Multifunctional Islet Transplantation Hydrogel Encapsulating A20 High-Expressing Islets

Using Recombinant Human Collagen With Basic Fibroblast Growth Factor to Provide a Simulated Extracellular Matrix Microenvironment for the Revascularization and Attachment of Islets to the Transplantation Region

(2020) Qunyan Zhu et al.   Frontiers in Pharmacology

Studies on the Mechanisms of Anti-Inflammatory Activity of Heparin- and Hyaluronan-Containing Multilayer Coatings—Targeting NF-κB Signalling Pathway

(2020) Hala Alkhoury et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adipose tissue-derived mesenchymal stem cells rescue the function of islets transplanted in sub-therapeutic numbers via their angiogenic properties

(2019) Gang Ren et al.   CELL AND TISSUE RESEARCH

Co-transplantation of pre-activated mesenchymal stem cells improves intraportal engraftment of islets by inhibiting liver natural killer cells in mice

(2019) Nobuki Ishida et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Nanotechnology in cell replacement therapies for type 1 diabetes

(2019) Alexander U. Ernst et al.   ADVANCED DRUG DELIVERY REVIEWS

Interconnected Toroidal Hydrogels for Islet Encapsulation

(2019) Alexander U. Ernst et al.   Advanced Healthcare Materials

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

(2019) Dario Priem et al.   Cell Death & Disease

Advances in β-cell replacement therapy for the treatment of type 1 diabetes

(2019) Marie-Christine Vantyghem et al.   LANCET

Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus

(2019) Albert Espona-Noguera et al.   Pharmaceutics

Design of a vascularized synthetic poly(ethylene glycol) macroencapsulation device for islet transplantation

(2018) Jessica D. Weaver et al.   BIOMATERIALS

Bioengineering with Endothelial Progenitor Cells Improves the Vascular Engraftment of Transplanted Human Islets

(2018) Liza Grapensparr et al.   CELL TRANSPLANTATION

MSCs promote the development and improve the function of neonatal porcine islet grafts

(2018) Sirong He et al.   FASEB JOURNAL

Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice

(2018) Yaqi Yin et al.   Cell Death & Disease

A Model for Human Islet Transplantation to Immunodeficient Streptozotocin-Induced Diabetic Mice

(2018) Elisabet Estil·les et al.   CELL TRANSPLANTATION

Layered PEGDA hydrogel for islet of Langerhans encapsulation and improvement of vascularization

(2017) Giulia Marchioli et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Pancreatic islet surface bioengineering with a heparin-incorporated starPEG nanofilm

(2017) Shaofeng Lou et al.   Materials Science & Engineering C-Materials for Biological Applications

Development of hydrogels for regenerative engineering

(2017) Xiaofei Guan et al.   Biotechnology Journal

IGF-2 coated porous collagen microwells for the culture of pancreatic islets

(2017) A. Forget et al.   Journal of Materials Chemistry B

Human Amniotic Membrane Mesenchymal Stem Cells inhibit Neutrophil Extracellular Traps through TSG-6

(2017) Fátima Sofía Magaña-Guerrero et al.   Scientific Reports

Combination strategy of multi-layered surface camouflage using hyperbranched polyethylene glycol and immunosuppressive drugs for the prevention of immune reactions against transplanted porcine islets

(2016) Muhammad R. Haque et al.   BIOMATERIALS

Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes

(2016) João Paulo M. C. M. Cunha et al.   DIABETOLOGIA

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

Evolution of Islet Transplantation for the Last 30 Years

(2016) Alan C. Farney et al.   PANCREAS

Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism

(2016) Anoop Babu Vasandan et al.   Scientific Reports

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

(2015) Ingrid E. Wertz et al.   NATURE

Islet cell transplant and the incorporation of Tregs

(2014) Adam Krzystyniak et al.   Current Opinion in Organ Transplantation

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Advances and Contributions

(2014) D. M. Nathan et al.   DIABETES

Mesenchymal stem cells and ligand incorporation in biomimetic poly(ethylene glycol) hydrogels significantly improve insulin secretion from pancreatic islets

(2014) Tuğba Bal et al.   Journal of Tissue Engineering and Regenerative Medicine

Microencapsulation of cells, including islets, within stable ultra-thin membranes of maleimide-conjugated PEG-lipid with multifunctional crosslinkers

(2013) Yuji Teramura et al.   BIOMATERIALS

Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes

(2013) Edward A. Phelps et al.   BIOMATERIALS

Alloantibody and Autoantibody Monitoring Predicts Islet Transplantation Outcome in Human Type 1 Diabetes

(2012) L. Piemonti et al.   DIABETES

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

(2010) Y. Chu et al.   BLOOD

Integrin α3, But Not β1, Regulates Islet Cell Survival and Function via PI3K/Akt Signaling Pathways

(2010) Mansa Krishnamurthy et al.   ENDOCRINOLOGY

Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells

(2009) A. M. Madec et al.   DIABETOLOGIA