Journal
THORAX
Volume 75, Issue 12, Pages 1116-1118Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/thoraxjnl-2020-215577
Keywords
viral infection; ARDS; imaging; CT MRI etc; histology; cytology
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In December 2019, an outbreak of severe acute respiratory syndrome associated to SARS-CoV2 was reported in Wuhan, China. To date, little is known on histopathological findings in patients infected with the new SARS-CoV2. Lung histopathology shows features of acute and organising diffuse alveolar damage. Subtle cellular inflammatory infiltrate has been found in line with the cytokine storm theory. Medium-size vessel thrombi were frequent, but capillary thrombi were not present. Despite the elevation of biochemical markers of cardiac injury, little histopathological damage could be confirmed. Viral RNA from paraffin sections was detected at least in one organ in 90% patients.
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