Review
Biotechnology & Applied Microbiology
Shaodong Wei, Martin Iain Bahl, Simon Mark Dahl Baunwall, Christian Lodberg Hvas, Tine Rask Licht
Summary: This paper lists various types of dysbiosis indexes identified in the literature, introduces their methodology, categorizes them, and discusses their potential descriptive and clinical applications as well as their limitations. The focus is on the methodological approaches available to determine and quantify the dysbiosis condition, rather than on the implications of dysbiosis for disease.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Kristopher D. Parker, Akhilendra K. Maurya, Hend Ibrahim, Sangeeta Rao, Petronella R. Hove, Dileep Kumar, Rama Kant, Bupinder Raina, Rajesh Agarwal, Kristine A. Kuhn, Komal Raina, Elizabeth P. Ryan
Summary: The study demonstrates that modified gut microbiota from humans consuming rice bran can protect mice from colon carcinogenesis, with specific microbial communities associated with colon health. The findings suggest that integrated dietary-FMT intervention strategies could be effective for colorectal cancer control, treatment, and prevention.
Article
Agriculture, Multidisciplinary
Humphrey A. Mabwi, Hee Ju Lee, Emmanuel Hitayezu, Intan Rizki Mauliasari, Cheol-Ho Pan, Kilaza Samson Mwaikono, Erick V. G. Komba, Choong-Gu Lee, Kwang Hyun Cha
Summary: The study found that emodin has effects on the gut microbiota, promoting the growth of beneficial bacteria and inhibiting the growth of major bacterial groups. It also induces the production of anti-inflammatory immune cells, suggesting its potential use in modulating the gut microbiota and improving health.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Kaili Wang, Xiufang Xia, Lina Sun, Hui Wang, Qiu Li, Zhuo Yang, Jing Ren
Summary: The gut microbiota is important for infants' growth and development in early life. Breast milk microbiota influences the colonization and development of the infant's gut microbiota. In this study, we examined the microbial diversity and correlation between breast milk and infant gut by sequencing the microbiome in both human milk and infant stools. The results showed the presence of certain bacteria in both breast milk and infant feces, indicating their transfer from breast milk to the infant's gut.
Article
Food Science & Technology
LinShu Liu, Adrienne B. Narrowe, Jenni A. Firrman, Karley K. Mahalak, Jamshed T. Bobokalonov, Johanna M. S. Lemons, Kyle Bittinger, Scott Daniel, Ceylan Tanes, Lisa Mattei, Elliot S. Friedman, Jason W. Soares, Masuko Kobori, Wei-Bin Zeng, Peggy M. Tomasula
Summary: In this study, we examined the changes in the gut metabolome in response to the administration of Laticaseibacillus rhamnosus strain GG (LGG). The probiotics were added to the ascending colon region of a human intestinal microbial ecosystem simulator. The results showed that the changes in microbial community composition were associated with changes in metabolic output, revealing sequential amino acid metabolic pathways along the colonic tract.
Article
Immunology
Sahar Behboud, Kavous Solhjoo, Saiedeh Erfanian, Majid Pirestani, Amir Abdoli
Summary: This study found that asymptomatic Blastocystis infection could alter the composition of gut bacteria in healthy individuals, including upregulation of certain bacteria and downregulation of others.
MICROBIAL PATHOGENESIS
(2022)
Review
Immunology
Liliana Rojas-Velazquez, Patricia Moran, Angelica Serrano-Vazquez, Tobias Portillo-Bobadilla, Enrique Gonzalez, Horacio Perez-Juarez, Eric Hernandez, Oswaldo Partida-Rodriguez, Miriam Nieves-Ramirez, Angeles Padilla, Martha Zaragoza, Cecilia Ximenez
Summary: Blastocystis spp. is a unicellular organism found in the digestive tracts of various vertebrates. Recent studies suggest its involvement in the immune inflammatory response in the gut microbiome, generating an anti-inflammatory effect. However, its role as a pathogen or commensal organism is still debated.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Christen Rune Stensvold, Brede Aksdal Sorland, Rebecca P. K. D. Berg, Lee O'Brien Andersen, Mark van der Giezen, Joanna L. Bowtell, Ayman A. El-Badry, Salem Belkessa, Ozgur Kurt, Henrik Vedel Nielsen
Summary: Using metabarcoding and bioinformatics analyses, differences were identified in stool microbiota diversity between Blastocystis-positive and Blastocystis-negative individuals. Blastocystis carriers showed higher alpha diversity and enrichment of Firmicutes and Bacteroidetes at the phylum level, while non-carriers showed enrichment of Proteobacteria. The presence of certain genera also differed between carriers and non-carriers. Blastocystis-positive stools appeared to have gut microbiomes associated with eubiosis, while Blastocystis-negative stools showed similarities to dysbiosis-related microbiomes.
Review
Nutrition & Dietetics
Malgorzata Anna Marc, Rafal Jastrzab, Jennifer Mytych
Summary: This article summarizes the latest knowledge on the correlation between gut microbiota dysbiosis and neurodegenerative and brain-related diseases such as Alzheimer's and Parkinson's. It emphasizes the importance of gut-derived metabolites and gut metabolic status as key factors in gut-brain crosstalk and their impact on the severity of neural conditions.
Article
Veterinary Sciences
Chao Yan, Jinlong Xiao, Zhiwei Li, Hao Liu, Xinjie Zhao, Jian Liu, Siyu Chen, Xingbo Zhao
Summary: The study found that transferring fecal microbiota from aged broilers donors to recipients can improve body weight, behavior, intestinal development, and gut microbiota composition. Fearfulness was higher in the control group compared to the broiler recipient group, while intestinal development indicators were also higher in the BR group. Beta diversity of gut microbiota showed differences between the CK and BR groups.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Review
Food Science & Technology
Jorge Armando Jimenez-Avalos, Gerardo Arrevillaga-Boni, Lorena Gonzalez-Lopez, Zaira Yunuen Garcia-Carvajal, Marisela Gonzalez-Avila
Summary: A healthy Human Gut Microbial Ecosystem (HGME) is essential for the proper functioning of the body, with dysbiosis potentially leading to various disorders. Different methods such as diet, probiotics, antibiotics, and Fecal Microbiota Transplantation (FMT) can help restore or maintain the balance of Gut Microbiota (GM) populations. New approaches such as engineered nanomaterials, phagotherapy, antimicrobial peptides, non-antibiotic drugs, vaccines, and immunoglobulins are promising strategies for modulating HGME.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Parasitology
Lei Deng, Jonathan W. J. Lee, Kevin S. W. Tan
Summary: This study reveals the association between Blastocystis ST7 infection and decreased gut microbiota diversity and altered microbial structure in diarrheal patients. The gut microbiota composition of patients infected with ST7 differs significantly from those without Blastocystis infection.
PARASITES & VECTORS
(2022)
Article
Gastroenterology & Hepatology
Pajau Vangay, Tonya Ward, Sarah Lucas, Lalit K. Beura, Dominique Sabas, Max Abramson, Lisa Till, Susan L. Hoops, Purna Kashyap, Ryan C. Hunter, David Masopust, Dan Knights
Summary: In this study, the differential effects of human gut microbiota from the United States and rural Thailand on the murine gut mucosa and immune system were assessed. The results suggest that Western-associated human gut microbes contribute to a pro-inflammatory immune response.
Review
Anthropology
Katherine R. Amato, Rachel N. Carmody
Summary: This article summarizes the current understanding of the three-way interactions between the gut microbiota, human ecology, and human evolution. The review examines factors driving microbiome variation and comparative data from nonhuman primates, providing insights into microbial relationships with host ecology and evolution.
ANNUAL REVIEW OF ANTHROPOLOGY
(2023)
Article
Dermatology
Atiya Rungjang, Jitlada Meephansan, Sunchai Payungporn, Vorthon Sawaswong, Prangwalai Chanchaem, Purit Pureesrisak, Jongkonnee Wongpiyabovorn, Hok Bing Thio
Summary: There is a relationship between gut microbiota and psoriasis development and treatment response. This study analyzed the change in gut microbiota during narrowband ultraviolet B (NBUVB) therapy for psoriasis. The results showed that NBUVB therapy altered the gut microbiota of psoriasis patients and this change may have an impact on treatment response.
