Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease

Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

(2014) Alban Ordureau et al.   MOLECULAR CELL

Mass-spectrometry-based draft of the human proteome

(2014) Mathias Wilhelm et al.   NATURE

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

Translational control of immune responses: from transcripts to translatomes

(2014) Ciriaco A Piccirillo et al.   NATURE IMMUNOLOGY

Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms

(2014) Brigit E. Riley et al.   PLoS One

Impact of regulatory variation from RNA to protein

(2014) A. Battle et al.   SCIENCE

Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson's Leukocytes Identified by RNA Sequencing

(2014) Lilach Soreq et al.   PLoS Computational Biology

Environmental Toxins and Parkinson's Disease

(2013) Samuel M. Goldman   Annual Review of Pharmacology and Toxicology

Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies

(2013) Stefan Schildknecht et al.   JOURNAL OF NEUROCHEMISTRY

α-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease

(2013) Stephen Mullin et al.   MOLECULAR NEUROBIOLOGY

Variation and genetic control of protein abundance in humans

(2013) Linfeng Wu et al.   NATURE

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Proteomics: from single molecules to biological pathways

(2012) Sarah R. Langley et al.   CARDIOVASCULAR RESEARCH

The Central Theme of Parkinson’s Disease: α-Synuclein

(2012) Mehmet Ozansoy et al.   MOLECULAR NEUROBIOLOGY

Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease

(2012) Edward C. Lauterbach   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation

(2012) Alexandra Dumitriu et al.   PLoS Genetics

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2

(2011) Nathan Pankratz et al.   ANNALS OF NEUROLOGY

Neuroprotective and neuroregenerative properties of metallothioneins

(2011) Cecília R. A. Santos et al.   IUBMB LIFE

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

(2011) Lily Ting et al.   NATURE METHODS

Up-regulation of metallothionein gene expression in Parkinsonian astrocytes

(2011) Gregory J. Michael et al.   NEUROGENETICS

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Control of NF-κB activation by the COP9 signalosome

(2010) Katrin Schweitzer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease

(2010) Amélie C. Lanoue et al.   EXPERIMENTAL NEUROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Analysis of proteome dynamics in the mouse brain

(2010) J. C. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Parkinson's disease: from monogenic forms to genetic susceptibility factors

(2009) S. Lesage et al.   HUMAN MOLECULAR GENETICS

The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry

(2008) Judit Villén et al.   Nature Protocols

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics