Fumonisin B1 Epigenetically Regulates PTEN Expression and Modulates DNA Damage Checkpoint Regulation in HepG2 Liver Cells

Fusaric acid-induced promoter methylation of DNA methyltransferases triggers DNA hypomethylation in human hepatocellular carcinoma (HepG2) cells

(2019) Terisha Ghazi et al.   Epigenetics

Fumonisins: Impact on Agriculture, Food, and Human Health and their Management Strategies

(2019) Madhu Kamle et al.   Toxins

Genetic toxicity assessment using liver cell models: past, present, and future

(2019) Xiaoqing Guo et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinoma

(2018) Xue-Mei Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways

(2018) Weijun Su et al.   ONCOGENE

Fumonisin B1-induced oxidative stress triggers Nrf2-mediated antioxidant response in human hepatocellular carcinoma (HepG2) cells

(2018) Thilona Arumugam et al.   Mycotoxin Research

Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts

(2016) Nicole M. Gardner et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer

(2016) Shalenie P. den Braver-Sewradj et al.   TOXICOLOGY IN VITRO

PTENInhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERTPathway in Lung Adenocarcinoma A549 Cells

(2016) Xiao-Xiao Lu et al.   Biomed Research International

Role of microRNA-30c in lipid metabolism, adipogenesis, cardiac remodeling and cancer

(2015) Sara Irani et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

(2015) Kirti Shukla et al.   Molecular Oncology

Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells

(2015) Duygu Sancak et al.   TOXICOLOGY IN VITRO

Panax ginseng extract modulates oxidative stress, DNA fragmentation and up-regulate gene expression in rats sub chronically treated with aflatoxin B1 and fumonisin B1

(2014) Aziza M. Hassan et al.   CYTOTECHNOLOGY

Fumonisin B1 modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b

(2014) Anil A. Chuturgoon et al.   TOXICOLOGY LETTERS

KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation

(2014) Benjamin L Kidder et al.   GENOME BIOLOGY

Mycotoxins: Occurrence, toxicology, and exposure assessment

(2013) S. Marin et al.   FOOD AND CHEMICAL TOXICOLOGY

Mycotoxins and their effects on human and animal health

(2013) Maria Edite Bezerra da Rocha et al.   FOOD CONTROL

Effect of fumonisin B1 on the cell cycle of normal human liver cells

(2013) SHAO-KANG WANG et al.   Molecular Medicine Reports

Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

(2013) C. Bassi et al.   SCIENCE

Fumonisin B1 induces global DNA hypomethylation in HepG2 cells – An alternative mechanism of action

(2013) Anil Chuturgoon et al.   TOXICOLOGY

Fumonisin B1 Contamination of Cereals and Risk of Esophageal Cancer in a High Risk Area in Northeastern Iran

(2012) Ali Mohammad Alizadeh et al.   Asian Pacific Journal of Cancer Prevention

PTEN in DNA damage repair

(2012) Mei Ming et al.   CANCER LETTERS

Fumonisin B1 and the kidney: Modes of action for renal tumor formation by fumonisin B1 in rodents

(2012) Stephanie Müller et al.   FOOD AND CHEMICAL TOXICOLOGY

Daily intake estimates of fumonisins in corn-based food products in the population of Parana, Brazil

(2012) Fernanda Andrade Martins et al.   FOOD CONTROL

Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses

(2012) Hélène Pellanda et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells

(2012) Verónica S. Mary et al.   TOXICOLOGY

Fumonisin B1 inhibits mitochondrial respiration and deregulates calcium homeostasis—Implication to mechanism of cell toxicity

(2011) Ana-Marija Domijan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

(2010) Barbara van Loon et al.   DNA REPAIR

Akt Activation Emulates Chk1 Inhibition and Bcl2 Overexpression and Abrogates G2 Cell Cycle Checkpoint by Inhibiting BRCA1 Foci

(2010) Ivana Tonic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTEN in liver diseases and cancer

(2010) Marion Peyrou   WORLD JOURNAL OF GASTROENTEROLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Subchronic mycotoxicoses in Wistar rats: Assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B1, and oxidative stress biomarkers status

(2009) M.G. Theumer et al.   TOXICOLOGY

Hormesis defined

(2007) Mark P. Mattson   AGEING RESEARCH REVIEWS