BDNF and JNK Signaling Modulate Cortical Interneuron and Perineuronal Net Development: Implications for Schizophrenia-Linked 16p11.2 Duplication Syndrome

Single-nucleus RNA sequencing of mouse auditory cortex reveals critical period triggers and brakes

(2020) Brian T. Kalish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia

(2020) Greg C. Bristow et al.   Cell Reports

Psychiatric disorders in children with 16p11.2 deletion and duplication

(2019) Maria Niarchou et al.   Translational Psychiatry

Structural maturation of cortical perineuronal nets and their perforating synapses revealed by superresolution imaging

(2019) Yaron M. Sigal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

(2019) James W. Fawcett et al.   NATURE REVIEWS NEUROSCIENCE

Psychotic symptoms in 16p11.2 copy‐number variant carriers

(2019) Amandeep Jutla et al.   Autism Research

Suppression of Parvalbumin Interneuron Activity in the Prefrontal Cortex Recapitulates Features of Impaired Excitatory/Inhibitory Balance and Sensory Processing in Schizophrenia

(2019) Oana Toader et al.   SCHIZOPHRENIA BULLETIN

Distortion of protein analysis in primary neuronal cultures by serum albumin from culture medium: A methodological approach to improve target protein quantification

(2018) Ashleigh Willis et al.   JOURNAL OF NEUROSCIENCE METHODS

Prefrontal cortical parvalbumin and somatostatin expression and cell density increase during adolescence and are modified by BDNF and sex

(2018) X. Du et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

(2018) Melanie Richter et al.   MOLECULAR PSYCHIATRY

PV Interneurons: Critical Regulators of E/I Balance for Prefrontal Cortex-Dependent Behavior and Psychiatric Disorders

(2018) Brielle R. Ferguson et al.   Frontiers in Neural Circuits

A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies

(2018) Caterina Giacomini et al.   Acta Neuropathologica Communications

A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme

(2018) Chiara Magri et al.   Scientific Reports

Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights

(2018) Itaru Kushima et al.   Cell Reports

Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells

(2017) Chuay-Yeng Koo et al.   MOLECULAR CANCER THERAPEUTICS

Extracellular matrix alterations in the ketamine model of schizophrenia

(2017) Gabriela Matuszko et al.   NEUROSCIENCE

Rare and common variants at 16p11.2 are associated with schizophrenia

(2017) Hong Chang et al.   SCHIZOPHRENIA RESEARCH

Hyaluronan synthesis by developing cortical neurons in vitro

(2017) Tania M. Fowke et al.   Scientific Reports

Chondroitin Sulfate Is Required for Onset and Offset of Critical Period Plasticity in Visual Cortex

(2017) Xubin Hou et al.   Scientific Reports

Molecular heterogeneity of aggrecan-based perineuronal nets around five subclasses of parvalbumin-expressing neurons in the mouse hippocampus

(2016) Jun Yamada et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Schizophrenia

(2016) Michael J Owen et al.   LANCET

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

(2016) Christian R Marshall et al.   NATURE GENETICS

Altering the course of schizophrenia: progress and perspectives

(2016) Mark J. Millan et al.   NATURE REVIEWS DRUG DISCOVERY

Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub

(2016) Katherine D. Blizinsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline

(2016) R.L. Openshaw et al.   PSYCHOPHARMACOLOGY

The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity

(2016) F. de Winter et al.   NEURAL PLASTICITY

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

(2015) Sujeong Yang et al.   EXPERIMENTAL NEUROLOGY

The thalamic reticular nucleus: A functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery

(2015) Judith A Pratt et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

(2015) Martine N. Manuel et al.   Frontiers in Cellular Neuroscience

Compartmentalization of GABA Synthesis by GAD67 Differs between Pancreatic Beta Cells and Neurons

(2015) Jamil Kanaani et al.   PLoS One

Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate

(2014) S. Miyata et al.   JOURNAL OF BIOCHEMISTRY

Jnk1 Activity is Indispensable for Appropriate Cortical Interneuron Migration in the Developing Cerebral Cortex

(2014) J. J. Riches et al.   JOURNAL OF NEUROSCIENCE

Cortical Interneurons Require Jnk1 to Enter and Navigate the Developing Cerebral Cortex

(2014) A. K. Myers et al.   JOURNAL OF NEUROSCIENCE

Equalizing excitation–inhibition ratios across visual cortical neurons

(2014) Mingshan Xue et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Early depolarizing GABA controls critical-period plasticity in the rat visual cortex

(2014) Gabriele Deidda et al.   NATURE NEUROSCIENCE

Nuclear and cytosolic JNK signalling in neurons

(2014) Eleanor T. Coffey   NATURE REVIEWS NEUROSCIENCE

Does rare matter? Copy number variants at 16p11.2 and the risk of psychosis: A systematic review of literature and meta-analysis

(2014) Giovanni Giaroli et al.   SCHIZOPHRENIA RESEARCH

Developmental Pattern of Perineuronal Nets in the Human Prefrontal Cortex and Their Deficit in Schizophrenia

(2013) Sarah A. Mauney et al.   BIOLOGICAL PSYCHIATRY

The Penetrance of Copy Number Variations for Schizophrenia and Developmental Delay

(2013) George Kirov et al.   BIOLOGICAL PSYCHIATRY

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

GAD67 Deficiency in Parvalbumin Interneurons Produces Deficits in Inhibitory Transmission and Network Disinhibition in Mouse Prefrontal Cortex

(2013) M. S. Lazarus et al.   CEREBRAL CORTEX

Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains

(2013) Gunnar Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

(2013) C. Romberg et al.   JOURNAL OF NEUROSCIENCE

Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to parvalbumin

(2013) J. Yamada et al.   NEUROSCIENCE

Involvement of TrkB- and p75NTR-signaling pathways in two contrasting forms of long-lasting synaptic plasticity

(2013) Shigeo Sakuragi et al.   Scientific Reports

Regulating Critical Period Plasticity: Insight from the Visual System to Fear Circuitry for Therapeutic Interventions

(2013) Elisa M. Nabel et al.   Frontiers in Psychiatry

The perineuronal net and the control of CNS plasticity

(2012) Difei Wang et al.   CELL AND TISSUE RESEARCH

Discovery of Potent and Selective Covalent Inhibitors of JNK

(2012) Tinghu Zhang et al.   CHEMISTRY & BIOLOGY

Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia

(2012) C. L. Winchester et al.   HUMAN MOLECULAR GENETICS

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex

(2012) Froylan Calderon de Anda et al.   NATURE NEUROSCIENCE

Extracellular matrix and perineuronal nets in CNS repair

(2011) Jessica C.F. Kwok et al.   Developmental Neurobiology

PSD-95 and PSD-93 Play Critical But Distinct Roles in Synaptic Scaling Up and Down

(2011) Q. Sun et al.   JOURNAL OF NEUROSCIENCE

The role of BDNF in the pathophysiology and treatment of schizophrenia

(2011) Gabriela Favalli et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Extracellular matrix abnormalities in schizophrenia

(2011) Sabina Berretta   NEUROPHARMACOLOGY

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

(2011) G. Horev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

(2011) David A. Lewis et al.   TRENDS IN NEUROSCIENCES

Brain-derived neurotrophic factor levels in schizophrenia: a systematic review with meta-analysis

(2010) M J Green et al.   MOLECULAR PSYCHIATRY

The Thalamic Reticular Nucleus and Schizophrenia

(2010) F. Ferrarelli et al.   SCHIZOPHRENIA BULLETIN

Copy Number Variation in Human Health, Disease, and Evolution

(2009) Feng Zhang et al.   Annual Review of Genomics and Human Genetics

Transcriptional and Electrophysiological Maturation of Neocortical Fast-Spiking GABAergic Interneurons

(2009) B. W. Okaty et al.   JOURNAL OF NEUROSCIENCE

Microduplications of 16p11.2 are associated with schizophrenia

(2009) Shane E McCarthy et al.   NATURE GENETICS

Adult and Embryonic GAD Transcripts Are Spatiotemporally Regulated during Postnatal Development in the Rat Brain

(2009) Anke Popp et al.   PLoS One

Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK

(2008) Gareth M Thomas et al.   EMBO JOURNAL

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE