Article
Materials Science, Multidisciplinary
Dineshkumar Loganathan, Chia-Ling Hsieh, Bo-Er Shi, Yueh-Hsun Lu, Chia-Yuan Chen
Summary: Magnetic microrobots were fabricated using a block-to-block approach and two distinct modes of motion were demonstrated with the help of an electromagnetic system. Theoretical and numerical investigations were conducted to understand the physics of microrobot locomotion and their potential applications in flow agitation and particle dispersion were discussed. This work highlights the feasibility and potential of microrobots in medical and biological applications.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Robotics
Levent Cetin, Abdulkareem Alasli, Nail Akcura, Aytac Kahveci, Fatih Cemal Can, Ozgur Tamer
Summary: This paper investigates a new electromagnetic actuation principle for microscale manipulation. By changing the distance between electromagnets, a controlled magnetic force can be generated in combination with a robotic manipulator, enabling precise manipulation in three-dimensional space at the microscale. Numerical analysis and experimental validation demonstrate the feasibility and performance of this principle.
Article
Chemistry, Analytical
Shunnosuke Kodera, Tomoki Watanabe, Yoshiyuki Yokoyama, Takeshi Hayakawa
Summary: We propose a microgripper actuated by soft thermoresponsive hydrogels for manipulating a single living cell. By controlling the temperature of the thermoresponsive gel, the gripper can be driven. The experimental results demonstrate that the gripper is capable of gripping a cell with a size of approximately 10 μm.
Article
Automation & Control Systems
Manh Cuong Hoang, Jayoung Kim, Jong-Oh Park, Chang-Sei Kim
Summary: This paper presents a novel magnetic field control method to enhance the performance in terms of accuracy and field strength of underdetermined electromagnetic actuation systems. By developing computational optimization programming, alternative solutions that satisfy constraints are found, and the effectiveness of single- and multi-objective optimization techniques is compared.
Article
Chemistry, Analytical
Hiep Xuan Cao, Daewon Jung, Han-Sol Lee, Gwangjun Go, Minghui Nan, Eunpyo Choi, Chang-Sei Kim, Jong-Oh Park, Byungjeon Kang
Summary: Ultrasonic manipulation technology shows great potential in the field of therapeutic applications, especially the traveling wave-based manipulation method which has advantages in vivo environments. This study presents a novel UT array that can generate active traveling waves with phase modulation, successfully manipulating a micromotor in water. The feasibility of the method was demonstrated through in vitro and ex vivo experiments using a UT array with 16 transducers at 1 MHz.
Article
Chemistry, Analytical
Yuanyuan Wu, Yaran Chang, Yunlong Shao, Guangsheng Guo, Zhihong Liu, Xiayan Wang
Summary: This study proposed a method for the controllable fabrication of small-size holding pipets and achieved the active capture, movement, and sampling of suspended single cells. Moreover, the extracted compounds were successfully detected using an electrochemical method.
ANALYTICAL CHEMISTRY
(2022)
Article
Automation & Control Systems
Zhengxin Yang, Lidong Yang, Moqiu Zhang, Neng Xia, Li Zhang
Summary: In this article, a wired magnetic microrobot (WMM) is introduced for interventional therapy in hard-to-reach vascular regions. The WMM provides high efficiency, reliability, and flexibility, and offers precise navigation through ultrasound imaging monitoring.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Article
Multidisciplinary Sciences
Max Sokolich, David Rivas, Yanda Yang, Markos Duey, Sambeeta Das
Summary: This document presents a compact, low-cost, versatile, and user-friendly device called ModMag, which is capable of controlling multiple electromagnetic setups. The device includes a 10-inch touchscreen and a graphical user interface for easy operation. It can also be controlled remotely and interfaced with other software.
