The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay

CNP deficiency causes severe hypomyelinating leukodystrophy in humans

(2020) Lama Al-Abdi et al.   HUMAN GENETICS

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model

(2020) Sophie B Siems et al.   eLife

Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS

(2020) Daniel C. Factor et al.   CELL

Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

(2020) Yannick Poitelon et al.   Cells

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

(2019) Michelle S Erwig et al.   eLife

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Diagnosis, prognosis, and treatment of leukodystrophies

(2019) Marjo S van der Knaap et al.   LANCET NEUROLOGY

Heterozygous Variants in the Mechanosensitive Ion Channel TMEM63A Result in Transient Hypomyelination during Infancy

(2019) Huifang Yan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

(2018) Matti Myllykoski et al.   JOURNAL OF NEUROCHEMISTRY

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

(2018) Ana Mendanha Falcão et al.   NATURE MEDICINE

Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

(2018) Mateusz C. Ambrozkiewicz et al.   NEURON

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The logistics of myelin biogenesis in the central nervous system

(2017) Nicolas Snaidero et al.   GLIA

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

(2017) Nicolas Snaidero et al.   Cell Reports

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

(2017) Arne Raasakka et al.   Scientific Reports

Label-free quantification in ion mobility–enhanced data-independent acquisition proteomics

(2016) Ute Distler et al.   Nature Protocols

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination

(2016) Jose Luis Olmos-Serrano et al.   NEURON

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

(2016) Hyun-Jeong Yang et al.   Nature Communications

The transcriptome of mouse central nervous system myelin

(2016) Sudhir Thakurela et al.   Scientific Reports

Metabolism and functions of lipids in myelin

(2015) Sebastian Schmitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Claudin-11 Tight Junctions in Myelin Are a Barrier to Diffusion and Lack Strong Adhesive Properties

(2015) Andrew R. Denninger et al.   BIOPHYSICAL JOURNAL

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder

(2015) Alexander Lossos et al.   BRAIN

How to make an oligodendrocyte

(2015) S. A. Goldman et al.   DEVELOPMENT

CNS Myelin Wrapping Is Driven by Actin Disassembly

(2015) J. Bradley Zuchero et al.   DEVELOPMENTAL CELL

Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System

(2015) Schanila Nawaz et al.   DEVELOPMENTAL CELL

The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry

(2015) H.-Christian von Büdingen et al.   JOURNAL OF CELL BIOLOGY

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(2015) Christoph Ott et al.   MOLECULAR MEDICINE

Cell type– and brain region–resolved mouse brain proteome

(2015) Kirti Sharma et al.   NATURE NEUROSCIENCE

In-depth evaluation of software tools for data-independent acquisition based label-free quantification

(2015) Jörg Kuharev et al.   PROTEOMICS

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development

(2015) Stefanie Giera et al.   Nature Communications

The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA

(2015) Sarah D. Ackerman et al.   Nature Communications

Myelination of the Nervous System: Mechanisms and Functions

(2014) Klaus-Armin Nave et al.   Annual Review of Cell and Developmental Biology

Biomedical applications of ion mobility-enhanced data-independent acquisition-based label-free quantitative proteomics

(2014) Ute Distler et al.   Expert Review of Proteomics

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

(2013) Cas Simons et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular evolution of myelin basic protein, an abundant structural myelin component

(2013) Schanila Nawaz et al.   GLIA

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

(2013) Patricia de Monasterio-Schrader et al.   GLIA

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

(2013) Hauke B. Werner et al.   GLIA

Oligodendrocyte Lineage Cells Contribute Unique Features to Rett Syndrome Neuropathology

(2013) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics

(2013) Ute Distler et al.   NATURE METHODS

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

An automated in-gel digestion/iTRAQ-labeling workflow for robust quantification of gel-separated proteins

(2013) Carla Schmidt et al.   PROTEOMICS

Critical assessment of proteome-wide label-free absolute abundance estimation strategies

(2013) Erik Ahrné et al.   PROTEOMICS

Systematic approaches to central nervous system myelin

(2012) Patricia de Monasterio-Schrader et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipidome and proteome map of myelin membranes

(2012) Gopakumar Gopalakrishnan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis

(2011) Natalia Manrique-Hoyos et al.   ANNALS OF NEUROLOGY

Less label, more free: Approaches in label-free quantitative mass spectrometry

(2011) Karlie A. Neilson et al.   PROTEOMICS

A proteome map of axoglial specializations isolated and purified from human central nervous system

(2010) Ajit S. Dhaunchak et al.   GLIA

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1

(2009) Julia M. Edgar et al.   GLIA

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

(2009) S. Nawaz et al.   JOURNAL OF NEUROSCIENCE

The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia

(2009) Anke Schardt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Myelin Proteomics: Molecular Anatomy of an Insulating Sheath

(2009) Olaf Jahn et al.   MOLECULAR NEUROBIOLOGY

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination

(2009) Ying Chen et al.   NATURE NEUROSCIENCE

Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection

(2009) Wiebke Möbius et al.   Neuron Glia Biology

Human myelin proteome and comparative analysis with mouse myelin

(2009) A. Ishii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Hsp60 Chaperonopathy Causes an Autosomal-Recessive Neurodegenerative Disorder Linked to Brain Hypomyelination and Leukodystrophy

(2008) Daniella Magen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myelin Basic Protein as a “PI(4,5)P2-Modulin”: A New Biological Function for a Major Central Nervous System Protein†

(2008) Abdiwahab A. Musse et al.   BIOCHEMISTRY

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling

(2008) Angelika Kippert et al.   BMC NEUROSCIENCE

Identification ofTmem10/Opalinas an oligodendrocyte enriched gene using expression profiling combined with genetic cell ablation

(2008) Neev Golan et al.   GLIA