STAT3 deficiency in B cells exacerbates uveitis by promoting expansion of pathogenic lymphocytes and suppressing regulatory B cells (Bregs) and Tregs

Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion

(2019) Deepali V. Sawant et al.   NATURE IMMUNOLOGY

A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance

(2019) Joëlle Khourieh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyper IgE Syndromes, Clinical & Molecular Characteristics

(2018) Taha Al-Shaikhly et al.   IMMUNOLOGY AND CELL BIOLOGY

Production of IL-35 by Bregs is mediated through binding of BATF-IRF-4-IRF-8 complex to il12a and ebi3 promoter elements

(2018) Cheng-Rong Yu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells

(2017) Anthony J. St. Leger et al.   IMMUNITY

IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease

(2017) Ivy M. Dambuza et al.   Nature Communications

IL-12p35 Inhibits Neuroinflammation and Ameliorates Autoimmune Encephalomyelitis

(2017) Jin Kyeong Choi et al.   Frontiers in Immunology

STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus

(2016) Chuanlin Ding et al.   JOURNAL OF IMMUNOLOGY

Interleukin 12 (IL-12) family cytokines: Role in immune pathogenesis and treatment of CNS autoimmune disease

(2015) Lin Sun et al.   CYTOKINE

Topical administration of a suppressor of cytokine signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis

(2015) Chang He et al.   JOURNAL OF AUTOIMMUNITY

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

Loss of STAT3 in CD4 + T Cells Prevents Development of Experimental Autoimmune Diseases

(2014) Xuebin Liu et al.   JOURNAL OF IMMUNOLOGY

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

STAT3 promotes survival of mutant photoreceptors in inherited photoreceptor degeneration models

(2014) Ke Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward a new STATe: The role of STATs in mitochondrial function

(2014) Jeremy A. Meier et al.   SEMINARS IN IMMUNOLOGY

Use of Optical Coherence Tomography and Electroretinography to Evaluate Retinal Pathology in a Mouse Model of Autoimmune Uveitis

(2013) Jun Chen et al.   PLoS One

STAT3 Protein Interacts with Class O Forkhead Transcription Factors in the Cytoplasm and Regulates Nuclear/Cytoplasmic Localization of FoxO1 and FoxO3a Proteins in CD4+T Cells

(2012) Hyun-Mee Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

STAT3 Protein Promotes T-cell Survival and Inhibits Interleukin-2 Production through Up-regulation of Class O Forkhead Transcription Factors

(2011) Hyun-Mee Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoreactive Memory CD4+ T Lymphocytes That Mediate Chronic Uveitis Reside in the Bone Marrow through STAT3-Dependent Mechanisms

(2011) H.-M. Oh et al.   JOURNAL OF IMMUNOLOGY

Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3

(2011) Karol Szczepanek et al.   MITOCHONDRION

Key role for IL-21 in experimental autoimmune uveitis

(2011) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CNTF and retina

(2011) Rong Wen et al.   PROGRESS IN RETINAL AND EYE RESEARCH

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

(2009) Charles E. Egwuagu   CYTOKINE

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

Roles of unphosphorylated STATs in signaling

(2008) Jinbo Yang et al.   CELL RESEARCH

A clinical grading system for retinal inflammation in the chronic model of experimental autoimmune uveoretinitis using digital fundus images

(2008) Heping Xu et al.   EXPERIMENTAL EYE RESEARCH

Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations

(2008) N. Wenta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA