Immune signature driven by ADT-induced immune microenvironment remodeling in prostate cancer is correlated with recurrence-free survival and immune infiltration

Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging concepts

(2020) Jean-David Fumet et al.   EUROPEAN JOURNAL OF CANCER

FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes

(2019) Elizabeth J. Adams et al.   NATURE

Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly

(2019) Qing Shi et al.   Molecular Cancer

Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression

(2018) Shancheng Ren et al.   EUROPEAN UROLOGY

Spatial Intratumor Genomic Heterogeneity within Localized Prostate Cancer Revealed by Single-nucleus Sequencing

(2018) Fei Su et al.   EUROPEAN UROLOGY

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Transcriptomic features of primary prostate cancer and their prognostic relevance to castration-resistant prostate cancer

(2017) Seok Joong Yun et al.   Oncotarget

Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy

(2017) Shuang G. Zhao et al.   JAMA Oncology

Sequencing of Sipuleucel-T and Androgen Deprivation Therapy in Men with Hormone-Sensitive Biochemically Recurrent Prostate Cancer: A Phase II Randomized Trial

(2016) Emmanuel S. Antonarakis et al.   CLINICAL CANCER RESEARCH

SOCS3 Modulates the Response to Enzalutamide and Is Regulated by Androgen Receptor Signaling and CpG Methylation in Prostate Cancer Cells

(2016) F. Handle et al.   MOLECULAR CANCER RESEARCH

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

(2015) Mihaela Angelova et al.   GENOME BIOLOGY

Androgen deprivation therapy sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway

(2015) Andressa Ardiani et al.   Oncotarget

PD-L1 is highly expressed in Enzalutamide resistant prostate cancer

(2015) Jennifer L. Bishop et al.   Oncotarget

Loss of JUNB/AP-1 promotes invasive prostate cancer

(2014) M K Thomsen et al.   CELL DEATH AND DIFFERENTIATION

Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a cancer vaccine

(2014) Anna R Kwilas et al.   Journal of Translational Medicine

Combination Therapy with a Second-Generation Androgen Receptor Antagonist and a Metastasis Vaccine Improves Survival in a Spontaneous Prostate Cancer Model

(2013) A. Ardiani et al.   CLINICAL CANCER RESEARCH

Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy

(2013) Prabhakar Rajan et al.   EUROPEAN UROLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

(2013) Nadia J Kershaw et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

The Tipping Point for Combination Therapy: Cancer Vaccines With Radiation, Chemotherapy, or Targeted Small Molecule Inhibitors

(2012) James W. Hodge et al.   SEMINARS IN ONCOLOGY

Phase I trial of tremelimumab in combination with short-term androgen deprivation in patients with PSA-recurrent prostate cancer

(2011) Douglas G. McNeel et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Overall Survival Analysis of a Phase II Randomized Controlled Trial of a Poxviral-Based PSA-Targeted Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

Flexible hazard ratio curves for continuous predictors in multi-state models

(2010) Carmen Cadarso-Suárez et al.   STATISTICAL MODELLING

Induction of neuronal apoptosis inhibitory protein expression in response to androgen deprivation in prostate cancer

(2009) Helen H.L. Chiu et al.   CANCER LETTERS

RNA-destabilizing Factor Tristetraprolin Negatively Regulates NF-κB Signaling

(2009) Jian Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY