Article
Chemistry, Inorganic & Nuclear
Selvakumari Ulagesan, Madhappan Santhamoorthy, Thi Phan Vy Phan, Krishnapandi Alagumalai, Kokila Thirupathi, Seong-Cheol Kim, Taek-Jeong Nam, Youn-Hee Choi
Summary: In this study, a mesoporous silica material containing amidoxime ligand groups was successfully synthesized through surface modification. The resulting SBA-15@AMI NPs exhibited a high concentration of amidoxime ligands on the surface, making them suitable for pH-responsive drug delivery applications in cancer therapy.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Malgorzata Zienkiewicz-Strzalka, Stanislaw Pikus, Malgorzata Skibinska, Magdalena Blachnio, Anna Derylo-Marczewska
Summary: This paper presents the synthesis and structural analysis of mesoporous silica materials using bentonite as an alternative silica source. The objective was to determine the effect of aluminum loading on the structure, porosity, and sorption capacity of thorium ions. The procedure involved gradually increasing the bentonite amount while reducing the TEOS content in the classic one-step synthesis of SBA-15 silicates. Characterization techniques such as XRD, SAXS, TEM, SEM, nitrogen adsorption-desorption, and potentiometric titration were used. The study proposes cost-effective composites for Th(IV) ion removal by expanding the porous surface using bentonite as a silica precursor and incorporating thorium-binding groups.
Article
Pharmacology & Pharmacy
Klara Szentmihalyi, Szilvia Klebert, Zoltan May, Eszter Bodis, Miklos Mohai, Laszlo Trif, Tivadar Feczko, Zoltan Karoly
Summary: By immobilizing MTZ molecules on mesoporous silica carriers, this study achieved higher fixation rates and faster dissolution rates, providing a new approach to reduce drug dosage while maintaining high efficiency.
Article
Chemistry, Applied
Christopher M. A. Parlett, Hamidreza Arandiyan, Lee J. Durndell, Mark A. Isaacs, Antonio Torres Lopez, Roong J. Wong, Karen Wilson, Adam F. Lee
Summary: The article demonstrates a method for continuous flow synthesis of SBA-15 at high yield at 80 degrees C using a simple tube reactor. The resulting SBA-15 exhibits excellent textural properties and far higher productivity than previously reported in batch or flow synthesis.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Engineering, Environmental
Fernanda Rechotnek, Heveline D. M. Follmann, Rafael Silva
Summary: The use of chemically decorated mesoporous silica with L-cysteine has shown promising results in electrochemical sensing of heavy metals, with pore size appearing to be the most relevant factor for efficiency. SBA-15/L-cys with larger pores outperformed MCM-41/L-cys in terms of detection limit for cadmium and lead ions.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Environmental Sciences
Zeinab Ezzeddine, Isabelle Batonneau-Gener, Yannick Pouilloux
Summary: The removal of zinc ions from water was studied using two types of ordered mesoporous silica (SBA-15 and SBA-16). Both materials were modified with APTES and EDTA through post grafting methods. The modified adsorbents were characterized by various analytical techniques, and the structural integrity was maintained. Optimal adsorption conditions and maximum adsorption capacity were determined through experimental tests, and the regenerated adsorbent showed no significant decline in adsorption efficiency.
Article
Physics, Applied
Fnu Gorky, Shelby R. Guthrie, Courtney S. Smoljan, James M. Crawford, Moises A. Carreon, Maria L. Carreon
Summary: The mesoporous SBA-15 silica material demonstrated significantly higher efficiency in synthesizing ammonia through atmospheric dielectric barrier discharge plasma, mainly due to its hierarchically ordered pore structure that facilitates the diffusion of plasma discharge into the pores.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Chemistry, Physical
Hongxia Liu, Yijia Lao, Jiayi Wang, Junjie Jiang, Chuanbai Yu, Yuanli Liu
Summary: The development of composite materials with functional additives proved to be an effective way to improve or supplement the required properties of polymers. In this study, mesoporous silica (SBA-15) with different pore sizes were used as functional additives to prepare SBA-15/PF (phenolic resin) nanocomposites. The results revealed that the pore sizes of SBA-15 have a significant effect on the resulting SBA-15/PF hybrid and SBA-15/PF nanocomposites, with enhanced thermal and frictional properties.
Article
Chemistry, Multidisciplinary
Dimitrios Gkiliopoulos, Ioannis Tsamesidis, Anna Theocharidou, Georgia K. Pouroutzidou, Evi Christodoulou, Evangelia Stalika, Konstantinos Xanthopoulos, Dimitrios Bikiaris, Konstantinos Triantafyllidis, Eleana Kontonasaki
Summary: The study successfully synthesized SBA-15 mesoporous silica materials with varying porosity and evaluated their biocompatibility with hPDLCs, as well as their effectiveness as carriers of rh-BMP-2. Results indicated that SBA-15 MSNs may play a significant role in the effective release of bone-inducing proteins.
Review
Chemistry, Multidisciplinary
Chun Xu, Chang Lei, Yue Wang, Chengzhong Yu
Summary: Dendritic mesoporous silica nanoparticles have attracted attention due to their wide applications, but the terminology used is ambiguous. This review provides a critical analysis of reported dendritic silica nanoparticles according to their structural classification, updating the understanding of their formation mechanisms and the control of structural parameters. The review also focuses on the applications of dendritic mesoporous nanoparticles in the biomedical field, offering new insights into the structure-property relationship.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Materials Science, Multidisciplinary
Leticia F. Rasteiro, Abdul Motin, Luiz H. Vieira, Elisabete M. Assaf, Francisco Zaera
Summary: The atomic layer deposition of ZrO2 thin films over mesopores of SBA-15 was studied using TDMAZ as ZrO2 precursor. The thickness of the films was controlled by the number of deposition cycles. The homogeneous distribution of ZrO2 throughout the SBA-15 pores was confirmed by various characterization techniques. The deposition rate was observed to slow down after 4 cycles, possibly due to mass transport limitations caused by the chemisorption properties of TDMAZ and the pore diameter of SBA-15.
Article
Materials Science, Multidisciplinary
Z. A. A. Halim, M. A. Mat Yajid, N. Ahmad
Summary: The thermal degradation of mesoporous hydrated silica (MHS), mesoporous silica (MS), and alumina trihydrate (ATH) hybrid systems for flame retardant materials was investigated. The results show that MHS-ATH has higher thermal stability and a wider range of water release temperature, improving the flame retardancy effect compared to ATH.
Article
Chemistry, Applied
Joanna Dobrzynska, Rafal Olchowski, Emil Zieba, Ryszard Dobrowolski
Summary: A hybrid Zr/amine-modified mesoporous silica sorbent was proposed for preconcentration of inorganic As from drinking water before FI HG AAS determination. Different sorbents were synthesized and characterized, with SBA/TMPED/Zr-0.5 chosen for its effective adsorption capacity. The method showed good linearity, low detection limits, and high recovery rates for arsenic from water samples.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Engineering, Environmental
Qiang Zhang, Xue-Yan Wu, Kai-Xue Wang, Jie-Sheng Chen
Summary: This study improves the performance of lithium metal batteries by adding mesoporous silica to the electrolyte, inhibiting the uncontrolled growth of lithium dendrites and electrolyte consumption.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Gabriela Marinescu, Daniela C. Culita, Teodora Mocanu, Raul-Augustin Mitran, Simona Petrescu, Miruna S. Stan, Mariana C. Chifiriuc, Marcela Popa
Summary: A series of nanostructured materials were obtained by functionalizing SBA-15 mesoporous silica with Ru(II) and Ru(III) complexes bearing Schiff base ligands. The resulting materials showed antitumoral activity against lung tumor cells and inhibitory effects against bacteria.
