Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction

Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection

(2016) J. Stuart Elborn et al.   Journal of Cystic Fibrosis

Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy

(2015) André M. Cantin et al.   Journal of Cystic Fibrosis

Distinct Cellular Sources of Hepoxilin A3and Leukotriene B4Are Used To Coordinate Bacterial-Induced Neutrophil Transepithelial Migration

(2014) Michael A. Pazos et al.   JOURNAL OF IMMUNOLOGY

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Cathelicidin LL-37: An Antimicrobial Peptide with a Role in Inflammatory Skin Disease

(2012) Markus Reinholz et al.   Annals of Dermatology

LTB4 Is a Signal-Relay Molecule during Neutrophil Chemotaxis

(2012) Philippe V. Afonso et al.   DEVELOPMENTAL CELL

Safety and early treatment effects of the CXCR2 antagonist SB-656933 in patients with cystic fibrosis

(2012) Richard B. Moss et al.   Journal of Cystic Fibrosis

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and Fc R signaling

(2012) C. D. Sadik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

(2011) Flávio A. Amaral et al.   ARTHRITIS AND RHEUMATISM

Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation

(2011) Christian D. Sadik et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of LTB4 in the pathogenesis of elastase-induced murine pulmonary emphysema

(2010) Y. Michael Shim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Leukotriene A4Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness

(2010) Navin L. Rao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting neutrophil elastase in cystic fibrosis

(2008) Emer Kelly et al.   EXPERT OPINION ON THERAPEUTIC TARGETS