The power of fission: yeast as a tool for understanding complex splicing

A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human

(2016) Tommy V. Vo et al.   CELL

CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast

(2016) Thi Hoang Duong Nguyen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

How Are Short Exons Flanked by Long Introns Defined and Committed to Splicing?

(2016) Dror Hollander et al.   TRENDS IN GENETICS

Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast

(2016) Amy Larson et al.   G3-Genes Genomes Genetics

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast

(2015) Danny A. Bitton et al.   GENOME RESEARCH

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

(2015) Thi Hoang Duong Nguyen et al.   NATURE

SR protein kinases promote splicing of nonconsensus introns

(2015) Jesse J Lipp et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Widespread alternative and aberrant splicing revealed by lariat sequencing

(2015) Nicholas Stepankiw et al.   NUCLEIC ACIDS RESEARCH

Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast

(2015) Noriko Sasaki-Haraguchi et al.   PLoS One

Structure of a yeast spliceosome at 3.6-angstrom resolution

(2015) Chuangye Yan et al.   SCIENCE

SR protein kinases promote splicing of nonconsensus introns

(2015) Jesse J Lipp et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast

(2015) Kristin L. Patrick et al.   PLoS Genetics

Microexons--Tiny but mighty

(2014) C. Scheckel et al.   EMBO JOURNAL

Deep mutational scanning: a new style of protein science

(2014) Douglas M Fowler et al.   NATURE METHODS

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome

(2014) Changwei Shao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Widespread Use of Non-productive Alternative Splice Sites in Saccharomyces cerevisiae

(2014) Tadashi Kawashima et al.   PLoS Genetics

Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe

(2013) Jun Gao et al.   CURRENT GENETICS

Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing

(2013) Shatakshi Pandit et al.   MOLECULAR CELL

Lariat sequencing in a unicellular yeast identifies regulated alternative splicing of exons that are evolutionarily conserved with humans

(2013) A. R. Awan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Splicing and Subfunctionalization Generates Functional Diversity in Fungal Proteomes

(2013) Alexandra N. Marshall et al.   PLoS Genetics

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution

(2012) Robert K. Bradley et al.   PLOS BIOLOGY

Exon and intron definition in pre-mRNA splicing

(2012) Laura De Conti et al.   Wiley Interdisciplinary Reviews-RNA

Deep mutational scanning: assessing protein function on a massive scale

(2011) Carlos L. Araya et al.   TRENDS IN BIOTECHNOLOGY

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Alternative Splicing of PTC7 in Saccharomyces cerevisiae Determines Protein Localization

(2009) K. Juneau et al.   GENETICS

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution

(2008) Brian T. Wilhelm et al.   NATURE

Human branch point consensus sequence is yUnAy

(2008) Kaiping Gao et al.   NUCLEIC ACIDS RESEARCH