Article
Biochemistry & Molecular Biology
Izabela Nowak, Akmaral Issayeva, Marta Dabrowska, Agata Wawrzynczak, Henryk Jelen, Boguslawa Leska, Azhar Abubakirova, Assel Tleukeyeva
Summary: This study aimed to explore the potential of combining medicinal plants with salt-containing raw materials from the Aral Sea region for cosmetic purposes. The chemical and mineralogical compositions of salts in this region were analyzed for their pharmacological and cosmetic applications. The salt-containing raw materials were characterized using various techniques, and the microflora of these materials and flora of the Zhaksy-Klych lake were studied. The volatile compound composition of selected plant species for future cosmetic products was determined. Tests on cosmetic compositions developed from plant extracts and salt-containing raw materials demonstrated moisturizing effects in three samples. The production of cosmetic products in the Aral region would not only alleviate social tensions but also improve the environmental situation.
Article
Biochemistry & Molecular Biology
Aleksandra Zielinska, Krzysztof Wojcicki, Dorota Klensporf-Pawlik, Marta Marzec, Massimo Lucarini, Alessandra Durazzo, Joel Fonseca, Antonello Santini, Izabela Nowak, Eliana B. Souto
Summary: Pomegranate seed oil is a rich source of conjugated linolenic acid with nutritional and therapeutic properties. The main component in pomegranate seed oil is 9,11,13-octadic-trienoic acid (18:3), accounting for 73% of the total fatty acids.
Article
Chemistry, Physical
Ewelina Musielak, Agnieszka Feliczak-Guzik, Mietek Jaroniec, Izabela Nowak
Summary: Hierarchical zeolites are used as pharmaceutical carrier systems to encapsulate low water-soluble active substances and improve bioavailability and adsorption properties.
Article
Materials Science, Biomaterials
Agnieszka Feliczak-Guzik, Ewelina Musielak, Izabela Nowak
Summary: This paper describes the synthesis of hierarchical zeolites by modifying a commercial FAU zeolite with chitosan. The addition of silicon source and the type of structuring agent used were varied during synthesis. The synthesised materials were characterised using various techniques, confirming the presence of additional porosity. Adsorption experiments showed that the hierarchical zeolite-modified chitosan had a high adsorption capacity of 1.2 cm3 g-1.
PROGRESS ON CHEMISTRY AND APPLICATION OF CHITIN AND ITS DERIVATIVES
(2022)
Article
Biochemistry & Molecular Biology
Sylwia Chalupniczak, Izabela Nowak, Agata Wawrzynczak
Summary: In this study, KIT-5 materials were effectively functionalized with sulfonic groups using grafting or the co-condensation method and tested as solid acid catalysts. The co-condensation method successfully produced stable -SO3H functionalized KIT-5 materials. The influence of synthesis methods on various parameters and the catalytic activity of -SO3H/KIT-5 materials was thoroughly investigated. Different functionalization techniques and modifying agent amounts were evaluated for their impact on the ordering of the mesoporous structure of KIT-5 materials. The synthesized materials showed promise as acid catalysts in heterogeneous catalysis reactions, particularly in Friedel-Crafts alkylation processes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Jagoda Chudzinska, Bartosz Wozniak, Myroslav Sprynskyy, Izabela Nowak, Agnieszka Feliczak-Guzik
Summary: This study aimed to design an effective method for the photocatalytic removal of bisphenol A using hierarchical zeolites and ruthenium ion-modified diatom biosilica loaded with silver as photocatalysts. The reaction conditions including temperature, pH, composition of the reaction mixture, and electromagnetic wavelength were optimized. The ruthenium ion-modified biosilica showed the highest efficiency for bisphenol A removal at a rate higher than 99%.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Agata Wawrzynczak, Izabela Nowak, Natalia Wozniak, Jagoda Chudzinska, Agnieszka Feliczak-Guzik
Summary: This study focuses on the synthesis and characterization of hierarchical zeolites with secondary mesoporosity, using commercial zeolites and modified with polysaccharides. The materials were characterized and tested as carriers for bioactive molecules. Preliminary studies have shown the potential of hierarchical zeolites as carriers for different therapeutic molecules.
