Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-10-20
DOI
10.1038/s41591-020-1073-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
- (2020) Xiaofan Guo et al. Nature Communications
- Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy
- (2019) Tuba N. Gide et al. CANCER CELL
- Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development
- (2019) Gonzalo Herradon et al. Frontiers in Pharmacology
- Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages
- (2019) Marco Orecchioni et al. Frontiers in Immunology
- A view on drug resistance in cancer
- (2019) Neil Vasan et al. NATURE
- Immune checkpoint inhibitors in melanoma in the metastatic, neoadjuvant, and adjuvant setting
- (2019) Hugo Herrscher et al. CURRENT OPINION IN ONCOLOGY
- Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
- (2019) David Liu et al. NATURE MEDICINE
- T Cell Dysfunction in Cancer
- (2018) Daniela S. Thommen et al. CANCER CELL
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- Cancer immunotherapy using checkpoint blockade
- (2018) Antoni Ribas et al. SCIENCE
- T cell–induced CSF1 promotes melanoma resistance to PD1 blockade
- (2018) Natalie J. Neubert et al. Science Translational Medicine
- Association between expression of random gene sets and survival is evident in multiple cancer types and may be explained by sub-classification
- (2018) Yishai Shimoni PLoS Computational Biology
- Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition
- (2018) Cristiana Perrotta et al. Frontiers in Immunology
- Targeting Macrophages in Cancer: From Bench to Bedside
- (2018) Ashleigh R. Poh et al. Frontiers in Oncology
- Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer
- (2018) Fatemeh Shabani et al. INFLAMMATION RESEARCH
- The Role of Midkine in Arteriogenesis, Involving Mechanosensing, Endothelial Cell Proliferation, and Vasodilation
- (2018) Ludwig Weckbach et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
- (2018) Peng Jiang et al. NATURE MEDICINE
- Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
- (2018) Spencer C. Wei et al. Cancer Discovery
- A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
- (2018) Livnat Jerby-Arnon et al. CELL
- Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
- (2018) Hanjie Li et al. CELL
- Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy
- (2018) Razvan Cristescu et al. SCIENCE
- IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
- (2017) Mark Ayers et al. JOURNAL OF CLINICAL INVESTIGATION
- From top to bottom: midkine and pleiotrophin as emerging players in immune regulation
- (2017) Noah Sorrelle et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
- (2017) David Olmeda et al. NATURE
- Tumour-associated macrophages as treatment targets in oncology
- (2017) Alberto Mantovani et al. Nature Reviews Clinical Oncology
- Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells
- (2017) Michel Enamorado et al. Nature Communications
- The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis
- (2017) Geou-Yarh Liou et al. Cell Reports
- Nextpresso: Next Generation Sequencing Expression Analysis Pipeline
- (2017) O. Graña et al. Current Bioinformatics
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations
- (2016) Katrina Meeth et al. Pigment Cell & Melanoma Research
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade
- (2016) P.-L. Chen et al. Cancer Discovery
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
- (2015) E. M. Van Allen et al. SCIENCE
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via 2 integrins (CD11/CD18)
- (2014) L. T. Weckbach et al. BLOOD
- Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases
- (2014) D R Jones BRITISH JOURNAL OF PHARMACOLOGY
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The clinicopathological and gene expression patterns associated with ulceration of primary melanoma
- (2014) Rosalyn Jewell et al. Pigment Cell & Melanoma Research
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Innate and adaptive immune cells in the tumor microenvironment
- (2013) Thomas F Gajewski et al. NATURE IMMUNOLOGY
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Midkine upregulates MICA/B expression in human gastric cancer cells and decreases natural killer cell cytotoxicity
- (2012) Shuli Zhao et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator
- (2012) RUEDIGER LIERSCH et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Autocrine IFN- Promotes Naive CD8 T Cell Differentiation and Synergizes with IFN- To Stimulate Strong Function
- (2012) J. M. Curtsinger et al. JOURNAL OF IMMUNOLOGY
- Midkine in the pathology of cancer, neural disease, and inflammation
- (2012) Kazuma Sakamoto et al. PATHOLOGY INTERNATIONAL
- Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression
- (2011) Eline Dejonckheere et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Midkine in Inflammation
- (2011) Ludwig T. Weckbach et al. TheScientificWorldJOURNAL
- ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments
- (2010) Alexander Lachmann et al. BIOINFORMATICS
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Innate immune responses of primary murine macrophage-lineage cells and RAW 264.7 cells to ligands of Toll-like receptors 2, 3, and 4
- (2009) Londa J. Berghaus et al. COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
- Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
- (2009) David Sancho et al. NATURE
- Predicting free energy changes using structural ensembles
- (2008) Alexander Benedix et al. NATURE METHODS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started