Article
Environmental Sciences
Akihiko Hata, Yuno Meuchi, Miaomiao Liu, Shotaro Torii, Hiroyuki Katayama
Summary: Polymerase chain reaction (PCR) is widely used for monitoring pathogenic viruses in water environments. This study characterized and validated methods for quantifying active viruses and indicators in surface water. The study found that CDDP-RT-qPCR can be used for quantifying virus concentrations with higher detection frequencies than culture assays, but it may overestimate the activity of the virus.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Vu Duc Canh, Shotaro Torii, Hiroaki Furumai, Hiroyuki Katayama
Summary: The study applied a new method (SD-CDDP-(RT-)qPCR) to detect viruses in surface water and tap water in the Kanto region of Japan. The results showed that PMMoV was more frequently detected in surface water, while most target viruses were not detected in tap water. SD-CDDP-(RT-)qPCR revealed a higher proportion of intact PMMoV and a lower proportion of intact human pathogenic viruses.
Article
Agriculture, Dairy & Animal Science
Gabriele Ratti, Angelica Stranieri, Alessia Giordano, Maurizio Oltolina, Eleonora Bonacina, William Magnone, Manuel Morici, Giuliano Ravasio, Saverio Paltrinieri, Stefania Lauzi
Summary: This study aimed to assess the prevalence of feline coronavirus in captive non-domestic felids from Northern Italy. The overall prevalence was found to be 7.9%, with the virus detected in tiger cubs. The results highlight the need for control programs to prevent the devastating effects of the virus on animal welfare and conservation programs.
Article
Engineering, Environmental
Kyungho Kim, Narayanan Jothikumar, Anindito Sen, Jennifer L. Murphy, Shankararaman Chellam
Summary: The study demonstrates that both conventional FeCl3 coagulation and Fe(0) electrocoagulation are effective in removing and inactivating the coronavirus surrogate phi 6 in water treatment processes, with the hydrophobicity of phi 6 and its interaction with iron (hydr)oxide playing key roles. Oxidative damage and envelope rupture during electrocoagulation lead to virus inactivation, highlighting the importance in controlling enveloped viruses during surface water treatment.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Infectious Diseases
Sigitas Paliksa, Mantvydas Lopeta, Jonas Belevicius, Vaida Kurmauskaite, Ieva Asmenaviciute, Laura Pereckaite, Astra Vitkauskien, Ieva Baliutyte, Monika Valentaite, Aukse Mickiene, Julius Gagilas
Summary: The study compared SARS-CoV-2 RNA detection results of saliva and NP swab samples, showing good concordance and correlation between the two sample types. The saliva collection method demonstrated lower Ct variation for internal control detection, suggesting it is a robust and promising alternative for non-invasive COVID-19 screening.
INFECTION AND DRUG RESISTANCE
(2021)
Article
Biochemical Research Methods
Priscilla Stela Santana de Oliveira, Barbara de Oliveira Silva, Romulo Pessoa e Silva, Lilia Vieira Galdino, Vanessa Mylenna Florencio de Carvalho, Anderson Rodrigues de Almeida, Michelle Melgarejo da Rosa, Moacyr Jesus Barreto de Melo Rego, Maira Galdino da Rocha Pitta, Michelly Cristiny Pereira
Summary: Maintaining the quality and viability of SARS-Cov-2 RNA samples is crucial for laboratories and researchers to identify the predominant strain of the virus in a region. A study found that after one year, RNA extracted from human nasopharyngeal specimens can still detect SARS-CoV-2 genes with minor changes.
JOURNAL OF VIROLOGICAL METHODS
(2022)
Article
Infectious Diseases
Maria-Theresia Gekenidis, Fiona Walsh, David Drissner
Summary: This study analyzed the contribution of surface and tap water to the resistome of overhead-irrigated chive plants and found that water quality significantly affects the resistome of irrigated produce. Water played a major role in antibiotic resistance gene enrichment, especially beta-lactam ARGs and MGEs. Various antibiotic resistance genes were identified in both water sources and chive plants, with bla(KPC) detected at high levels in both.
Article
Environmental Sciences
Matthew T. Flood, Nishita D'Souza, Joan B. Rose, Tiong Gim Aw
Summary: Wastewater surveillance of SARS-CoV-2 is essential for understanding the spread of COVID-19 in communities. Evaluating different concentration methods such as PEG precipitation and PCR techniques like RT-ddPCR can provide effective detection and quantification of SARS-CoV-2 genetic markers in wastewater matrices.
FOOD AND ENVIRONMENTAL VIROLOGY
(2021)
Article
Chemistry, Analytical
Lianhua Dong, Junbo Zhou, Chunyan Niu, Quanyi Wang, Yang Pan, Sitong Sheng, Xia Wang, Yongzhuo Zhang, Jiayi Yang, Manqing Liu, Yang Zhao, Xiaoying Zhang, Tao Zhu, Tao Peng, Jie Xie, Yunhua Gao, Di Wang, Xinhua Dai, Xiang Fang
Summary: The COVID-19 outbreak caused by a novel Coronavirus has spread globally. Current gold standard RT-qPCR for SARS-CoV-2 diagnosis shows varying sensitivity, highlighting the need for more accurate methods. A study on RT-dPCR demonstrated significant improvement in detection sensitivity, particularly for asymptomatic patients, making it a highly accurate method for screening suspected cases.
Article
Infectious Diseases
Lauren Hubert Jaeger, Thiago Cesar Nascimento, Fabiola Dutra Rocha, Fernanda Maria Pinto Vilela, Ana Paula do Nascimento Duque, Livia Mara Silva, Lorena Rodrigues Riani, Joao Paulo Moreira, Jessica Mara de Assis Chagas, Thamiris Vilela Pereira, Carmen Gomide Pinto Perches, Aripuana Sakurada Aranha Watanabe, Lyderson Facio Viccini, Marcelo Silva Silverio, Jose Otavio Amaral Correa, Olavo dos Santos Pereira-Junior, Frederico Pittella
Summary: The study reported the formation of dimers in the diagnostic primers-probe set for COVID-19 and proposed alternatives to reduce dimerization events. By optimizing RT-qPCR parameters, the late unspecific amplifications in negative samples and no-template controls were successfully decreased.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Plant Sciences
Katarina Luksic, Ana Mucalo, Ana Smolko, Lidija Brkljacic, Luka Marinov, Katarina Hancevic, Maja Ozretic Zokovic, Marijan Bubola, Edi Maletic, Jasminka Karoglan Kontic, Marko Karoglan, Branka Salopek-Sondi, Goran Zdunic
Summary: The biochemical response and gene expression in different grapevine cultivars to water deficit were investigated in this study. The results showed that water deficit significantly increased abscisic acid, salicylic acid, and proline accumulation in the leaves of stressed genotypes. Lipid peroxidation was lower in stressed plants after nine days of water deficit. The cultivar 'Istrian Malvasia' showed the highest and earliest increase in ABA levels, and 'Grasevina' differed significantly from other genotypes in SA content.
Article
Food Science & Technology
Chenang Lyu, Feifeng Lu, Zhentao Shi, Dapeng Wang
Summary: The study developed an ISC-RT-qPCR assay for detecting encapsulated RVA in oysters with higher sensitivity and accuracy than RT-qPCR. When applied to oysters collected from four different farms, ISC-RT-qPCR showed a higher detection rate of RVA compared to RT-qPCR, indicating its potential as a better method for disease monitoring and control.
Article
Environmental Sciences
Mary Jean See, David C. Bencic, Robert W. Flick, Jim Lazorchak, Adam D. Biales
Summary: This study characterized the VTG protein in male fathead minnow mucus compared to plasma and liver mRNA. The results showed that the induction kinetics of VTG protein concentration in mucus and plasma were similar, with a significant increase detected after 2 days of exposure in the mucus-based assay and after 7 days in the plasma-based assay.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Environmental
Ananda Tiwari, Anssi Lipponen, Anna-Maria Hokajarvi, Oskari Luomala, Anniina Sarekoski, Annastiina Rytkonen, Pamela Osterlund, Haider Al-Hello, Aapo Juutinen, Ilkka T. Miettinen, Carita Savolainen-Kopra, Tarja Pitkanen
Summary: Wastewater-based surveillance is a cost-effective method for monitoring the COVID-19 pandemic at a population level. This study in Finland monitored SARS-CoV-2 RNA in wastewater samples from multiple treatment plants over a 10-month period. The detection rate of SARS-CoV-2 RNA in wastewater was 79%, and the surveillance proved to be a reliable indicator for COVID-19 incidence, independent of clinical testing strategies or individual testing willingness.
Article
Fisheries
Lisa-Victoria Bernhardt, Mette Myrmel, Atle Lillehaug, Lars Qviller, Simon Chioma Weli
Summary: This study developed and optimized a method for detecting SAV3 in water, showing the potential for serving as an alternative surveillance method for SAV in Norwegian Atlantic salmon farms. The method was tested through a cohabitant challenge trial and demonstrated a significant positive correlation between SAV3 in tank water concentrates and fish organ tissue samples.
DISEASES OF AQUATIC ORGANISMS
(2021)
Article
Environmental Sciences
Sofia Albolafio, Alicia Marin, Ana Allende, Francisca Garcia, Pedro J. Simon-Andreu, Manuel Abellan Soler, Maria Gil
Article
Infectious Diseases
Paula de Michelena, Ignacio Torres, Enric-Cuevas Ferrando, Beatriz Olea, Fernando Gonzalez-Candelas, Gloria Sanchez, David Navarro
Summary: This study compared the RNA loads of severe acute respiratory syndrome coronavirus 2 in nasopharyngeal specimens collected from patients infected with breakthrough COVID-19 caused by the Omicron variant and the Delta variant. The results showed that the viral RNA loads were significantly higher for the Omicron variant compared to the Delta variant.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Article
Biotechnology & Applied Microbiology
Pilar Truchado, Marisa Gomez-Galindo, M. Gil, Ana Allende
Summary: Some water disinfection treatments used in the fresh-cut industry can lead to the formation of viable but non-culturable (VBNC) cells. This study found that VBNC cells can cross-contaminate leafy greens during washing but have low resuscitation capacity during storage.
Article
Microbiology
Maria Costafreda, Silvia Sauleda, Mar Riveiro-Barciela, Angie Rico, Meritxell Llorens-Revull, Susana Guix, Rosa M. Pinto, Albert Bosch, Francisco Rodriguez-Frias, Ariadna Rando, Maria Piron, Marta Bes
Summary: Different outcomes of HEV infection are associated with specific dysregulation of microRNAs, which can serve as biomarkers for HEV infection outcomes and contribute to improving the clinical management of hepatitis E patients. This study provides new insights into HEV pathogenesis and potential targets for antiviral treatments.
MICROBIOLOGY SPECTRUM
(2023)
Article
Food Science & Technology
Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez-Ordonez, Declan Bolton, Sara Bover-Cid, Marianne Chemaly, Alessandra De Cesare, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernandez Escamez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Just Vlak, Fulvio Barizzone, Sandra Correia, Lieve Herman
Summary: The qualified presumption of safety (QPS) approach is a regularly updated generic pre-evaluation of the safety of microorganisms in the food or feed chains. It is used to support the work of EFSA's Scientific Panels. In this study, 52 microorganisms were evaluated between April and September 2022.
Article
Food Science & Technology
Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez-Ordonez, Sara Bover-Cid, Marianne Chemaly, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Bojan Blagojevic, Inge Van Damme, Michaela Hempen, Winy Messens, Declan Bolton
Summary: This study examines the impact of dry-ageing of beef and wet-ageing of beef, pork, and lamb on microbiological hazards and spoilage bacteria, and describes current practices. It differentiates between 'standard fresh' and wet-aged meat based on duration. The study collates data on key parameters (time, temperature, pH, and a(w)) using a literature survey and questionnaires. Various microbiological hazards and spoilage bacteria are identified in aged meats, and methods to prevent their growth are discussed. The study concludes that ageing meat under defined and controlled conditions can achieve similar or lower levels of microbiological hazards and spoilage bacteria than standard fresh meat preparation.
Article
Biotechnology & Applied Microbiology
Maria T. Brandl, Renata Ivanek, Ana Allende, Daniel S. Munther
Summary: Weather factors greatly influence bacterial behavior on plants, and a novel model based on weather factors and bacterial state was developed to predict population dynamics on leafy vegetables. The model accurately predicted population sizes of pathogenic E. coli and S. enterica on lettuce and cilantro leaves under various conditions. The model showed potential in predicting contamination risk in the field, highlighting the importance of weather-based models in ensuring microbial safety of produce. Rating: 9/10
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Engineering, Environmental
Ines Giron-Guzman, Azahara Diaz-Reolid, Pilar Truchado, Albert Carcereny, David Garcia-Pedemonte, Bruno Hernaez, Albert Bosch, Rosa Maria Pinto, Susana Guix, Ana Allende, Antonio Alcami, Alba Perez-Cataluna, Gloria Sanchez
Summary: Monkeypox virus (MPXV) DNA was detected in various samples including saliva, semen, urine, and fecal samples besides nasopharyngeal swabs. The study analyzed the presence of MPXV DNA in wastewater collected from different areas of Spain using a surveillance network. The results showed that MPXV DNA could be consistently detected in longitudinal wastewater samples from different treatment plants, indicating the possibility of underestimated cases and frequent asymptomatic infections.
