Article
Nutrition & Dietetics
Yoonjung Park, Young-Mi Ah, Yun Mi Yu
Summary: This study conducted a meta-analysis of randomized controlled trials to investigate the effects of vitamin D supplementation on depressive symptom improvement in individuals aged ≥60 years with or without a diagnosis of depression or depressive symptoms. The results showed that vitamin D supplementation was not significantly associated with an improvement in depressive symptoms.
FRONTIERS IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Yann Nguyen, Johanna Sigaux, Jean-Guillaume Letarouilly, Pauline Sanchez, Sebastien Czernichow, Rene-Marc Flipo, Martin Soubrier, Luca Semerano, Raphaele Seror, Jeremie Sellam, Claire Daien
Summary: Oral vitamin supplementation did not show significant reduction in RA activity, however, folic acid supplementation can prevent methotrexate-related side effects, and vitamin D can prevent musculo-skeletal complications in patients with vitamin D deficiency.
Review
Chemistry, Medicinal
Yasaman Vahedi-Mazdabadi, Hossein Shahinfar, Mohammad Toushih, Farzad Shidfar
Summary: Based on a comprehensive meta-analysis of randomized controlled trials, berberine supplementation has been shown to have a dose-dependent beneficial effect on reducing inflammatory biomarkers such as IL-6, TNF-a, and CRP in adults. However, the findings are limited by low-quality studies and significant heterogeneity, indicating that more investigation and high-quality evidence are needed to obtain comprehensive and generalizable results.
PHYTOTHERAPY RESEARCH
(2023)
Article
Psychiatry
Mina Kaviani, Bahareh Nikooyeh, Farnaz Etesam, Siroos Jahangiri Behnagh, Hamed Mohammadi Kangarani, Mohammad Arefi, Parichehreh Yaghmaei, Tirang R. Neyestani
Summary: This study evaluated the effects of vitamin D supplementation on patients with mild to moderate depression. The results showed that after 8 weeks of supplementation, patients had increased vitamin D levels and decreased depression severity, but these effects were independent of inflammatory biomarkers.
Review
Nutrition & Dietetics
Mohammad Reza Emami, Sanaz Jamshidi, Meysam Zarezadeh, Masoud Khorshidi, Beheshteh Olang, Zohreh Sajadi Hezaveh, Mohammadhassan Sohouli, Naheed Aryaeian
Summary: Vitamin E supplementation showed no significant effect on weight, BMI, and waist circumference overall, but it may increase BMI in individuals with normal BMI.
CLINICAL NUTRITION
(2021)
Review
Food Science & Technology
Fatemeh Hajizadeh-Sharafabad, Elham Sharifi Zahabi, Mahsa Malekahmadi, Rasoul Zarrin, Mohammad Alizadeh
Summary: This study conducted a systematic review and meta-analysis of randomized controlled trials to investigate the effects of carotenoids on inflammatory parameters. The results showed significant effects of carotenoids on C-reactive protein and interleukin-6, but not on tumor necrosis factor-alpha. Individual carotenoids like astaxanthin, lutein/zeaxanthin, and beta-cryptoxanthin significantly decreased CRP levels, while only lycopene led to a significant decrease in IL-6. Overall, carotenoids may have protective effects on inflammatory biomarkers.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Tuomas Mikola, Wolfgang Marx, Melissa M. Lane, Meghan Hockey, Amy Loughman, Sanna Rajapolvi, Tetyana Rocks, Adrienne O'Neil, David Mischoulon, Minna Valkonen-Korhonen, Soili M. Lehto, Anu Ruusunen
Summary: Neurosteroid and immunological actions of vitamin D may regulate depression-linked physiology. Meta-analysis results showed a positive effect of vitamin D on depressive symptoms, although the certainty was very low. Despite high heterogeneity, supplementation of vitamin D at a dose of ≥ 2,000 IU per day appears to reduce depressive symptoms. Future research should investigate the potential benefits of adjunctive vitamin D treatment in clinical depression.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Pharmacology & Pharmacy
Kai-Jie Qi, Zhong-Tao Zhao, Wen Zhang, Fang Yang
Summary: Vitamin D supplementation may benefit adults with metabolic syndrome by reducing insulin resistance and hypertension. However, its effects on blood lipid profile and HbA1c remain inconclusive.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Nutrition & Dietetics
Myunghee Kim, Hyeyoon Eo, Josephine Gahyun Lim, Hyunjung Lim, Yunsook Lim
Summary: This meta-analysis found that dietary vitamin E supplementation can attenuate exercise-induced muscle damage, especially when the supplementation is less than 500 IU.
