Review
Biochemistry & Molecular Biology
Chen Yu, Bing Zhao, Yan Li, Hengchang Zang, Lian Li
Summary: This review discusses the current research status of osteoarthritis (OA), the importance of early diagnosis, the potential application of vibrational spectroscopy in OA diagnosis, comparison of various diagnostic methods, and the promising role of vibrational spectroscopy as a tool for early OA diagnosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Instruments & Instrumentation
Nicole M. Ralbovsky, Igor K. Lednev
Summary: Type II diabetes mellitus is a metabolic disorder with high prevalence and mortality rates worldwide, leading to various dangerous diseases. Current methods for diabetes detection have limitations in terms of fluctuation and accuracy, highlighting the need for more effective diagnostic approaches.
APPLIED SPECTROSCOPY
(2021)
Review
Chemistry, Analytical
Shuyan Zhang, Yi Qi, Sonia Peng Hwee Tan, Renzhe Bi, Malini Olivo
Summary: Molecular vibrations are essential in physical chemistry and biochemistry, and Raman and infrared spectroscopy are the primary techniques used for vibrational spectroscopy. These techniques provide distinct molecular fingerprints that can be used to identify chemical bonds, functional groups, and molecular structures. This review article explores recent advancements in using Raman and infrared spectroscopy for molecular fingerprint detection, focusing on identifying specific biomolecules and understanding the chemical composition of biological samples for cancer diagnosis. The article also discusses the working principles and instrumentation of each technique, highlighting the analytical versatility of vibrational spectroscopy.
Review
Oncology
Priyanshu Kumar Shrivastava, Ansul Kumar, Yogendra Aggarwal, Amit Kumar, Anushka Agrawal, Arpita Rai
Summary: Vibrational spectroscopy techniques such as Raman spectroscopy (RS) and Fourier-transform infrared (FTIR) spectroscopy show great potential in the early diagnosis of oral malignant and pre-malignant conditions, with high sensitivity and specificity.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
(2023)
Article
Chemistry, Analytical
Warda Boutegrabet, Dominique Guenot, Olivier Bouche, Camille Boulagnon-Rombi, Aude Marchal Bressenot, Olivier Piot, Cyril Gobinet
Summary: A new automatic and multivariate methodology utilizing EMSC regression coefficients, validity indices, and KMeans clustering was proposed to separate paraffin and tissue pixels in infrared spectral images. Validation on simulated and real images showed high effectiveness of the method.
ANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
A. Falamas, C. I. Faur, S. Ciupe, M. Chirila, H. Rotaru, M. Hedesiu, S. Cinta Pinzaru
Summary: This study tested a saliva samples preparation method for oral and oropharyngeal cancer diagnosis using micro-Raman and FT-IR spectroscopic techniques. Biomarker bands for cancer classification were identified, with a significant vibrational band at 2064 cm(-1) observed in both datasets. The oral and oropharyngeal cancer could be differentiated with 90% accuracy using micro-Raman data and 82% accuracy using FT-IR data.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Health Care Sciences & Services
Charlotte Delrue, Sander De Bruyne, Marijn M. M. Speeckaert
Summary: Infrared (IR) spectroscopy is a noninvasive and rapid analytical technique that provides information on the chemical composition, structure, and conformation of biomolecules in saliva. It has been widely used to analyze salivary biomolecules due to its label-free advantages. Saliva contains a complex mixture of biomolecules that can serve as potential biomarkers for various diseases, and IR spectroscopy has shown great promise in their diagnosis and monitoring. Recent advancements in IR spectroscopy, such as FTIR and ATR spectroscopy, have further improved its utility in salivary analysis.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Engineering, Environmental
Jieun Lee, Kyu-Jung Chae
Summary: Microplastics pose risks to ecosystems and human health, yet a systematic protocol for qualitative and quantitative analysis is still lacking in environmental analytical chemistry. These microplastics are spread through the food web to living organisms, and have even been detected in bottled water. Establishing a systematic protocol for microplastic identification is crucial to ensure accuracy, reliability, and reproducibility in determining their eco-toxicity and removal by biodegradation.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Chemistry, Analytical
Maria Chiara Sportelli, Christine Kranz, Boris Mizaikoff, Nicola Ciof
Summary: Biofilms are a major cause of health and environmental issues, with bacteria in biofilms showing greater resistance to biocides. Spectroscopic techniques play a crucial role in understanding biofilm formation. This review discusses recent progress and advantages/disadvantages of spectroscopic approaches for studying biofilms.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Analytical
Arya Suresh Babu, Anjali Tomar, Shweta Sharma
Summary: This study explores the existing trends in examining the sequence of ink strokes using vibrational spectroscopic techniques (infrared and Raman spectroscopy) and proposes future research directions in this field. The findings suggest that factors like paper type and time gap between strokes do not affect the determination of stroke sequence. The use of multiple analytical techniques in combination with vibrational spectroscopic techniques can provide reliable results.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Review
Instruments & Instrumentation
Mike Hardy, Liam Kelleher, Paulo de Carvalho Gomes, Emma Buchan, Hin On Martin Chu, Pola Goldberg Oppenheimer
Summary: This review summarizes the methods and applications of Raman spectroscopy combined with saliva, highlighting the need for standardization and further validation studies, while also recognizing the tremendous potential in improving speed, diagnostic accuracy, and portable device applications.
APPLIED SPECTROSCOPY REVIEWS
(2022)
Review
Chemistry, Multidisciplinary
Edward Ditler, Sandra Luber
Summary: Vibrational spectroscopy is an important experimental technique for characterizing molecules and materials, but the interpretation of experimental results can be challenging. Computational studies using molecular dynamics simulations provide a valuable tool for understanding and predicting experimental results. This review article summarizes the field of vibrational spectroscopy using first-principles molecular dynamics and highlights recent advances in simulation techniques.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Katarina Jansakova, Klaudia Kyselicova, Daniela Ostatnikova, Gabriela Repiska
Summary: Saliva, as a potential alternative to other body fluids, offers a complex view on the current state of the individual with its sources of nucleic acid of both human and microbial origin, protein, and non-protein molecules. Using salivary markers may simplify ASD screening and potentially reveal the etiopathogenesis of ASD, with the advantage of easier recruitment of neurotypical counterparts for studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Bayden R. Wood, Kamila Kochan, Diana E. Bedolla, Natalia Salazar-Quiroz, Samantha L. Grimley, David Perez-Guaita, Matthew J. Baker, Jitraporn Vongsvivut, Mark J. Tobin, Keith R. Bambery, Dale Christensen, Shivani Pasricha, Anthony K. Eden, Aaron Mclean, Supti Roy, Jason A. Roberts, Julian Druce, Deborah A. Williamson, Julie McAuley, Mike Catton, Damian F. J. Purcell, Dale Godfrey, Philip Heraud
Summary: The study introduces a portable infrared spectrometer for rapid detection of COVID-19 markers in saliva, demonstrating high sensitivity and specificity through modeling of experimental data. The testing method is quick, cost-effective, and suitable for mass screening, minimizing risks to healthcare workers.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Biochemistry & Molecular Biology
Sergey K. Pirutin, Shunchao Jia, Alexander I. Yusipovich, Mikhail A. Shank, Evgeniia Yu. Parshina, Andrey B. Rubin
Summary: The review provides an overview of different types of infrared (IR) and Raman spectroscopy methods. It discusses the basic principles and concepts of vibration spectroscopy and microspectrophotometry, with a focus on IR spectroscopy, mid- and near-IR spectroscopy, IR microspectroscopy, Raman spectroscopy, resonance Raman spectroscopy, Surface-enhanced Raman spectroscopy, and Raman microscopy. Examples of the use of these methods in the study of biological samples for environmental monitoring are presented. The authors conclude that near-IR spectroscopy-based methods are the most convenient for environmental studies, and the importance of using IR and Raman spectroscopy in environmental monitoring will continue to grow.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Stephane Derruau, Cyril Gobinet, Adeline Mateu, Valerie Untereiner, Sandrine Lorimier, Olivier Piot
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2019)
Article
Oncology
Archana Vijaya Kumar, Stephane Brezillon, Valerie Untereiner, Ganesh Dhruvananda Sockalingum, Sampath Kumar Katakam, Hossam Taha Mohamed, Bjoern Kemper, Burkhard Greve, Benedikt Mohr, Sherif Abdelaziz Ibrahim, Francisco M. Goycoolea, Ludwig Kiesel, Mauro S. G. Pavao, Juliana M. Motta, Martin Goette
Article
Biochemistry & Molecular Biology
Hossam Taha Mohamed, Valerie Untereiner, Gianfelice Cinque, Sherif Abdelaziz Ibrahim, Martin Goette, Nguyet Que Nguyen, Romain Rivet, Ganesh D. Sockalingum, Stephane Brezillon
Article
Biochemical Research Methods
Stephane Derruau, Cyril Gobinet, Valerie Untereiner, Ganesh D. Sockalingum, Aude Nassif, Manuelle Viguier, Olivier Piot, Sandrine Lorimier
Summary: The study demonstrates the potential of using infrared spectroscopy on saliva to diagnose hidradenitis suppurativa with an accuracy of about 80%. Risk factors such as obesity and smoking do not appear to affect the accuracy of infrared diagnosis for HS. This research highlights the possibility of developing a personalized medical approach for managing HS patients using salivary liquid biopsy combined with vibrational spectroscopy.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Oncology
Maxime Delarue, Stephane Derruau, Paul Troyon, Fabien Bogard, Guillaume Polidori, Cedric Mauprivez
Summary: Peripheral ameloblastoma (PA) is a rare benign tumor in the gingiva, with a high recurrence rate if not surgically excised completely. Medical infrared thermography (MIT) can help optimize surgical margins and minimize the risk of recurrence, as demonstrated in this case of a 71-year-old man with no local recurrence after two years of follow-up.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Review
Medicine, General & Internal
Stephane Derruau, Jerome Bouchet, Ali Nassif, Alexandre Baudet, Kazutoyo Yasukawa, Sandrine Lorimier, Isabelle Precheur, Agnes Bloch-Zupan, Bernard Pellat, Helene Chardin, Sophie Jung
Summary: The outbreak of COVID-19, caused by SARS-CoV-2, has greatly impacted the dental care sector, putting dental professionals at high risk of infection. The French National College of Oral Biology Lecturers answered questions related to COVID-19, providing an update for dentists.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Charlie Colin-Pierre, Valerie Untereiner, Ganesh D. Sockalingum, Nicolas Berthelemy, Louis Danoux, Vincent Bardey, Solene Mine, Christine Jeanmaire, Laurent Ramont, Stephane Brezillon
Summary: This study utilized infrared spectral imaging (IRSI) to investigate the expression and distribution changes of glypicans in different hair follicle compartments during various phases of the hair growth cycle, providing a new perspective on hair shaft growth. The results demonstrate the capability of IRSI to simultaneously reveal the location of proteins, PGs, GAGs, and sulfated GAGs in hair follicles in a reagent- and label-free manner.
Article
Oncology
Pierre Nizet, Valerie Untereiner, Ganesh D. Sockalingum, Isabelle Proult, Christine Terryn, Albin Jeanne, Lise Nannan, Camille Boulagnon-Rombi, Christele Sellier, Romain Rivet, Laurent Ramont, Stephane Brezillon
Summary: Lumican inhibits the growth of ovarian cancer by altering collagen fibrilogenesis. Immunohistochemical analysis confirmed the impact of lumican on tumor growth through this mechanism.
Article
Medicine, General & Internal
Stephane Derruau, Fabien Bogard, Guillaume Exartier-Menard, Cedric Mauprivez, Guillaume Polidori
Summary: This study demonstrates the use of Medical Infrared Thermography (MIT) as a precise tool to locate inflammatory focus in two patients with facial cellulitis, enhancing patient management and optimizing hospitalization decisions.
Article
Infectious Diseases
Quentin Lucidarme, Delphine Lebrun, Veronique Vernet-Garnier, Joey Le Gall, Saidou Diallo, Cedric Mauprivez, Stephane Derruau
Summary: This is a case report of a 15-year-old girl diagnosed with primary chronic osteomyelitis of the jaw. The diagnosis was confirmed through clinical examination, histopathological examination, and imaging modalities. After 6 months of antibiotic therapy, the disease achieved complete remission, and no relapse was reported after a 2-year follow-up.
Article
Biochemistry & Molecular Biology
Charlie Colin-Pierre, Valerie Untereiner, Ganesh D. Sockalingum, Laurent Ramont, Stephane Brezillon
Summary: The expression of glypicans in different hair follicle (HF) compartments was investigated using infrared spectral imaging (IRSI) for the first time, showing the distribution changes of GPC4 and GPC6 in HFs during different phases of the hair growth cycle. Western blot assays confirmed these findings. IRSI demonstrated its ability to identify the location of proteins, proteoglycans, glycosaminoglycans, and sulfated glycosaminoglycans in HFs in a label-free manner.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Integrative & Complementary Medicine
Fabien D. Legrand, Guillaume Polidori, Fabien Beaumont, Bastien Bouchet, Agnes Morin, Stephane Derruau, Esteban Brenet
Summary: This study assessed the impact of whole-body cryotherapy (WBC) on smelling capacities of COVID-19 recovered patients. Results showed significant improvements in the high-dose WBC group at follow-up, with a large effect size. However, the low-dose WBC group had smaller improvements. This suggests that WBC may be beneficial for recovering patients' olfactory function.
JOURNAL OF INTEGRATIVE AND COMPLEMENTARY MEDICINE
(2022)