EXPERIMENTAL DERMATOLOGY
(2022)
Article
Infectious Diseases
Adriana Castillo-Castaneda, Luz H. Patino, Marina Munoz, Martha S. Ayala, Maryi Segura, Jessica Bautista, Maryia Shaban, Alberto Paniz-Mondolfi, Juan David Ramirez
Summary: This study used amplicon-based next-generation sequencing to identify visceral leishmaniasis (VL) aetiologic species in clinical samples. The results revealed co-infections of different Leishmania species in VL patients, highlighting the importance of understanding the biological, clinical, and epidemiological implications. The methodology used in this study demonstrates its potential usefulness in detecting trypanosomatid coinfections.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Virology
Angie L. Ramirez, Nicolas Luna, Luz H. Patino, Sergio Castaneda, Marina Munoz, Nathalia Ballesteros, Julie Perez, Camilo A. Correa-Cardenas, Maria Clara Duque, Claudia Mendez, Carolina Oliveros, Alberto E. Paniz-Mondolfi, Juan David Ramirez
Summary: This study assessed the circulation of SARS-CoV-2 variants among vaccinated military personnel in Bogota, Colombia. The Mu lineage (B.1.621 and B.1.621.1) was found to be the most frequent infecting lineage in vaccinated individuals, possibly due to specific mutations conferring it with vaccine-induced immune escape ability. The findings highlight the importance of genomic tracking and epidemiological surveillance in studying emerging variants and their impact on global vaccination efforts.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Medicine, General & Internal
Luz H. Patino, Sergio Castaneda, Marina Munoz, Nathalia Ballesteros, Angie L. Ramirez, Nicolas Luna, Enzo Guerrero-Araya, Julie Perez, Camilo A. Correa-Cardenas, Maria Clara Duque, Claudia Mendez, Carolina Oliveros, Maryia V. Shaban, Alberto E. Paniz-Mondolfi, Juan David Ramirez
Summary: This study evaluates the dynamics of SARS-CoV-2 transmission in Cali, Colombia from April to July 2021, and finds clear differences in transmission during the period of protests compared to before and after. Genomic analysis identifies multiple SARS-CoV-2 lineages, with the Mu variant dominating during the study period. The results emphasize the importance of biosecurity strategies.
FRONTIERS IN MEDICINE
(2022)
Article
Immunology
Manuel Medina, Sara Zuluaga, Maria Fernanda Martinez, Juan Carlos Bermudez, Carolina Hernandez, Virgilio Beltran, Natalia Velasquez-Ortiz, Marina Munoz, Juan David Ramirez, Omar Triana, Omar Cantillo-Barraza
Summary: The study evaluated the long-term success of a Chagas disease vector control campaign in the Tenza Valley region of Boyaca, Colombia. The findings suggest that Triatoma venosa has ecological and epidemiological characteristics to maintain the transmission of T. cruzi. This species has reinfested intervened households and plays an active role in domestic and peridomestic transmission, highlighting its epidemiological relevance for vector control strategies. The study also emphasizes the importance of conducting human serological studies for understanding the risks they face.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Luz Helena Patino, Marina Munoz, Angie Lorena Ramirez, Norida Velez, Patricia Escandon, Claudia-Marcela Parra-Giraldo, Juan David Ramirez
Summary: By sequencing and analyzing the genomic architecture of 29 Colombian C. neoformans isolates, it was found that the majority belonged to the VNI molecular type. The study also revealed some SNP differences among these strains, but a low number of gene copy number variations and no changes in karyotype. These findings suggest that Colombian C. neoformans isolates may not require significant structural changes for host adaptation.
Article
Microbiology
Sergio Castaneda, Marina Munoz, Peter J. Hotez, Maria Elena Bottazzi, Alberto E. Paniz-Mondolfi, Kathryn M. Jones, Rojelio Mejia, Cristina Poveda, Juan David Ramirez
Summary: Chagas disease is caused by Trypanosoma cruzi and has a profound impact on the gastrointestinal tract. Alterations in the gut microbiome caused by the parasite may play a crucial role in host-parasite interactions and immune responses. Understanding this interaction could provide valuable insights into the pathophysiology of the disease and the development of new treatments.
MICROBIOLOGY SPECTRUM
(2023)
Article
Immunology
Sergio Castaneda, Gineth Ariza, Andres Rincon-Riveros, Marina Munoz, Juan David Ramirez
Summary: Feeding dogs with a BARF-type diet or a commercial diet can lead to changes in the composition and diversity of their gut microbiota. Dogs fed with a BARF diet have higher microbial diversity, while dogs fed with a commercial diet show enrichment of bacteria associated with carbohydrate metabolism.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2023)
Article
Immunology
Maria A. Badillo-viloria, Ignacio Garcia-Bocanegra, Rodrigo J. de Lavalle-Galvis, Remigio Martinez, Steffania de la Rosa-Jaramillo, Adriana Castillo-Castaneda, Juan D. Ramirez, David Cano-terriza
Summary: A cross-sectional study was conducted in the metropolitan area of the Colombian Caribbean to determine the prevalence of Dirofilaria immitis infection in pet dogs. The study found a relatively high frequency of infection, with exercise intolerance and thrombocytopenia being the main associated factors. The results emphasize the importance of using multiple diagnostic methods for accurate detection of D. immitis.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2023)
Article
Immunology
Giovanny Herrera, Laura Vega, Anny Camargo, Manuel Alfonso Patarroyo, Juan David Ramirez, Marina Munoz
Summary: This study found that the coexistence of Clostridium perfringens and Clostridium difficile can lead to minor differences in the composition and diversity of gut bacterial communities, particularly in patients with hospital-acquired diarrhea. These alterations suggest a need for a comprehensive understanding of gut microbiota.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Hallie Cohn, Nathaniel Bloom, Gianna Y. Cai, Jordan J. Clark, Alison Tarke, Maria C. Bermudez-Gonzalez, Deena R. Altman, Luz Amarilis Lugo, Francisco Pereira Lobo, Susanna Marquez, Jin-Qiu Chen, Wenlin Ren, Lili Qin, Jennifer L. Yates, Danielle T. Hunt, William T. Lee, Shane Crotty, Florian Krammer, Alba Grifoni, Alessandro Sette, Viviana Simon, Camila H. Coelho
Summary: This study compares human immune responses to JYNNEOS vaccination and monkeypox virus infection. The results show that infection with monkeypox virus elicits robust B-cell and T-cell responses, while JYNNEOS vaccination mainly induces T-cell responses.
LANCET INFECTIOUS DISEASES
(2023)
Article
Veterinary Sciences
Jeiczon Jaimes-Duenez, Adriana Castillo-Castaneda, Angela Jimenez-Leano, Jonny E. Duque, Omar Cantillo-Barraza, Diana Isabel Caceres-Rivera, Yurany Granada, Omar Triana-Chavez, Juan David Ramirez
Summary: This study investigated the eco-epidemiological factors associated with Leishmania spp. infection in dogs in a high-risk region for visceral leishmaniasis in eastern Colombia. The findings showed a high prevalence of infection in canine shelters and a diverse population of sand flies, but no potential vectors carrying Leishmania spp. The circulation of L. infantum in dogs suggests a latent risk of zoonotic transmission of the disease in this area.
PREVENTIVE VETERINARY MEDICINE
(2023)
Article
Multidisciplinary Sciences
Nathalia Ballesteros, Luisa Paez, Nicolas Luna, Ariana Reina, Vanessa Urrea, Catalina Sanchez, Angie Ramirez, Juan David Ramirez, Marina Munoz
Summary: Wetlands are important ecosystems due to their biodiversity, ecological functions, and ecosystem services. In Bogota, Colombia, there are 31,702 wetlands, 13 of which are in the capital. This study evaluated the status of seven Bogota wetlands with varying levels of anthropogenic impacts and found signs of contamination and potential pathogenic risks. The findings highlight the need for continuous monitoring of these water bodies to protect their ecological importance and prevent the spread of pathogens to humans and animals.
SCIENTIFIC REPORTS
(2023)
Article
Medical Laboratory Technology
Juan David Ramirez, Liyong Cao, Adriana C. Castillo-Castaneda, Luz Helena Patino, Martha S. Ayala, Carlos Cordon-Cardo, Emilia Mia Sordillo, Alberto Paniz-Mondolfi
Summary: This study evaluated the sensitivity of a molecular diagnostic method for leishmaniasis, which showed high sensitivity and specificity in clinical samples and the ability to estimate parasite burdens. This method has the potential to serve as a powerful tool for diagnosing and monitoring leishmaniasis.
PRACTICAL LABORATORY MEDICINE
(2023)
Article
Ecology
Lissa Cruz-Saavedra, Vivian Alejandra Arevalo, Diego Garcia-Corredor, Paula Andrea Jimenez, Laura Vega, Martin Pulido-Medellin, Melissa Ortiz-Pineda, Juan David Ramirez
Summary: This study investigated the prevalence of intestinal parasites in Colombian wild animals and found that Cryptosporidium, Giardia, and Blastocystis were the most commonly found parasites, with co-infections also observed.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-PARASITES AND WILDLIFE
(2023)
Article
Immunology
Hernan Dario Vergara, Carlos H. Gomez, Alvaro A. Faccini-Martinez, Ana Catalina Herrera, Maria Jose Lopez, Camila Camacho, Lilian Munoz, Lissa Cruz-Saavedra, Carolina Hernandez, Juan David Ramirez
Summary: This report describes an acute Chagas disease outbreak among soldiers in Colombia. Confirmation of Trypanosoma cruzi infection was done through parasitology, serology, and molecular methods. Treatment with benznidazole resulted in favorable outcomes for hospitalized soldiers. Patrol personnel in rural areas of Colombia may face an increased risk for Chagas disease.
EMERGING INFECTIOUS DISEASES
(2023)