Article
Food Science & Technology
Irene Falco, Juan A. Tudela, Natalia Hernandez, Alba Perez-Cataluna, Miriam R. Garcia, Pilar Truchado, Agustin Garrido, Ana Allende, Gloria Sanchez, Maria Isabel Gil
Summary: This study evaluates the disinfection efficacy of chlorine, chlorine dioxide, and peracetic acid on human enteric viruses in produce process water. The results showed that chlorine and chlorine dioxide can effectively inactivate bacteria and coliphages, but had limited efficacy against hepatitis A virus. Peracetic acid was unable to completely inactivate viruses in any type of water. Therefore, it is important to select the most effective sanitizer and ensure sufficient concentration and contact time to prevent viral cross-contamination during washing operations.
Article
Engineering, Environmental
Mattia Mattei, Rosa M. Pinto, Susana Guix, Albert Bosch, Alex Arenas
Summary: We analyzed SARS-CoV-2 genome copies in Catalonia's wastewater and developed a mathematical model to estimate the number of infections and the temporal relationship between reported and unreported cases. Samples from 16 wastewater treatment plants were used in an epidemiological model, showing a strong correlation between genome copies and reported cases with a delay of 8.8 days. The model estimated a higher infection rate (53%) compared to the reported cases (19%), indicating under-reporting in November and December 2021. The maximum genome copies shed in feces by an infected individual ranged from 1.4 x 108 gc/g to 4.4 x 108 gc/g. This study highlights the potential of using wastewater data as an early indicator for new infections and provides a framework for integrating such data into epidemiological models.
Article
Virology
Jose A. Ferez, Enric Cuevas-Ferrando, Maria Ayala-San Nicolas, Pedro Simon J. Andreu, Roman Lopez, Pilar Truchado, Gloria Sanchez, Ana Allende
Summary: This study analyzed and tracked the SARS-CoV-2 virus in the southeast of Spain using wastewater-based epidemiology. The results showed that the virus levels in wastewater samples were correlated with the number of cases in the population, and variant occurrences matched clinical data. Machine learning methods were also applied to identify virus variants in different wastewater samples. This study provides a preliminary evaluation of circulating variants in a specific population at a specific time point.
Article
Food Science & Technology
Marisa Gomez-Galindo, Pilar Truchado, Ana Allende, Maria I. Gil
Summary: A commercial phage biocontrol has been proven effective in improving fresh produce safety, but challenges in industrial application need to be overcome. Validating studies conducted in Spain and Denmark confirmed the suitability of the biocontrol treatment method. When applied properly, the treatment did not affect the quality of shredded iceberg lettuce.
Article
Food Science & Technology
Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez-Ordonez, Declan Bolton, Sara Bover-Cid, Marianne Chemaly, Alessandra de Cesare, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernandez Escamez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Just Vlak, Fulvio Barizzone, Michaela Hempen, Sandra Correia, Lieve Herman
Summary: The qualified presumption of safety (QPS) is a generic pre-assessment method that supports the work of EFSA's Scientific Panels by evaluating the safety of microorganisms in the food or feed chains. The evaluation is based on the body of knowledge and safety concerns of the microorganisms. Some strains, such as filamentous fungi, bacteriophages, oomycetes, and certain bacteria, are excluded from the QPS assessment due to their potentially harmful traits. The QPS list is regularly reviewed and updated, and new TUs can receive QPS status if they meet the necessary qualifications.
Article
Food Science & Technology
Maria Isabel Gil, Pilar Truchado, Juan Antonio Tudela, Ana Allende
Summary: This study assessed the environmental contamination in fresh-cut facilities, focusing on areas that required further investigation. The prevalence of L. monocytogenes and Listeria spp. was high in cut vegetables, cut fruits, and prepared salads. The study highlighted the importance of selecting appropriate detection methods and including food contact surfaces in environmental monitoring.
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
