Journal
NATURE COMMUNICATIONS
Volume 11, Issue 1, Pages -Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41467-020-18849-z
Keywords
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Funding
- European Health Data and Evidence Network (EHDEN) project
- Innovative Medicines Initiative 2 Joint Undertaking (JU) [806968]
- European Union
- EFPIA
- National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC)
- US National Institutes of Health
- US Department of Veterans Affairs
- Janssen Research Development
- IQVIA
- Bio Industrial Strategic Technology Development Program - Ministry of Trade, Industry & Energy (MOTIE, Korea) [20001234]
- Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI)
- Ministry of Health & Welfare, Republic of Korea [HI16C0992]
- Versus Arthritis [21605]
- Medical Research Council Doctoral Training Partnership (MRC-DTP) [MR/K501256/1]
- Medical Research Council (MRC)
- Fundacion Alfonso Martin Escudero (FAME)
- Innovation Fund Denmark [5153-00002B]
- Novo Nordisk Foundation [NNF14CC0001]
- VINCI [VA HSR RES 13-457]
- NIHR Senior Research Fellowship [SRF-2018-11-ST2-004]
- Bill & Melinda Gates Foundation [INV-016201]
- Intramural Research Program of the National Institutes of Health/National Library of Medicine/Lister Hill National Center for Biomedical Communications
- Direccio General de Recerca i Innovacio en Salut from the Department of Health of the Generalitat de Catalunya
- Health Data Compass Data Warehouse project
- Intramural Research Program, National Institute of Health
- MRC [2122671] Funding Source: UKRI
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Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19. Detailed knowledge of the characteristics of COVID-19 patients helps with public health planning. Here, the authors use routinely-collected data from seven databases in three countries to describe the characteristics of >30,000 patients admitted with COVID-19 and compare them with those admitted for influenza in previous years.
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