.40 x 10(-6) M. This sensor has potential applications in on-site analysis, disease diagnosis, environmental monitoring, and food safety.
FRONTIERS IN MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Omer I. I. Fantoukh, Gadah A. A. Al-Hamoud, Fahd A. A. Nasr, Omer M. M. Almarfadi, Mohammed F. F. Hawwal, Zulfiqar Ali, Waleed A. A. Alobaid, Abdulaziz Binawad, Menwer Alrashidi, Fawaz Alasmari, Mohammad Z. Z. Ahmed, Omar M. M. Noman
Summary: In this study, four secondary metabolites were isolated and characterized from the methanolic extract of Euphorbia saudiarabica. The CHCl3 and EtOAc fractions of E. saudiarabica inhibited the proliferation of cancer cells and induced apoptosis. Additionally, glutinol showed potent activity against the MCF-7 cell line.
Article
Multidisciplinary Sciences
Govindan Rajivgandhi, Shine Kadaikunnan, Govindan Ramachandran, Gnansekaran Chackaravarthi, Chenthis Kanisha Chelliah, Muthuchamy Maruthupandy, Manoharan Natesan, Franck Quero, Wen-Jun Li
Summary: According to recent research, chitosan, a natural polysaccharide rich biopolymer, is an important carrier molecule for drug loading. Plant essential oils are also frequently used to treat infectious diseases. The study focused on encapsulating plant essential oils into chitosan nanoparticles to inhibit A549 human lung cancer cells. The results showed that chitosan had a unique and uniform size morphology, and the chitosan loaded essential oils at 1000 lg/mL concentration were more effective in damaging the cancer cells compared to chitosan or essential oils alone.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Neurosciences
Faizan Ul Haq, Mohammad Shoaib, Syed Wadood Ali Shah, Haya Hussain, Muhammad Zahoor, Riaz Ullah, Ahmed Bari, Amal Alotaibi, Muhammad Faisal Hayat
Summary: This study aimed to synthesize benzodiazepine derivatives and evaluate their antidepressant potentials. The results showed that compounds 2 and 5 exhibited significant antidepressant effects and increased GABA levels in the brain's hippocampus of experimental animals, indicating the possible involvement of the GABAergic mechanism.
Article
Chemistry, Multidisciplinary
Silviya Mollova, Anatoli Dzhurmanski, Hafize Fidan, Dimitar Bojilov, Stanimir Manolov, Ivayla Dincheva, Stanko Stankov, Albena Stoyanova, Sezai Ercisli, Amine Assouguem, Romina Alina Marc, Riaz Ullah, Ahmed Bari
Summary: This study evaluated the agrobiological characteristics of Nepeta transcaucasica and Nepeta cataria cultivated in Bulgaria, and determined their essential oil composition, antimicrobial activity, and antioxidant activity. The results showed high variability in the population of N. transcaucasica and comparative homogeneity in N. cataria. The essential oils showed antimicrobial activity against E. coli and exhibited high antioxidant activity.
Article
Biochemistry & Molecular Biology
Mubashir Ahmad, Shahzeb Khan, Syed Muhammad Hassan Shah, Muhammad Zahoor, Zahid Hussain, Haya Hussain, Syed Wadood Ali Shah, Riaz Ullah, Amal Alotaibi
Summary: Microfluidic technology can produce smart nanoparticles with improved solubility and bioavailability for poorly water-soluble drugs. This study successfully engineered repaglinide nanocrystals using microfluidic technology, demonstrating enhanced anti-diabetic properties and safety profiles.
Article
Multidisciplinary Sciences
Govindan Rajivgandhi, Shine Kadaikunnan, Govindan Ramachandran, Gnanasekaran Chackaravarthi, Chenthis Kanisha Chelliah, Muthuchamy Maruthupandy, Manoharan Natesan, Franck Quero, Wen-Jun Li
Summary: In this study, chitosan loaded plant essential oils (CsEOs) were tested against Pseudomonas aeruginosa, Escherichia coli, K. pneumoniae, and Staphylococci aureus, and their anti-cancer properties were evaluated against A549 lung cancer cells. The results showed significant inhibition of the bacteria by CsEOs and a considerable inhibition of A549 lung cancer cells. The study concluded that CsEOs have excellent anti-bacterial and anti-cancer properties, making them suitable for delivering drugs and bioactive compounds to target sites.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Zulfa Nooreen, Nasir A. Siddiqui, Pranay Wal, Ankita Shukla, Ram Swaroop Verma, Ateeque Ahmad, Sudeep Tandon, Saad Alkahtani, Abdullah A. Alkahtane, Akram Mohammad
Summary: This study investigates the anti-inflammatory potential of Cuscuta reflexa seed essential oil and finds that it effectively reduces inflammation by inhibiting pro-inflammatory cytokines. The chemical analysis reveals the major components of the oil and the in-vitro activity shows no reduction in viable cells.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Shazia Dilbar, Hassan Sher, Hina Ali, Riaz Ullah, Ahmad Ali, Zahid Ullah
Summary: Silver nanoparticles synthesized from medicinally important aqueous plant extracts of Salvia nubicola exhibit strong antibacterial activity against Ralstonia solanacearum, providing an effective alternative to conventional pesticides and reducing economic losses in tomato production.