Review
Clinical Neurology
Jia Fu, Junfang Sun, Chao Zhang
Summary: This meta-analysis investigated the association between vitamin D supplementation and the risk of stroke. The results showed that additional vitamin D supplementation did not reduce the risk of stroke. The study suggests that further randomized controlled trials of similar design should not be encouraged to assess any association between vitamin D supplementation and reduced stroke risk.
FRONTIERS IN NEUROLOGY
(2022)
Review
Nutrition & Dietetics
Tafirenyika Gwenzi, Anna Zhu, Petra Schrotz-King, Ben Schoettker, Michael Hoffmeister, Hermann Brenner
Summary: This systematic review and meta-analysis evaluated the effects of vitamin D3 supplementation on serum inflammatory biomarkers among patients with cancer or pre-cancerous lesions. The study found that vitamin D3 supplementation significantly reduced TNF-a levels and may have a suppressive effect on tumor-promoting inflammatory response in patients with cancer or pre-cancerous lesions.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Nicola Veronese, Damiano Pizzol, Lee Smith, Ligia J. Dominguez, Mario Barbagallo
Summary: Magnesium supplementation may significantly reduce human inflammatory markers, particularly serum CRP and NO levels.
Review
Endocrinology & Metabolism
Marlene Chakhtoura, Dania S. Bacha, Charbel Gharios, Sara Ajjour, Mariam Assaad, Yara Jabbour, Francesca Kahale, Aya Bassatne, Stephanie Antoun, Elie A. Akl, Roger Bouillon, Paul Lips, Peter R. Ebeling, Ghada El-Hajj Fuleihan
Summary: This umbrella review investigated the quality and discrepancies of systematic reviews/meta-analyses on vitamin D supplementation for fracture risk reduction in adults. The results show that vitamin D combined with calcium can reduce the risk of hip and any fractures, potentially driven by findings from institutionalized individuals. However, there are discrepancies in results due to different trial inclusion, search periods, eligibility criteria, and methodologies used. Individual participant data meta-analyses and subgroup analysis are recommended to further explore determinants for a beneficial response to supplementation.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Immunology
Amir Hossein Faghfouri, Ladan Gol Mohammad Pour Afrakoti, Zeynab Kavyani, Zahra Sadeghi Nogourani, Vali Musazadeh, Mahdi Jafarlou, Parvin Dehghan
Summary: This umbrella meta-analysis found that probiotic supplementation significantly reduced serum concentrations of C-reactive protein, TNF-alpha, and interleukin-6. Therefore, probiotic supplementation can be considered as an adjuvant therapy to alleviate inflammation in various inflammatory conditions.
INFLAMMOPHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Fatemeh Dashti, Seyed Mohammad Mousavi, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study analyzed 38 studies and found that vitamin D significantly decreased the serum concentrations of CRP, IL-6, and TNF-alpha in individuals with abnormal glucose homeostasis.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Integrative & Complementary Medicine
Masoume Mansouri, Farshad Sharifi, Mehdi Varmaghani, Hamid Yaghubi, Azad Shokri, Yousef Moghadas-Tabrizi, Abasali Keshtkar, Omid Sadeghi
COMPLEMENTARY THERAPIES IN MEDICINE
(2020)
Review
Biochemistry & Molecular Biology
Omid Asbaghi, Mehdi Sadeghian, Hassan Mozaffari-Khosravi, Vahid Maleki, Azad Shokri, Fatemeh Hajizadeh-Sharafabad, Mohammad Alizadeh, Omid Sadeghi
Review
Cardiac & Cardiovascular Systems
Omid Asbaghi, Mehdi Sadeghian, Faezeh Fouladvand, Bahman Panahande, Morteza Nasiri, Mahmoud Khodadost, Azad Shokri, Aliyar Pirouzi, Omid Sadeghi
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2020)
Review
Nutrition & Dietetics
Omid Asbaghi, Mehdi Sadeghian, Morteza Nasiri, Mahmoud Khodadost, Azad Shokri, Bahman Panahande, Aliyar Pirouzi, Omid Sadeghi
Review
Chemistry, Medicinal
Omid Asbaghi, Mehdi Sadeghian, Omid Sadeghi, Somaye Rigi, Shing Cheng Tan, Azad Shokri, Seyed Mohammad Mousavi
Summary: This study concluded that saffron supplementation did not have a significant impact on inflammatory biomarkers in adults. Further high-quality studies are needed to confirm the clinical efficacy of supplemental saffron on inflammation.
