Kahweol activates the Nrf2/HO-1 pathway by decreasing Keap1 expression independently of p62 and autophagy pathways

The effects of kahweol, a diterpene present in coffee, on the mitochondria of the human neuroblastoma SH-SY5Y cells exposed to hydrogen peroxide

(2019) Cristina Ribas Fürstenau et al.   TOXICOLOGY IN VITRO

Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance

(2018) Azhwar Raghunath et al.   Cancers

Suppression of PMA-induced human fibrosarcoma HT-1080 invasion and metastasis by kahweol via inhibiting Akt/JNK1/2/p38 MAPK signal pathway and NF-κB dependent transcriptional activities

(2018) Jae Ho Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway

(2017) Hye-Young Seo et al.   Oncotarget

Role of Oxidative Stress in Liver Health and Disease

(2016) Pablo Muriel et al.   Oxidative Medicine and Cellular Longevity

KEAP1–NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity

(2015) Matthew Dodson et al.   BIOCHEMICAL JOURNAL

The Role of Oxidative Stress and Antioxidants in Liver Diseases

(2015) Sha Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Insights on the antitumor effects of kahweol on human breast cancer: Decreased survival and increased production of reactive oxygen species and cytotoxicity

(2014) Casimiro Cárdenas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of Nrf2 in chronic liver disease

(2014) Wei Tang   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress as a crucial factor in liver diseases

(2014) Halina Cichoż-Lach   WORLD JOURNAL OF GASTROENTEROLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Mitochondria Sentencing About Cellular Life and Death: A Matter of Oxidative Stress

(2012) Nadezda Apostolova et al.   CURRENT PHARMACEUTICAL DESIGN

Keap1 degradation by autophagy for the maintenance of redox homeostasis

(2012) K. Taguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation

(2012) Kai Connie Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Correction: Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene

(2011) Casimiro Cárdenas et al.   PLoS One

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress

(2008) Yong Pil Hwang et al.   FEBS LETTERS