Article
Multidisciplinary Sciences
Rabia Iqbal, Iqbal Azhar, Muhammad Nasir Iqbal, Irfan Hamid, Muhammad Zahoor, Muhammad Furqan Akhtar, Zafar Alam Mahmood, Riaz Ullah, Amal Alotaibi
Summary: The seeds of barley, cardamom, and chickpea have traditionally been used to manage diabetes. In this study, poly-herbal granules (PHGs) comprising of these three plants were formulated and their antioxidant and antidiabetic potential were evaluated. The results showed that these granules exhibited excellent antioxidant and antidiabetic properties.
Article
Chemistry, Multidisciplinary
Sayyed Ijazul Haq, Muhammad Nisar, Muhammad Zahoor, Muhammad Ikram, Noor Ul Islam, Riaz Ullah, Amal Alotaibi
Summary: Melazaedarach-based silver nanoparticles (MA-AgNPs) were successfully synthesized using ripened fruit extract and confirmed by various characterization techniques. The nanoparticles exhibited antibacterial activity against tested strains, with higher activity than the fruit extract itself. Furthermore, the nanoparticles showed significant antioxidant activities. These findings suggest that the engineered nanoparticles have promising biological activities and could be used in drug designing as antibacterial and antioxidant agents with further exploration in biological systems.
GREEN PROCESSING AND SYNTHESIS
(2023)
Article
Endocrinology & Metabolism
Zaheer Uddin, Muhammad Zahoor, Syed Wadod Ali Shah, Mehreen Ghias, Muhammad Naveed Umar, Riaz Ullah, Essam A. Ali, Mohammad Attaullah, Sher Wali Khan
Summary: The extracts of Teucrium royleanum have therapeutic effects on diabetes by improving biochemical alterations associated with the disease. They can lower blood glucose levels, restore body weight, improve cholesterol and kidney function, and exhibit antioxidant capabilities.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Chemistry, Multidisciplinary
Chand Bibi, Fazal Hadi, Nasir Ali, Muhammad Zahoor, Alam Zeb, Riaz Ullah, Essam A. Ali, Abdul Bari Shah
Summary: A link has been established between cold acclimation and Cd uptake in Spirogyra aequinoctialis. Cold-acclimated plants accumulated higher concentrations of Cd compared to non-acclimated plants. Cold acclimation also resulted in higher concentrations of free proline and total phenolics. The negative effects of Cd on biomass and pigment contents were more pronounced in non-acclimated plants.
Article
Chemistry, Multidisciplinary
Abdelouahid Laftouhi, Noureddine Eloutassi, Elhachmia Ech-Chihbi, Mohammed Kara, Amine Assouguem, Essam A. Ali, Hafize Fidan, Zakia Rais, Abdslam Taleb, Mustapha Beniken, Mustapha Taleb
Summary: This study investigates the behavior of Salvia officinalis under different climatic disturbances and finds that temperature increase and water supply reduction affect the secondary metabolites and mineral composition of the plant.
Article
Microbiology
Asad Ullah Khan, Muhammad Zahoor, Mujaddad Ur Rehman, Muhammad Ikram, Daochen Zhu, Muhammad Naveed Umar, Riaz Ullah, Essam A. Ali
Summary: Dye-polluted wastewater is a serious threat to human, animal, and plant health. To mitigate this, the treatment of wastewater containing dyes is necessary. This study demonstrates the use of Pseudomonas aeruginosa to degrade the textile azo dye brown 703. Optimization experiments showed that under specific conditions, the bacterial strain can effectively decolorize and degrade the dye within 3 days.
MICROBIOLOGY RESEARCH
(2023)