Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Muc5b Enhances Murine Honeycomb-like Cyst Formation

(2019) Jonathan S. Kurche et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

BAL Cell Gene Expression is Indicative of Outcome and Airway Basal Cell Involvement in IPF

(2018) Antje Prasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype

(2018) Chaoqun Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

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Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration

(2017) Ying Xi et al.   NATURE CELL BIOLOGY

Decoding of position in the developing neural tube from antiparallel morphogen gradients

(2017) Marcin Zagorski et al.   SCIENCE

CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis

(2017) Guiquan Jia et al.   THORAX

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

(2016) Hongmei Mou et al.   Cell Stem Cell

BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors

(2016) Tomomi Tadokoro et al.   DEVELOPMENT

Rare SOX2 + Airway Progenitor Cells Generate KRT5 + Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection

(2016) Samriddha Ray et al.   Stem Cell Reports

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Yingying Dong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration

(2015) Tien Peng et al.   NATURE

The suture provides a niche for mesenchymal stem cells of craniofacial bones

(2015) Hu Zhao et al.   NATURE CELL BIOLOGY

Targeting the Hedgehog–Glioma-Associated Oncogene Homolog Pathway Inhibits Bleomycin-Induced Lung Fibrosis in Mice

(2014) Elika Farrokhi Moshai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

(2014) Andrew E. Vaughan et al.   NATURE

Hedgehog Signaling in Neonatal and Adult Lung

(2013) Li Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Idiopathic Pulmonary Fibrosis Honeycomb Cyst Contains A Mucocilary Pseudostratified Epithelium

(2013) Max A. Seibold et al.   PLoS One

Role of Sonic Hedgehog in idiopathic pulmonary fibrosis

(2012) Alfredo Lozano Bolaños et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis

(2011) L. Plantier et al.   THORAX

Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis

(2010) Amber L. Degryse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gremlin-mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis

(2007) Marjukka Myllärniemi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE