Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

REVISITING THE CORRELATE OF REDUCED HIV INFECTION RISK IN THE RV144 VACCINE TRIAL

(2019) Susan Zolla-Pazner et al.   JOURNAL OF VIROLOGY

Vaccine-induced V1V2-specific antibodies control and or protect against infection with HIV, SIV and SHIV

(2019) Susan Zolla-Pazner et al.   Current Opinion in HIV and AIDS

ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type

(2019) Luca Schifanella et al.   PLoS Pathogens

Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex

(2018) Zoltan Beck et al.   JOURNAL OF CONTROLLED RELEASE

Liposome-Encapsulated Human Immunodeficiency Virus-1 gp120 Induces Potent V1V2-Specific Antibodies in Humans

(2018) Mangala Rao et al.   JOURNAL OF INFECTIOUS DISEASES

Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques

(2018) Shakti Singh et al.   JOURNAL OF VIROLOGY

Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis

(2018) Rebecca F. Baggaley et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

(2018) Margaret E. Ackerman et al.   NATURE MEDICINE

Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake

(2017) Frank Liang et al.   Science Translational Medicine

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

(2017) Todd Bradley et al.   Nature Communications

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

(2016) M Sips et al.   Mucosal Immunology

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

(2016) Monica Vaccari et al.   NATURE MEDICINE

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

(2015) Amy W. Chung et al.   CELL

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

(2015) Lindsay Wieczorek et al.   JOURNAL OF VIROLOGY

COMPASS identifies T-cell subsets correlated with clinical outcomes

(2015) Lin Lin et al.   NATURE BIOTECHNOLOGY

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

(2015) D. H. Barouch et al.   SCIENCE

Analysis of repeated low-dose challenge studies

(2015) Tracy L. Nolen et al.   STATISTICS IN MEDICINE

Sex-based differences in immune function and responses to vaccination

(2015) S. L. Klein et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Differential immune responses to HIV-1 envelope protein induced by liposomal adjuvant formulations containing monophosphoryl lipid A with or without QS21

(2015) Zoltan Beck et al.   VACCINE

Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at least 4 years after vaccination

(2015) Geert Leroux-Roels et al.   VACCINE

Parsimonious Determination of the Optimal Infectious Dose of a Pathogen for Nonhuman Primate Models

(2015) Mario Roederer   PLoS Pathogens

Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge

(2015) Iskra Tuero et al.   PLoS Pathogens

Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination

(2014) N. L. Yates et al.   Science Translational Medicine

Protective Efficacy of a Global HIV-1 Mosaic Vaccine against Heterologous SHIV Challenges in Rhesus Monkeys

(2013) Dan H. Barouch et al.   CELL

Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

(2013) Raphael Gottardo et al.   PLoS One

17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription

(2013) Erika L. Szotek et al.   VIROLOGY

A Phase 1/2 Clinical Trial Evaluating Safety and Immunogenicity of a Varicella Zoster Glycoprotein E Subunit Vaccine Candidate in Young and Older Adults

(2012) Isabel Leroux-Roels et al.   JOURNAL OF INFECTIOUS DISEASES

Extended Evaluation of the Virologic, Immunologic, and Clinical Course of Volunteers Who Acquired HIV-1 Infection in a Phase III Vaccine Trial of ALVAC-HIV and AIDSVAX B/E

(2012) Supachai Rerks-Ngarm et al.   JOURNAL OF INFECTIOUS DISEASES

Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144

(2012) Merlin L Robb et al.   LANCET INFECTIOUS DISEASES

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

(2012) Dan H. Barouch et al.   NATURE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

(2010) Margaret E. Ackerman et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The Xs and Y of immune responses to viral vaccines

(2010) Sabra L Klein et al.   LANCET INFECTIOUS DISEASES

Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1

(2009) Angela Meier et al.   NATURE MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

(2009) Patricia L. Earl et al.   VACCINE

Correlation of Vaccine-Elicited Systemic and Mucosal Nonneutralizing Antibody Activities with Reduced Acute Viremia following Intrarectal Simian Immunodeficiency Virus SIVmac251 Challenge of Rhesus Macaques

(2008) R. Hidajat et al.   JOURNAL OF VIROLOGY

Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia

(2008) G. D. Tomaras et al.   JOURNAL OF VIROLOGY

The Macaque Gut Microbiome in Health, Lentiviral Infection, and Chronic Enterocolitis

(2008) Philip McKenna et al.   PLoS Pathogens