Journal
MOLECULAR BIOLOGY REPORTS
Volume 47, Issue 8, Pages 6239-6246Publisher
SPRINGER
DOI: 10.1007/s11033-020-05613-1
Keywords
Dust mite; Allergen; Clinical significance
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Funding
- National Natural Science Foundation of China [31729002, U1801286, 81971514]
- Key Projects of Guangdong (China) Science and Technology Plan [2017b0226006]
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Dust mites are an important cause of allergic diseases worldwide. The traces of Dermatophagoides farinae andDermatophagoides pteronyssinuscan be found all over the world, while Blomia tropicalis are more common allergenic mites in tropical areas. A variety of allergenic components in dust mites have been found, apart from the different positive rates of IgE reactions in dust mite allergic patients, their biological characteristics, effects on the innate immune system, and especially their distribution characteristics in patients are different. Studying the relationship between dust mite allergens and clinical significance will help for diagnosis of patients and formulation of corresponding Allergen Specific Immunotherapy.
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