4.7 Article

Sleeping late is a risk factor for myopia development amongst school-aged children in China

Journal

SCIENTIFIC REPORTS
Volume 10, Issue 1, Pages -

Publisher

NATURE RESEARCH
DOI: 10.1038/s41598-020-74348-7

Keywords

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Funding

  1. Brien Holden Vision Institute, Discipline of Public Health - Eye health in Shanghai [15GWZK0601]
  2. Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai [2017YQ019]
  3. Three-year Action Program of Shanghai Municipality for Strengthening the Construction of the Public Health System (2011-2013) [2011-15]
  4. Three-year Action Program of Shanghai Municipality for Strengthening the Construction of the Public Health System (2015-2017) [GWIV-13.2]

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Myopia, a leading cause of distance vision impairment, is projected to affect half of the world's population in 30 years. We analysed the relationship between certain demographic, environmental, and behavioural factors and myopia from a 2-year school-based, prospective trial conducted in Shanghai, China. This trial enrolled 6295 school-aged children at baseline and followed them up for 24 months. The relationship between abovementioned factors and myopia was examined and the role of sleep in childhood myopia development was highlighted. Our results suggest that 'sleeping late' is a risk factor for myopia prevalence at baseline (odds ratio [OR]=1.55, p=0.04), 2-year myopia incidence (odds ratio [OR]=1.44, p=0.02) and progression over 24 months (p=0.005), after adjusting for residency area, age, gender, sleep duration, and time spent outdoors. The identification and consistency of results with late sleepers being a susceptible group to both myopia onset and progression suggests a complex relationship between circadian rhythm, indoor environment, habitual indoor activities and myopia development and progression. These results can offer new insights to future myopia aetiology studies as well as aid in decision-making of myopia prevention strategies.

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