Inferring drug-disease associations based on known protein complexes

Levomilnacipran: a newly approved drug for treatment of major depressive disorder

(2014) Rajnish Mago et al.   Expert Review of Clinical Pharmacology

Network-Based Drug Ranking and Repositioning with Respect to DrugBank Therapeutic Categories

(2013) Matteo Re et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Desvenlafaxine-Induced Worsening of Hypertension

(2013) Ravindra Neelakanthappa Munoli et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Prediction of human genes and diseases targeted by xenobiotics using predictive toxicogenomic-derived models (PTDMs)

(2013) Feixiong Cheng et al.   Molecular BioSystems

Network-based drug repositioning

(2013) Zikai Wu et al.   Molecular BioSystems

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

A CTD-Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug-disease and drug-phenotype interactions

(2013) A. P. Davis et al.   Database-The Journal of Biological Databases and Curation

A co-module approach for elucidating drug–disease associations and revealing their molecular basis

(2012) Shiwen Zhao et al.   BIOINFORMATICS

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

(2012) Hee Lee et al.   BMC Systems Biology

A pathway profile-based method for drug repositioning

(2012) Hao Ye et al.   CHINESE SCIENCE BULLETIN

Rotigotine transdermal patch for the treatment of Parkinson’s Disease

(2012) Santiago Perez-Lloret et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Drug repositioning through incomplete bi-cliques in an integrated drug–target–disease network

(2012) Simone Daminelli et al.   Integrative Biology

Detecting overlapping protein complexes in protein-protein interaction networks

(2012) Tamás Nepusz et al.   NATURE METHODS

A Randomized, Double-Blind, Placebo-Controlled, 8-Week Study of Vilazodone, a Serotonergic Agent for the Treatment of Major Depressive Disorder

(2011) Arif Khan et al.   JOURNAL OF CLINICAL PSYCHIATRY

Detecting and analyzing differentially activated pathways in brain regions of Alzheimer's disease patients

(2011) Zhi-Ping Liu et al.   Molecular BioSystems

SNP-based analysis of neuroactive ligand–receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: Data from the CATIE study

(2011) Daniel E. Adkins et al.   SCHIZOPHRENIA RESEARCH

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

PROMISCUOUS: a database for network-based drug-repositioning

(2010) J. von Eichborn et al.   NUCLEIC ACIDS RESEARCH

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations

(2009) P. Du et al.   BIOINFORMATICS

Annotating the human genome with Disease Ontology

(2009) John D Osborne et al.   BMC GENOMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

Revealing Targeted Therapy for Human Cancer by Gene Module Maps

(2008) D. J. Wong et al.   CANCER RESEARCH

Serotonin Receptors

(2008) David E. Nichols et al.   CHEMICAL REVIEWS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Cognition enhancers between treating and doping the mind

(2008) Cristina Lanni et al.   PHARMACOLOGICAL RESEARCH