Article
Endocrinology & Metabolism
Zeyu Liu, Qin Huang, Bi Deng, Minping Wei, Xianjing Feng, Fang Yu, Jie Feng, Yang Du, Jian Xia
Summary: CVAI is found to be associated with stroke risk in patients with MetS, with each 1 SD increase in CVAI associated with a 1.52-fold higher risk of stroke.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Sara Vizzuso, Alberico Del Torto, Dario Dilillo, Valeria Calcaterra, Elisabetta Di Profio, Alessandro Leone, Luisa Gilardini, Simona Bertoli, Alberto Battezzati, Gian Vincenzo Zuccotti, Elvira Verduci
Summary: This study evaluated the relationship between VAI, daily energy intake, and MetS in obese children and adolescents. The results showed that VAI was associated with several physiological parameters, while energy intake was positively correlated with BMI z-score, but not with VAI.
Article
Medicine, General & Internal
Stefano Lazzer, Mattia D'Alleva, Miriam Isola, Maria De Martino, Diana Caroli, Adele Bondesan, Alice Marra, Alessandro Sartorio
Summary: Recent evidence suggests that simple and inexpensive anthropometric measurements can help identify obese women at higher risk for developing metabolic syndrome. This study compared the accuracy of different adiposity and body composition indexes in identifying metabolic syndrome in a group of 876 women. The results showed that VAI and CMI performed the best in predicting metabolic syndrome, and these indexes were also the most sensitive and specific. This study highlights the usefulness of VAI and CMI in clinical practice for detecting metabolic syndrome in obese women.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Binqi Li, Jie Wang, Xin Zhou, Yang Liu, Weiqing Wang, Zhengnan Gao, Xulei Tang, Li Yan, Qin Wan, Zuojie Luo, Guijun Qin, Lulu Chen, Guang Ning, Yiming Mu
Summary: This study investigated the relationship between Chinese visceral adiposity index (CVAI) and hypertension and prehypertension, and compared its discriminative power with other adiposity indices in the Chinese population. The findings showed that CVAI was significantly associated with hypertension and prehypertension, and had superior discriminative ability compared to other indices.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Mustafa Suat Bolat, Mustafa Latif Ozbek, Bekir Sahin, Merve Yilmaz, Fatih Kocamanoglu, Recep Buyukalpelli, Ahmet Tevfik Sunter, Ramazan Asci
Summary: The study showed that metabolic syndrome affects male sexual function, with participants having higher VAI scores experiencing poorer erectile function. However, other sexual functions remained similar. This highlights the importance of comprehensive metabolic and endocrinological evaluation for ED patients with metabolic syndrome.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Xueyu Chen, Fengxue Shi, Juan Xiao, Fengyan Huang, Fang Cheng, Lihua Wang, Yanli Ju, Yong Zhou, Hongying Jia
Summary: This study investigated the associations between abdominal obesity indices and non-alcoholic fatty liver disease (NAFLD). The study found that waist circumference, visceral obesity index (VAI), lipid accumulation (LAP), and Chinese VAI (CVAI) were associated with NAFLD. After adjusting for potential confounders, the moderate-rising and high-rising groups of CVAI had the highest risk of NAFLD. CVAI had the best diagnostic value for NAFLD.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Luigi Barrea, Giovanna Muscogiuri, Roberta Modica, Barbara Altieri, Gabriella Pugliese, Roberto Minotta, Antongiulio Faggiano, Annamaria Colao, Silvia Savastano
Summary: Obesity, particularly visceral obesity, and metabolic syndrome (MetS) are major risk factors for type 2 diabetes, cardiovascular diseases, and cancer. This study investigated the association of Fatty Liver Index (FLI) and Visceral Adiposity Index (VAI) as early predictors of MetS with gastroenteropancreatic neuroendocrine tumors (GEP-NETs), finding that MetS, NAFLD, and visceral adiposity dysfunction are correlated with the worsening of clinicopathological characteristics in GEP-NET.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
A. A. Lopez-Gonzalez, A. Martinez Jover, C. Silveira Martinez, P. Martinez Artal, S. Arroyo Bote, Barbara Altisench Jane, J. Ramirez-Manent
Summary: There is no clear definition for metabolic syndrome, a condition characterized by coexisting visceral obesity, elevated lipids and glucose, and hypertension. This study aimed to determine the most suitable anthropometric indicators for diagnosing metabolic syndrome. The research found that CUN-BAE and Deuremberg indices were the most useful, followed by VAI.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Min Tang, Xiao-Hui Wei, Han Cao, Qin Zhen, Fang Liu, Yu-Fan Wang, Neng-Guang Fan, Yong-De Peng
Summary: The study aimed to investigate the correlation between the Chinese visceral adiposity index (CVAI) and metabolic-associated fatty liver disease (MAFLD) in Chinese adults with type 2 diabetes mellitus (T2DM). The results showed that CVAI was positively correlated with MAFLD, suggesting that it could be used as a diagnostic indicator for MAFLD in clinical practice for T2DM patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Mengyi Liu, Chun Zhou, Zhuxian Zhang, Panpan He, Yuanyuan Zhang, Di Xie, Jing Nie, Min Liang, Yun Song, Chengzhang Liu, Lishun Liu, Yong Huo, Binyan Wang, Xiaobin Wang, Xiping Xu, Xianhui Qin
Summary: The study revealed a positive association between VAI levels and the risk of new-onset proteinuria in hypertensive patients, which was consistent across participants with various characteristics.
CLINICAL NUTRITION
(2021)
Article
Rheumatology
Eric Toussirot, Francois Aubin, Maxime Desmarets, Daniel Wendling, Benoit Auge, Jerome Gillard, Olivier Messica, Xavier Guillot, Caroline Laheurte, Elisabeth Monnet, Gilles Dumoulin
Summary: Visceral fat accumulation is more pronounced in patients with PsO compared to those with PsA. Visceral adiposity may be a greater concern in PsO patients relative to PsA.
Article
Respiratory System
Sunyue He, Jie Yang, Xiaoyong Li, Hongxia Gu, Qing Su, Li Qin
Summary: This study reveals a clear correlation between the Visceral Adiposity Index (VAI) and lung function impairment in the Chinese population. A 10% increase in VAI was associated with a decrease in lung function predicted values in both men and women, with women also showing a positive correlation between VAI and FVC and FEV1 impairment.
RESPIRATORY RESEARCH
(2021)
Article
Psychology, Multidisciplinary
Jun Lei, Yaoyue Luo, Yude Xie, Xiaoju Wang
Summary: This study examined the association between VAI and depression in the American population using NHANES data. The results showed that for every 1 unit increase in VAI, the clinical depression increased by 14%. Patients with high VAI scores had the highest risk of developing depression.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Health Care Sciences & Services
Patricia Lizett Rodriguez-Carrillo, Priscila Irene Aguirre-Tostado, Maciste H. Macias-Cervantes, Jorge Alejandro Alegria-Torres, Claudia Luevano-Contreras
Summary: The study proposed Mexican adiposity indices (MAIs) and biochemical-anthropometric indices (BAIs), that performed well in identifying CR and MetS in Mexican adults. The VFA cut-off value of 100.3 cm(2) was found to be effective in identifying CR in Mexican men.
Article
Medicine, General & Internal
Priyanka Sharma, Avir Sarkar, Harnam Kaur, Usha Gupta, Binay Kumar
Summary: The study found that women with PCOS have higher visceral adiposity index (VAI), which is positively correlated with the severity of the disease and ovarian morphology. VAI assessment may be predictive of a greater propensity for development of classical metabolic risk factors in PCOS women.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Peripheral Vascular Disease
Conor Judge, Martin J. O'Donnell, Graeme J. Hankey, Sumathy Rangarajan, Siu Lim Chin, Purnima Rao-Melacini, John Ferguson, Andrew Smyth, Denis Xavier, Liu Lisheng, Hongye Zhang, Patricio Lopez-Jaramillo, Albertino Damasceno, Peter Langhorne, Annika Rosengren, Antonio L. Dans, Ahmed Elsayed, Alvaro Avezum, Charles Mondo, Danuta Ryglewicz, Anna Czlonkowska, Nana Pogosova, Christian Weimar, Rafael Diaz, Khalid Yusoff, Afzalhussein Yusufali, Aytekin Oguz, Xingyu Wang, Fernando Lanas, Okechukwu S. Ogah, Adesola Ogunniyi, Helle K. Iversen, German Malaga, Zvonko Rumboldt, Shahram Oveisgharan, Fawaz Al Hussain, Salim Yusuf
Summary: This study showed that both high and low urinary sodium excretion were associated with increased risk of stroke, with high sodium intake being a stronger risk factor for intracerebral hemorrhage than ischemic stroke. Urinary potassium levels were inversely and linearly associated with stroke risk, especially for ischemic stroke. The combination of moderate sodium intake and high potassium intake was associated with the lowest risk of stroke.
AMERICAN JOURNAL OF HYPERTENSION
(2021)
Article
Geriatrics & Gerontology
Filiz Demirdag, Esma Nur Kolbasi, Go zde Balkaya Aykut, Kubra Yildiz Guler, Sadiye Murat, Gulistan Bahat Ozturk, Aytekin Oguz
Summary: The study investigated the prevalence of sarcopenia, obesity, and sarcopenic obesity in older adults, and the role of nutrition as a mediator in the association between these factors and frailty. The findings showed that sarcopenia and sarcopenic obesity were associated with frailty, while obesity itself did not have a direct impact on frailty. Nutritional status was found to be a mediator between age-related muscle loss and frailty.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Article
Cardiac & Cardiovascular Systems
Andrew Smyth, Martin O'Donnell, Graeme J. Hankey, Sumathy Rangarajan, Patricio Lopez-Jaramillo, Denis Xavier, Hongye Zhang, Michelle Canavan, Albertino Damasceno, Peter Langhorne, Alvaro Avezum, Nana Pogosova, Aytekin Oguz, Salim Yusuf
Summary: The INTERSTROKE study found that acute stroke is associated with anger or emotional upset and heavy physical exertion. Anger or emotional upset is associated with all stroke, ischemic stroke, and intracerebral hemorrhage, while heavy physical exertion is only associated with intracerebral hemorrhage.
EUROPEAN HEART JOURNAL
(2022)
Review
Integrative & Complementary Medicine
Berna Dincer, Demet Inangil, Gokhan Inangil, Nefise Bahcecik, Elif Yildirim Ayaz, Ali Arslanoglu, Mirac Vural Keskinler, Ayse Kabuk, Gamze Ozkan
Summary: This study conducted a systematic review and meta-analysis to determine the effect of acupressure on sleep quality in elderly people. The results showed that acupressure significantly improved sleep quality in elderly individuals, both when applied by professionals and when self-applied.
EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
(2022)
Article
Cardiac & Cardiovascular Systems
Darryl P. Leong, Sumathy Rangarajan, Annika Rosengren, Aytekin Oguz, Khalid F. Alhabib, Paul Poirier, Rafael Diaz, Antonio L. Dans, Romaina Iqbal, Afzalhussein M. Yusufali, Karen Yeates, Jephat Chifamba, Pamela Seron, Jose Lopez-Lopez, Ahmad Bahonar, Li Wei, Hu Bo, Liu Weida, Alvaro Avezum, Rajeev Gupta, Viswanathan Mohan, Herculina S. Kruger, P. V. M. Lakshmi, Rita Yusuf, Salim Yusuf
Summary: This study analyzed nearly 150,000 participants from different countries and found that the use or non-use of cardiovascular medications had different impacts on the risk of cardiovascular disease and death. Pharmacological interventions targeting hypertension, diabetes, and high thrombotic levels in individuals with elevated BMI may help reduce the burden of cardiovascular disease.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Clinical Neurology
Martin J. O'Donnell, Matthew McQueen, Allan Sniderman, Guillaume Pare, Xingyu Wang, Graeme J. Hankey, Sumathy Rangarajan, Siu Lim Chin, Purnima Rao-Melacini, John Ferguson, Denis Xavier, Liu Lisheng, Hongye Zhang, Prem Pais, Patricio Lopez-Jaramillo, Albertino Damasceno, Peter Langhorne, Annika Rosengren, Antonio L. Dans, Ahmed Elsayed, Alvaro Avezum, Charles Mondo, Conor Judge, Hans-Christoph Diener, Danuta Ryglewicz, Anna Czlonkowska, Nana Pogosova, Christian Weimar, Romana Iqbal, Rafael Diaz, Khalid Yusoff, Afzalhussein Yusufali, Aytekin Oguz, Ernesto Penaherrera, Fernando Lanas, Okechukwu S. Ogah, Adesola Ogunniyi, Helle K. Iversen, German Malaga, Zvonko Rumboldt, Shahram Oveisgharan, Fawaz Al Hussain, Yongchai Nilanont, Salim Yusuf
Summary: This study investigated the association of lipoproteins and apolipoproteins with stroke in a standardized incident case-control investigation across 32 countries. The results showed that the association between dyslipidemia and stroke varied depending on the etiological subtype of stroke. Increased apoB and LDL-C were associated with an increased risk of ischemic stroke, while being associated with a reduced risk of intracerebral hemorrhage (ICH). Higher HDL-C and apoA1 were associated with ischemic stroke and its subtypes, but HDL-C was associated with an increased risk of ICH and apoA1 was associated with a reduced risk. The ratio of apoB/A1 was the best predictor of ischemic stroke risk.
