DEG 15, an update of the Database of Essential Genes that includes built-in analysis tools

Genome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth

(2019) Yu Wang et al.   FASEB JOURNAL

Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies

(2019) Barbara Mair et al.   Cell Reports

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

(2019) Alyson R. Warr et al.   PLoS Pathogens

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

DoriC 10.0: an updated database of replication origins in prokaryotic genomes including chromosomes and plasmids

(2018) Hao Luo et al.   NUCLEIC ACIDS RESEARCH

The essential genome of the crenarchaeal model Sulfolobus islandicus

(2018) Changyi Zhang et al.   Nature Communications

Genome-wide identification of genes essential for podocyte cytoskeletons based on single-cell RNA sequencing

(2017) Yuqiu Lu et al.   KIDNEY INTERNATIONAL

Human gene essentiality

(2017) István Bartha et al.   NATURE REVIEWS GENETICS

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation

(2016) Jason D. Arroyo et al.   Cell Metabolism

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium

(2015) M. Lluch-Senar et al.   Molecular Systems Biology

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Identification of essential alphaproteobacterial genes reveals operational variability in conserved developmental and cell cycle systems

(2014) Patrick D. Curtis et al.   MOLECULAR MICROBIOLOGY

Genome-Wide Identification of Acinetobacter baumannii Genes Necessary for Persistence in the Lung

(2014) N. Wang et al.   mBio

A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium

(2013) Lars Barquist et al.   NUCLEIC ACIDS RESEARCH

DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements: Table 1.

(2013) Hao Luo et al.   NUCLEIC ACIDS RESEARCH

Genome-scale analysis of gene function in the hydrogenotrophic methanogenic archaeon Methanococcus maripaludis

(2013) F. Sarmiento et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Approaches to querying bacterial genomes with transposon-insertion sequencing

(2013) Lars Barquist et al.   RNA Biology

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Control of Virulence by Small RNAs in Streptococcus pneumoniae

(2012) Beth Mann et al.   PLoS Pathogens

Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis

(2012) Yanjia J. Zhang et al.   PLoS Pathogens

Genome-Scale Identification of Resistance Functions in Pseudomonas aeruginosa Using Tn-seq

(2011) L. A. Gallagher et al.   mBio

Functionality of essential genes drives gene strand-bias in bacterial genomes

(2010) Yan Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

(2009) G. C. Langridge et al.   GENOME RESEARCH

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

(2009) Tim van Opijnen et al.   NATURE METHODS

Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung

(2009) J. D. Gawronski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes

(2008) R. Zhang et al.   NUCLEIC ACIDS RESEARCH