Proceedings Paper
Automation & Control Systems
Wei Zhang, Bin Song, Xue Bai, Jingli Guo, Lin Feng, Fumihito Arai
Summary: This paper presents a portable acoustofluidic device for multifunctional cell manipulation and 3D reconstruction using acoustically oscillating bottom bubble array. Through multiple bubble-induced microvortices generated by an Arduino-based driving system, it achieves self-propelled transportation, controllable trapping, and 3D rotation of cells. The device demonstrates great potentials in bioengineering, biophysics, and biomedicine with efficient cell reconstruction and manipulation capabilities.
2021 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA 2021)
(2021)
Proceedings Paper
Engineering, Electrical & Electronic
Fanping Sui, Yuanyuan Huang, Ruiqi Guo, Liwei Lin
Summary: This study demonstrates micro swimming robots powered by a single-axis magnetic system can achieve controllable mobility and stability. These robots can be controlled to move at different speeds and directions by adjusting the magnetic field, and can perform underwater maneuvers and maintain attitude stability effectively.
2021 21ST INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS (TRANSDUCERS)
(2021)
Article
Humanities, Multidisciplinary
Marcin Marian Krawczyk
Summary: This article argues that visual representations of financial markets not only reveal important financial information, but also hide manipulation. Due to their interactive nature, these visual representations can be manipulated by financial agents, leading to increased uncertainty in the markets.
Article
Chemistry, Physical
Yang Shi, Li Liang, Yunfeng Zuo, Xiaoqiang Zhu, Yi Yang, Hongbao Xin, Baojun Li
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Ting Pan, Wen Fu, Hongbao Xin, Shengyong Geng, Zhibin Li, Haodong Cui, Yanli Zhang, Paul K. Chu, Wenhua Zhou, Xue-Feng Yu
ADVANCED FUNCTIONAL MATERIALS
(2020)
Review
Engineering, Electrical & Electronic
Yuchao Li, Hongbao Xin, Yao Zhang, Baojun Li
Summary: Optical manipulation and detection of nanoscale biospecimen using micro/nano optical fibers have advantages over traditional lens-based free-space techniques due to their compact structure, flexibility, high sensitivity, and sub-diffraction-limit confinement. This review covers recent advances in nanoscale manipulation and biological detection with optical fibers, including applications for biological exploration like nanoparticle delivery and detection, single-molecule trapping and sensing, and single-cell manipulation and analysis, aiming to highlight current trends and future directions in this field.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2021)
Review
Optics
Ting Pan, Dengyun Lu, Hongbao Xin, Baojun Li
Summary: Biophotonic probes designed with biological entities offer multifunctional light manipulation at target sites, providing better biocompatibility and reducing invasiveness, thus providing new possibilities for bio-detection and imaging.
LIGHT-SCIENCE & APPLICATIONS
(2021)
Article
Engineering, Biomedical
Ting Pan, Wenjing Song, Hongbao Xin, Haiyue Yu, He Wang, Dandan Ma, Xiaodong Cao, Yingjun Wang
Summary: Bone defects pose a major threat to human health and the demand for bone tissue regeneration is increasing worldwide. This study highlights the importance of finding a balance between the degradation behavior of scaffolds and the release profile of miRNA for successful bone repair. The findings provide valuable insights for designing bioactive scaffolds for tissue regeneration.
BIOACTIVE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Ting Pan, Yang Shi, Nan Zhao, Jianyun Xiong, Yuqing Xiao, Hongbao Xin, Baojun Li
Summary: This study introduces a noncontact delivery platform based on bio-micromotor tweezers that can achieve precise control over bio-cargos in bio-microenvironments with minimal invasiveness, flexible controllability, and full biocompatibility. This approach effectively reduces biological damages and enables targeted drug delivery into single cancer cells. Such bio-micromotor tweezers hold great potential for diverse biomedical applications including targeted drug/cell delivery, drug testing, accurate diagnosis, and precise therapy.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Xiaoting Zhao, Yang Shi, Ting Pan, Dengyun Lu, Jianyun Xiong, Baojun Li, Hongbao Xin
Summary: The TOT technique allows for in situ single-cell surgery and manipulation of intracellular organelles without interfering with neighboring cells, enabling targeted gene delivery and providing a new approach for understanding cellular processes at a subcellular level.
Article
Chemistry, Analytical
Li Liang, Xuejia Hu, Yang Shi, Shukun Zhao, Qinghao Hu, Minhui Liang, Ye Ai
Summary: This paper introduces a novel optofluidic method for fabricating tunable liquid microlens arrays (MLAs) and demonstrates their ability to achieve tunable focusing and high-quality imaging. The focal length of the MLAs can be adjusted by changing the refractive index of the liquid droplets, showing promising opportunities for various applications.
ANALYTICAL CHEMISTRY
(2022)
Article
Optics
Yang Shi, Danning Wang, Yuqing Xiao, Ting Pan, Dengyun Lu, Guoshuai Zhu, Jianyun Xiong, Baojun Li, Hongbao Xin
Summary: This paper presents an intelligent microswarm actuation method based on light-induced cold Marangoni flow (CMF), which can achieve collective drug delivery and targeted cell chemotherapy. This method has strong universality and high controllability, and also exhibits intelligent biomimetic behaviors.
LASER & PHOTONICS REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Jianyun Xiong, Yang Shi, Ting Pan, Dengyun Lu, Ziyi He, Danning Wang, Xing Li, Guoshuai Zhu, Baojun Li, Hongbao Xin
Summary: Researchers report a biocompatible opto-hydrodynamic diatombot (OHD) based on optical trapping navigated rotational diatom (Phaedactylum tricornutum Bohlin) for non-invasive trapping and removal of nano-biothreats during cell culturing. This rotational OHD combines opto-hydrodynamic effect and optical trapping to enable trapping of bio-targets down to sub-100 nm. The OHDs show remarkable antibacterial capability and facilitate targeted gene delivery, making them a promising platform for trapping and removal of nano-biothreats in bio-microenvironments.
Article
Optics
Xing Li, Yang Shi, Ting Pan, Dengyun Lu, Guoshuai Zhu, Jianyun Xiong, Danning Wang, Ziyi He, Jingping Huang, Hongbao Xin
Summary: A convenient opto-hydrodynamic strategy for 3D dynamic microswarm actuation based on the photothermal gradient-induced Marangoni effect is proposed. Such microswarm petals are controllably reconfigurable, deformable, and capable of performing stable migration. Importantly, this opto-hydrodynamic strategy is applicable for the formation of artificial 3D-dynamic bio-microswarms using different biological cells, which further facilitate the regulation of biological processes such as bacteria growth/division.
LASER & PHOTONICS REVIEWS
(2023)
Article
Optics
Dengyun Lu, Guoshuai Zhu, Xing Li, Jianyun Xiong, Danning Wang, Yang Shi, Ting Pan, Baojun Li, Luke K. P. Lee, Hongbao Xin
Summary: Nanoplasmonic antennas allow label-free monitoring of bacterial enzyme release through outer membrane vesicles. Real-time monitoring reveals oscillatory behavior of enzyme release from individual bacteria and the impact of coupled oscillation from neighboring bacteria. Understanding the role of outer membrane vesicles as carriers of signaling enzymes provides insights into intercellular communication, pathogenesis, and biofilm formation.
Article
Biochemical Research Methods
Qinghao Hu, Xuejia Hu, Yang Shi, Li Liang, Jiaomeng Zhu, Shukun Zhao, Yifan Wang, Zezheng Wu, Fubing Wang, Fuling Zhou, Yi Yang
Summary: Highly heterogeneous structures are important for tissue functions, but controlling their assembly is a challenge. This research presents an on-demand bubble-assisted acoustic method for cell patterning to achieve precise heterogeneous structures. The method combines acoustic radiation forces and microstreaming around oscillating bubble arrays to achieve active cell patterning. The technique shows promise for tissue construction and has been successful in constructing a liver lobule model.