PHYTOTHERAPY RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Omid Sadeghi, Alireza Sadeghi, Hassan Mozaffari-Khosravi, Azad Shokri
Summary: The study evaluated the association between nutrient intake patterns and metabolic syndrome in Iranian adults. Adherence to a semi-plant nutrient pattern was initially linked to increased odds of MetS but became non-significant after adjusting for potential confounders. On the other hand, adherence to a semi-animal nutrient pattern was associated with a 26% higher likelihood of having MetS, even after adjusting for potential confounders.
PUBLIC HEALTH NUTRITION
(2021)
Article
Integrative & Complementary Medicine
Masoume Mansouri, Farshad Sharifi, Azad Shokri, Mehdi Varmaghani, Hamid Yaghubi, Yousef Moghadas-Tabrizi, Omid Sadeghi
Summary: The study revealed that frequent breakfast consumption is associated with decreased odds of primary headaches in female students and individuals with a BMI < 25 kg/m². Further prospective studies are required to confirm these findings.
COMPLEMENTARY THERAPIES IN MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Ebrahim Ghaderi, Hassan Mahmoodi, Pershang Sharifi Saqqezi, Reza Ghanei Gheshlagh, Ghobad Moradi, Azad Shokri, Bakhtiar Piroozi, Amjad Mohamadi Bolbanabad, Asad Ahmadi
Summary: A study conducted in Iran found that the level of knowledge about COVID-19 among residents is generally high, with most believing that the virus will eventually be successfully controlled globally, but lacking confidence in successful control within Iran. Gender, sources of information, and knowledge were identified as significantly associated with taking precautionary practices against COVID-19. Further research is recommended to improve knowledge levels, enhance positive attitudes, and improve behavioral patterns for successful control of COVID-19 in Iran.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Article
Multidisciplinary Sciences
Ghobad Moradi, Azad Shokri, Amjad Mohamadi-Bolbanabad, Bushra Zareie, Bakhtiar Piroozi
Summary: The study evaluated the quality of care for type 2 diabetic patients in Iran based on HbA1c levels. Results showed that more than 66% of diabetic patients had uncontrolled blood sugar levels, indicating a need for interventions to improve the quality of services provided to diabetic patients in Iran.
Review
Public, Environmental & Occupational Health
Ehsan Teymourzadeh, Mohamadkarim Bahadori, Hamed Fattahi, Hossein Ali Rahdar, Sima Mirzaei Moghadam, Azad Shokri
Summary: The study found that the prevalence of nosocomial infections in military hospitals is 8%, with the highest rates in burn units and ICUs. Risk factors for nosocomial infections included gender, age over 65, diabetes, inappropriate use of antibiotics, mechanical support, comorbidities, admission to the ICU, smoking, and BMI.
IRANIAN JOURNAL OF PUBLIC HEALTH
(2021)
Article
Health Policy & Services
Azad Shokri, Ghobad Moradi, Amjad Mohamadi Bolbanabad, Mitra Satary, Mahin Shabrandi, Parsa Sadeghkhani, Aram Mohammadi, Armin Ghorishi, Ronak Veisy, Arshad Veysi, Bakhtiar Piroozi, Shina Amiri Hoseini, Sonia Darvishi, Heshmatollah Asadi
Summary: The study investigated the perceived stigma among residents of Sanandaj following COVID-19 pandemic, with self-employers showing more concern about disclosing their illness and higher overall stigma scores. High levels of COVID-19 stigma were found among Iranians, particularly among men, youngsters, and self-employers.
INTERNATIONAL JOURNAL OF HUMAN RIGHTS IN HEALTH CARE
(2021)
Article
Psychiatry
Masoume Mansouri, Farshad Sharifi, Mehdi Varmaghani, Azad Shokri, HosseinAli Rahdar, Abasali Keshtkar, Omid Sadeghi
Summary: The study found that higher intake of fruits and vegetables is associated with reduced odds of primary headaches among university students. Specifically, increased fruit consumption was linked to a significant decrease in headache probability.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2021)
Article
Public, Environmental & Occupational Health
Rafat Mohebifar, Azad Shokri, Sima Rafiei, Negin Mohammadi, Maria Mohammadi, Sima Mirzaei Moghadam
IRANIAN JOURNAL OF PUBLIC HEALTH
(2020)
Article
Medicine, General & Internal
Mahboubeh Bayat, Azad Shokri, Elmira Mirbahaeddin, Roghaye Khalilnezhjad, Seyed Reza Khatibi, Hamed Fattahi, Gholamhossein Salehi Zalani, Faeze Ghasemi Seproo, Mahmoud Khodadost
ARCHIVES OF IRANIAN MEDICINE
(2020)