Editorial Material
Biochemistry & Molecular Biology
Izabela Nowak, Agnieszka Feliczak-Guzik
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nanoscience & Nanotechnology
Tomasz Kostrzewa, Izabela Nowak, Agnieszka Feliczak-Guzik, Joanna Drzezdzon, Dagmara Jacewicz, Magdalena Gorska-Ponikowska, Alicja Kuban-Jankowska
Summary: Solid lipid nanoparticles (SLN) have shown promising potential as a drug delivery system for the treatment of various human diseases, including cancers. Encapsulation of two compounds into SLNs increased their cytotoxicity against MDA-MB-231 breast cancer cell line and enhanced the effect of vincristine.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Chemistry, Physical
Ewelina Musielak, Agnieszka Feliczak-Guzik, Mietek Jaroniec, Izabela Nowak
Summary: Photodynamic therapy (PDT) is a promising alternative to traditional active substance release methods, utilizing photosensitizers and specific energy radiation. Curcumin, a natural photosensitizer, has anti-inflammatory, antioxidant, and anti-cancer effects. However, the solubility of curcumin in water limits its clinical application in PDT. Using hierarchical zeolites as carriers is a potential strategy to overcome this difficulty.
Article
Biochemistry & Molecular Biology
Katarzyna Pikosz, Izabela Nowak, Agnieszka Feliczak-Guzik
Summary: The study aimed to develop a topical formulation for arthritis relief. A combination of icariin from Epimedium L. extract and glucosamine sulfate was tested. Permeation studies confirmed their potential for skin permeation, although in vitro release did not accurately reflect skin permeation. The release of icariin was higher for the plant extract (15.0-19.0%) and pure substance (29.0-35.0%) compared to oral administration (12.0%), indicating the potential superiority of topical application. Physicochemical parameters affecting release and performance were addressed. This preliminary research and permeation analysis show promising prospects, but further investigation is needed.
Article
Biochemistry & Molecular Biology
Bartosz Wozniak, Jagoda Chudzinska, Paulina Szczyglewska, Izabela Nowak, Agnieszka Feliczak-Guzik
Summary: Based on recent trends, there is an increasing interest in cosmetic products made from natural raw materials that are considered safe for human use. These materials include plant extracts containing proteins, vitamins, minerals, phospholipids, antioxidants, and natural preservatives. One example is Tremella fuciformis extract, which acts as a natural alternative to hyaluronic acid. This extract retains water in the skin cells, stimulates the skin to combat free radicals, and prevents premature skin aging. The study aimed to optimize the composition of natural cosmetic formulations and characterize their physicochemical and skin care properties. Formulations containing Tremella fuciformis extract reduced transepidermal water loss (TEWL) by 12.4% compared to formulations without this active ingredient, and effectively hydrated the epidermis as confirmed by instrumental methods. Dermatological tests showed no erythema, swelling, or irritation in volunteers 48 and 72 hours after product application.
Review
Biochemistry & Molecular Biology
Paulina Szczyglewska, Agnieszka Feliczak-Guzik, Izabela Nowak
Summary: The role of nanotechnology is becoming increasingly important in society, as scientists are able to manipulate materials at the atomic and molecular scale. Nanomaterials, especially metallic nanoparticles, have unique properties and are indispensable in various fields. This article introduces the basic aspects of nanotechnology, discusses methods for synthesizing nanoparticles, and describes their types, properties, and applications.
Article
Chemistry, Physical
Paulina Szczyglewska, Agnieszka Feliczak-Guzik, Sylwia Chalupniczak, Izabela Nowak
Summary: This study aims to synthesize, characterize, and apply new hierarchical materials modified with tantalum and vanadium ions. These materials have secondary porosity, allowing reactant molecules to access active sites while maintaining acidity and crystallinity. The results show that these systems exhibit high activity and selectivity in the oxidation of cyclohexene. Comparison of conventional and microwave-assisted oxidation processes reveals that the hierarchical FAU zeolite with Ta can shorten reaction times and improve activity and selectivity under the same experimental conditions.
Article
Biology
Agnieszka Nowak-Terpilowska, Izabela Nowak, Agnieszka Feliczak-Guzik, Marzena Wyganowska
Summary: The ethanol extracts of Calendula officinalis L. have no inhibitory effect on gingival fibroblasts and can reduce the cytotoxic influence of alcohol on these cells.
