Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function

A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

(2020) Weidong Feng et al.   eLife

Neuronal identity control by terminal selectors in worms, flies, and chordates

(2019) Oliver Hobert et al.   CURRENT OPINION IN NEUROBIOLOGY

Transcription factor autoregulation is required for acquisition and maintenance of neuronal identity

(2019) Eduardo Leyva-Díaz et al.   DEVELOPMENT

Actors with Multiple Roles: Pleiotropic Enhancers and the Paradigm of Enhancer Modularity

(2019) Gonzalo Sabarís et al.   TRENDS IN GENETICS

Transcriptional mechanisms of motor neuron development in vertebrates and invertebrates

(2019) Catarina Catela et al.   DEVELOPMENTAL BIOLOGY

Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features

(2018) Nikolaos Konstantinides et al.   CELL

Early emergence of cortical interneuron diversity in the mouse embryo

(2018) Da Mi et al.   SCIENCE

Developmental diversification of cortical inhibitory interneurons

(2018) Christian Mayer et al.   NATURE

An open-source platform for analyzing and sharing worm-behavior data

(2018) Avelino Javer et al.   NATURE METHODS

Powerful and interpretable behavioural features for quantitative phenotyping of Caenorhabditis elegans

(2018) Avelino Javer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Diversification of C. elegans Motor Neuron Identity via Selective Effector Gene Repression

(2017) Sze Yen Kerk et al.   NEURON

A mouse tissue transcription factor atlas

(2017) Quan Zhou et al.   Nature Communications

An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons

(2017) Paschalis Kratsios et al.   eLife

Pet-1 Switches Transcriptional Targets Postnatally to Regulate Maturation of Serotonin Neuron Excitability

(2016) Steven C. Wyler et al.   JOURNAL OF NEUROSCIENCE

Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers

(2016) Ho Sung Rhee et al.   NEURON

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes

(2016) Catarina Catela et al.   Cell Reports

A map of terminal regulators of neuronal identity in Caenorhabditis elegans

(2016) Oliver Hobert   Wiley Interdisciplinary Reviews-Developmental Biology

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

(2015) Simona Lodato et al.   Annual Review of Cell and Developmental Biology

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Transcriptional Coordination of Synaptogenesis and Neurotransmitter Signaling

(2015) Paschalis Kratsios et al.   CURRENT BIOLOGY

The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans

(2015) L. Zhang et al.   DEVELOPMENT

The function and regulation of the GATA factor ELT-2 in theC. elegansendoderm

(2015) Tobias Wiesenfahrt et al.   DEVELOPMENT

Multi-Scale Molecular Deconstruction of the Serotonin Neuron System

(2015) Benjamin W. Okaty et al.   NEURON

Hox Proteins Act as Transcriptional Guarantors to Ensure Terminal Differentiation

(2015) Chaogu Zheng et al.   Cell Reports

A cellular and regulatory map of the cholinergic nervous system of C. elegans

(2015) Laura Pereira et al.   eLife

The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B

(2015) M. Moris-Sanz et al.   Biology Open

ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

(2014) Li Shen et al.   BMC GENOMICS

Systematic expression analysis of Hox genes at adulthood reveals novel patterns in the central nervous system

(2014) Bertrand Hutlet et al.   Brain Structure & Function

Comparative analysis of regulatory information and circuits across distant species

(2014) Alan P. Boyle et al.   NATURE

Maintenance of postmitotic neuronal cell identity

(2014) Evan S Deneris et al.   NATURE NEUROSCIENCE

Dual role for Hox genes and Hox co-factors in conferring leg motoneuron survival and identity in Drosophila

(2013) M. Baek et al.   DEVELOPMENT

Roles ofHoxgenes in the patterning of the central nervous system ofDrosophila

(2013) Alicia Estacio-Gómez et al.   FLY

Loss of Otx2 in the Adult Retina Disrupts Retinal Pigment Epithelium Function, Causing Photoreceptor Degeneration

(2013) M. Housset et al.   JOURNAL OF NEUROSCIENCE

A database of Caenorhabditis elegans behavioral phenotypes

(2013) Eviatar Yemini et al.   NATURE METHODS

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Hox Genes: Choreographers in Neural Development, Architects of Circuit Organization

(2013) Polyxeni Philippidou et al.   NEURON

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

(2013) B. Kadkhodaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The conserved transcription factor Mef2 has multiple roles in adult Drosophila musculature formation

(2012) C. Soler et al.   DEVELOPMENT

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum

(2012) R. Lopes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Terminal Differentiation Programs in the Nervous System

(2011) Oliver Hobert   Annual Review of Cell and Developmental Biology

Discrete regulatory regions control early and late expression of D-Pax2 during external sensory organ development

(2011) Seth A. Johnson et al.   DEVELOPMENTAL DYNAMICS

Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene

(2011) Paschalis Kratsios et al.   NATURE NEUROSCIENCE

Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins

(2010) N. Treiber et al.   GENES & DEVELOPMENT

CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

(2010) J. C. Corbo et al.   GENOME RESEARCH

Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin

(2010) Thomas Treiber et al.   IMMUNITY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Segment-Specific Neuronal Subtype Specification by the Integration of Anteroposterior and Temporal Cues

(2010) Daniel Karlsson et al.   PLOS BIOLOGY

Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response

(2010) Mei Zhong et al.   PLoS Genetics

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

Gene regulatory logic of dopamine neuron differentiation

(2009) Nuria Flames et al.   NATURE

Neuronal function of Tbx20 conserved from nematodes to vertebrates

(2008) Roger Pocock et al.   DEVELOPMENTAL BIOLOGY

Regulatory logic of neuronal diversity: Terminal selector genes and selector motifs

(2008) O. Hobert   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA