Journal
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Volume 56, Issue 5, Pages 773-776Publisher
WILEY
DOI: 10.1002/uog.22189
Keywords
coagulopathy; COVID-19; placental pathology; pregnancy; SARS-CoV-2
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We report a case of a pregnant woman with COVID-19 who developed coagulopathy in the absence of severe clinical symptoms. A polymerase chain reaction test of a vaginal swab was positive for SARS-CoV-2 RNA, suggesting a possibility of perinatal transmission. Cesarean delivery was performed because of a non-reassuring fetal heart rate; the placenta showed increased perivillous fibrin deposition and intervillositis. Moreover, placental infection with SARS-CoV-2 was demonstrated by placental immunostaining. The findings suggest a possible relationship between placental fibrin deposition and chronic and acute intervillositis, non-reassuring fetal heart rate and coagulopathy in pregnant women with COVID-19. (c) 2020 The Authors.Ultrasound in Obstetrics & Gynecologypublished by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
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