Review
Dermatology
Elif Yildirim Ayaz, Berna Dincer, Aytekin Oguz
Summary: This systematic review and meta-analysis examined the impact of foot care education on knowledge, self-efficacy, and behavior in patients with diabetes. The results showed that foot care education improved patients' knowledge and behavior, but did not significantly affect their self-efficacy. Long-term educational interventions are needed to meet the increasing healthcare needs of patients with diabetes.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2022)
Article
Cardiac & Cardiovascular Systems
Sidong Li, Scott A. Lear, Sumathy Rangarajan, Bo Hu, Lu Yin, Shrikant Bangdiwala, Khalid F. Alhabib, Annika Rosengren, Rajeev Gupta, Prem K. Mony, Andreas Wielgosz, Omar Rahman, M. Y. Mazapuspavina, Alvaro Avezum, Aytekin Oguz, Karen Yeates, Fernando Lanas, Antonio Dans, Marc Evans M. Abat, Afzalhussein Yusufali, Rafael Diaz, Patricio Lopez-Jaramillo, Lloyd Leach, P. V. M. Lakshmi, Alicja Basiak-Rasala, Romaina Iqbal, Roya Kelishadi, Jephat Chifamba, Rasha Khatib, Wei Li, Salim Yusuf
Summary: Sitting for long periods of time is associated with increased risks of cardiovascular disease and mortality, especially in low- and middle-income countries. Reducing sedentary time and increasing physical activity may be an important strategy to reduce the global burden of premature deaths and cardiovascular disease.
Article
Medicine, General & Internal
Marjan Walli-Attaei, Annika Rosengren, Sumathy Rangarajan, Yolandi Breet, Suraya Abdul-Razak, Wadeia Al Sharief, Khalid F. Alhabib, Alvaro Avezum, Jephat Chifamba, Rafael Diaz, Rajeev Gupta, Bo Hu, Romaina Iqbal, Rosnah Ismail, Roya Kelishadi, Rasha Khatib, Xinyue Lang, Sidong Li, Patricio Lopez-Jaramillo, Viswanathan Mohan, Aytekin Oguz, Lia M. Palileo-Villanueva, Katarzyna Poltyn-Zaradna, P. R. Sreelakshmi, Lakshmi V. M. Pinnaka, Pamela Seron, Koon Teo, Sejil T. Verghese, Andreas Wielgosz, Karen Yeates, Rita Yusuf, Sonia S. Anand, Salim Yusuf
Summary: There is a lack of data on the prevalence of risk factors and their associations with incident cardiovascular disease in women compared with men. This study aimed to investigate the risks and related factors of cardiovascular disease in women and men from low-income and middle-income countries over a 10-year follow-up period.
Article
Clinical Neurology
Andrew Smyth, Martin O'Donnell, Sumathy Rangarajan, Graeme J. Hankey, Shahram Oveisgharan, Michelle Canavan, Clodagh McDermott, Denis Xavier, Hongye Zhang, Albertino Damasceno, Alvaro Avezum, Nana Pogosova, Aytekin Oguz, Danuta Ryglewicz, Helle Klingenberg Iversen, Fernando Lanas, Annika Rosengren, Salim Yusuf, Peter Langhorne
Summary: This study examined the association between alcohol consumption and stroke in a large international population. It found that high and moderate alcohol intake increased the odds of stroke, while low intake was not associated with stroke. However, there were regional variations in the relationship.
Article
Gastroenterology & Hepatology
Neeraj Narula, Emily C. L. Wong, Cara Pray, John K. Marshall, Sumathy Rangarajan, Shofiqul Islam, Ahmad Bahonar, Khalid F. Alhabib, Anna Kontsevaya, Farnaza Ariffin, Homer U. Co, Wadeia Al Sharief, Andrzej Szuba, Andreas Wielgosz, Maria Luz Diaz, Rita Yusuf, Lanthe Kruger, Biju Soman, Yang Li, Chuangshi Wang, Lu Yin, Erkin Mirrakhimov, Fernando Lanas, Kairat Davletov, Annika Rosengren, Patricio Lopez-Jaramillo, Rasha Khatib, Aytekin Oguz, Romaina Iqbal, Karen Yeates, Alvaro Avezum, Walter Reinisch, Paul Moayyedi, Salim Yusuf
Summary: The study found that antibiotics, hormonal medications, oral contraceptives, and long-term nonsteroidal anti-inflammatory drug use were associated with an increased risk of incident IBD in participants. These results were consistent for both Crohn's disease and ulcerative colitis.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Urban Studies
Kwadwo Boakye, Marit Bovbjerg, John Schuna Jr, Adam Branscum, Nafiza Mat-Nasir, Ahmad Bahonar, Olga Barbarash, Rita Yusuf, Patricio Lopez-Jaramillo, Pamela Seron, Annika Rosengren, Karen Yeates, Jephat Chifamba, Khalid F. Alhabib, Kairat Davletov, Mirac Vural Keskinler, Maria Diaz, Lanthe Kruger, Yang Li, Liu Zhiguang, Lap Ah. Tse, Andreas Wielgosz, Koon Teo, Mirrakhimov Erkin, Sumathy Rangarajan, Scott Lear, Salim Yusuf, Perry Hystad
Summary: This study investigated the relationship between built environment characteristics and walking/cycling behaviors in 355 urban communities across 21 low-, middle-, and high-income countries. The findings showed that land-use mix diversity, land-use mix access, street connectivity, safety from traffic, safety from crime, and aesthetics were associated with higher odds of walking and cycling behaviors. These results can inform policymakers globally in implementing built environment designs that encourage walking and cycling.
Article
Medicine, General & Internal
Mirac Vural Keskinler, Berna Dincer, Ozge Telci Caklili, Aytekin Oguz
Summary: The objective of this study was to observe the changes in osmolarity levels among type 2 diabetic patients fasting during Ramadan. The results showed that there were no significant changes in serum osmolality levels during fasting, indicating no biochemical signs of dehydration in these patients.
JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
(2023)
Article
Public, Environmental & Occupational Health
Maria Khan, Mohammad Wasay, Martin James O'Donnell, Romaina Iqbal, Peter Langhorne, Annika Rosengren, Albertino Damasceno, Aytekin Oguz, Fernando Lanas, Nana Pogosova, Fawaz Alhussain, Shahram Oveisgharan, Anna Czlonkowska, Danuta Ryglewicz, Salim Yusuf
Summary: Cardiac causes, binge drinking, hypertension, increased waist-to-hip ratio, psychosocial stress, smoking, and certain lipid levels are important risk factors for ischemic stroke in individuals under 45 years of age. For intracerebral hemorrhage, only hypertension and binge drinking are significant risk factors in this age group. Hypertension is the most significant risk factor for stroke in all age groups and regions.
Article
Medicine, General & Internal
Aditya K. Khetan, Salim Yusuf, Patricio Lopez-Jaramillo, Andrzej Szuba, Andres Orlandini, Nafiza Mat-Nasir, Aytekin Oguz, Rajeev Gupta, Alvaro Avezum, Ismail Rosnah, Paul Poirier, Koon K. Teo, Andreas Wielgosz, Scott A. Lear, Lia M. Palileo-Villanueva, Pamela Seron, Jephat Chifamba, Sumathy Rangarajan, Maha Mushtaha, Deepa Mohan, Karen Yeates, Martin McKee, Prem K. Mony, Marjan Walli-Attaei, Hamda Khansaheb, Annika Rosengren, Khalid F. Alhabib, Iolanthe M. Kruger, Maria-Jose Paucar, Erkin Mirrakhimov, Batyrbek Assembekov, Darryl P. Leong
Summary: The COVID-19 pandemic has created financial impact on individuals worldwide, with high rates of job loss and inability to meet financial needs. Education level and wealth are associated with the degree of financial impact. Disparities exist in financial impact between high-income countries (HIC), upper-middle-income countries (UMIC), and lower-middle-income countries (LMIC), highlighting the importance of controlling the pandemic to reduce financial inequality and achieve sustainable development goals.
