IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
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Title
IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-09-14
DOI
10.1038/s41467-020-18244-8
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Note: Only part of the references are listed.- MyD88 signalling is critical in the development of pancreatic cancer cachexia
- (2019) Xinxia Zhu et al. Journal of Cachexia Sarcopenia and Muscle
- Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
- (2019) Luca Cassetta et al. CANCER CELL
- Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma
- (2019) Eileen M. O’Reilly et al. JAMA Oncology
- Inflammatory cytokines and combined biomarker panels in pancreatic ductal adenocarcinoma: Enhancing diagnostic accuracy
- (2019) Deirdré Kruger et al. PLoS One
- NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma
- (2017) Donnele Daley et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance
- (2017) Kristen B. Long et al. MOLECULAR IMMUNOLOGY
- The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors
- (2017) Louisa Bolm et al. Translational Oncology
- Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways
- (2017) Guohua Zhang et al. Scientific Reports
- IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer
- (2016) Thomas A Mace et al. GUT
- Phase 1/2a study of double immune suppression blockade by combining a CSF1R inhibitor (pexidartinib/PLX3397) with an anti PD-1 antibody (pembrolizumab) to treat advanced melanoma and other solid tumors.
- (2016) Zev A. Wainberg et al. JOURNAL OF CLINICAL ONCOLOGY
- nab-paclitaxel (nab-P) + nivolumab (Nivo) ± gemcitabine (Gem) in patients (pts) with advanced pancreatic cancer (PC).
- (2016) Irfan Firdaus et al. JOURNAL OF CLINICAL ONCOLOGY
- Mechanisms of PD-L1/PD-1-mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the E -TCL1 CLL mouse model
- (2015) F. McClanahan et al. BLOOD
- Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6Clow F4/80+ Extratumoral Macrophages
- (2015) Gregory L. Beatty et al. GASTROENTEROLOGY
- Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells
- (2015) Abdullah Alsuliman et al. Molecular Cancer
- Anti-IL-20 Monoclonal Antibody Suppresses Prostate Cancer Growth and Bone Osteolysis in Murine Models
- (2015) Yu-Hsiang Hsu et al. PLoS One
- Functional significance of macrophages in pancreatic cancer biology
- (2015) Hai Hu et al. TUMOR BIOLOGY
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia
- (2014) Michele Petruzzelli et al. Cell Metabolism
- IL-20 and IL-20R1 antibodies protect against liver fibrosis
- (2014) Yi-Shu Chiu et al. HEPATOLOGY
- Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
- (2014) Serkan Kir et al. NATURE
- Role of α5β1 Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells
- (2014) Hongren Yao et al. Translational Oncology
- Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
- (2013) Wei Ying et al. Jove-Journal of Visualized Experiments
- Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice
- (2012) M. Tsoli et al. CANCER RESEARCH
- Anti-IL-20 Monoclonal Antibody Suppresses Breast Cancer Progression and Bone Osteolysis in Murine Models
- (2012) Y.-H. Hsu et al. JOURNAL OF IMMUNOLOGY
- Anti-IL-20 Monoclonal Antibody Alleviates Inflammation in Oral Cancer and Suppresses Tumor Growth
- (2012) Y.-H. Hsu et al. MOLECULAR CANCER RESEARCH
- Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence
- (2011) Carmen Guerra et al. CANCER CELL
- Relative Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Tumor Necrosis Factor-α (TNF-α)-induced Lipolysis in Adipocytes
- (2011) Xingyuan Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti–IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss
- (2011) Yu-Hsiang Hsu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia
- (2011) S. K. Das et al. SCIENCE
- Pancreatic cancerrelated cachexia: influence on metabolism and correlation to weight loss and pulmonary function
- (2009) Jeannine Bachmann et al. BMC CANCER
- IL-20 Is Regulated by Hypoxia-Inducible Factor and Up-Regulated after Experimental Ischemic Stroke
- (2009) W.-Y. Chen et al. JOURNAL OF IMMUNOLOGY
- Mechanisms of Cancer Cachexia
- (2009) Michael J. Tisdale PHYSIOLOGICAL REVIEWS
- Interleukin-20 induced cell death in renal epithelial cells and was associated with acute renal failure
- (2008) H-H Li et al. GENES AND IMMUNITY
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