4.4 Article

The Application of Chitosan and Its Derivatives as Nanosized Carriers for the Delivery of Chemical Drugs and Genes or Proteins

Journal

CURRENT DRUG TARGETS
Volume 17, Issue 7, Pages 811-816

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389450116666151019100106

Keywords

Polysaccharides; carriers; drug delivery; chemical drugs; genes; proteins

Funding

  1. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
  2. Scientific and Technological Research Program of Chongqing Municipal Education Commission [KJ1400523]
  3. Foundation Project of Chongqing Normal University [14XYY020]
  4. Chongqing Research Program of Basic Research and Frontier Technology [cstc2015jcyjA10054]
  5. Chongqing Postgraduate's Research and Innovation Project [CYS15153]
  6. Chongqing University Students' Training Project of Innovation & Undertaking, China [20151063 7072]

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The carrier technology provides an intelligent approach for drug delivery by entrapping the drug into a carrier, such as nanoparticles, microspheres, hydrogels, and so on, which can increase the bioavailability of drug, enhance targeting, reduce toxicity and side effects of drug. The polysaccharides, e.g., chitosan and its derivatives, as carriers for delivery of chemical drugs and genes or proteins were summed up herein.

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