Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for “polygenic epistasis”

Key molecules in lymphatic development, function, and identification

(2018) Sawan Kumar Jha et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Emerging insights into the role of matrix metalloproteases as therapeutic targets in fibrosis

(2018) Nikolaos A. Afratis et al.   MATRIX BIOLOGY

An ancestry-based approach for detecting interactions

(2017) Danny S. Park et al.   GENETIC EPIDEMIOLOGY

Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice

(2017) Christoph D. Rau et al.   Cell Systems

Are Interactions between cis -Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts?

(2016) Alexandra E. Fish et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Decreased RARβ expression induces abundant inflammation and cervical precancerous lesions

(2016) ME Albino-Sanchez et al.   EXPERIMENTAL CELL RESEARCH

Genetic Background Limits Generalizability of Genotype-Phenotype Relationships

(2016) Laura J. Sittig et al.   NEURON

Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models

(2016) Jae Hoon Sul et al.   PLoS Genetics

Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross

(2016) Anna L. Tyler et al.   PLoS Genetics

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

Meta-analysis of the heritability of human traits based on fifty years of twin studies

(2015) Tinca J C Polderman et al.   NATURE GENETICS

Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures

(2015) Yajie Wang et al.   NUCLEIC ACIDS RESEARCH

Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-Adrenergic Stimulation in MiceCLINICAL PERSPECTIVE

(2014) Christoph D. Rau et al.   Circulation-Cardiovascular Genetics

Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions

(2014) Valerie A. Street et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Why epistasis is important for tackling complex human disease genetics

(2014) Trudy FC Mackay et al.   Genome Medicine

Architecture and function of metallopeptidase catalytic domains

(2013) Núria Cerdà-Costa et al.   PROTEIN SCIENCE

The Alternative Heart: Impact of Alternative Splicing in Heart Disease

(2013) Enrique Lara-Pezzi et al.   Journal of Cardiovascular Translational Research

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

(2012) Anatole Ghazalpour et al.   MAMMALIAN GENOME

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS

Epistasis in sporadic Alzheimer's disease

(2008) Onofre Combarros et al.   NEUROBIOLOGY OF AGING

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics