Article
Biochemistry & Molecular Biology
Sungtae Lim, Sung-Sahn Lee, Juyong Oh, Dae-Hee Lee
Summary: This study aimed to understand the impact of obesity on operation time in patients with arthroscopic anterior cruciate ligament (ACL) reconstruction. Through analysis of 103 patients, it was found that weight and BMI were positively correlated with operation time, and patients weighing over 74.25 kg were more likely to experience delayed surgery.
Article
Medicine, General & Internal
Zhong Chen, Yuheng Li, Yichi Zhang, Zhengzheng Zhang, Jingsong Wang, Xinghao Deng, Chengxiao Liu, Na Chen, Chuan Jiang, Weiping Li, Bin Song
Summary: This study found that visual function defect, especially low visual fusion range, is a risk factor for knee anterior cruciate ligament (ACL) sports injury. Quick turn, sudden stop, and jump during sports activities are also major risk factors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Analytical
Mazhar Javed Awan, Mohd Shafry Mohd Rahim, Naomie Salim, Amjad Rehman, Begonya Garcia-Zapirain
Summary: This study applies deep learning to automatically segment ACL tears from MRI images. By using the U-Net architecture and semantic segmentation technique, high accuracy segmentation results have been achieved. The method shows promising potential in the field of medical image analysis.
Article
Orthopedics
A. M. Davis, R. Wong, K. Steinhart, L. Cruz, D. Cudmore, T. Dwyer, L. Li, P. Marks, R. McGlasson, N. Urquhart, J. A. Wilson, L. Nimmon, D. Ogilvie-Harris, J. Chahal
Summary: An intervention to support individuals with ACL injury to limit and manage knee OA requires content embedded within an easily accessible, multi-media delivery model with capacity for check-back with HCPs that is appealing to different age groups and personal preferences over the lifespan post injury. Delivery timing reflects a lifespan approach from time of injury through symptomatic knee OA management.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Article
Orthopedics
Heng Gong, Qingshan Li, Yu Len, Ke He, Wenbo Zhao, Yu Li, Guanjun Sun, Xu Peng, Yi Yin
Summary: This study aimed to clarify the clinical value of the posterior cruciate ligament index (PCLI) in anterior cruciate ligament (ACL) rupture, explore its relationship with the course of disease, and identify its influencing factors. The results showed that the PCLI decreased with time, especially in the chronic phase, and was not related to the depth of the lateral femoral notch sign or injuries of other structures in the knee joint. It can be used as a reliable indirect sign of ACL rupture.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Review
Orthopedics
Eoghan T. Hurley, Jordan W. Fried, Matthew T. Kingery, Eric J. Strauss, Michael J. Alaia
Summary: The current evidence supports the notion that concomitant ALL reconstruction alongside soft tissue graft ACL reconstruction can improve clinical outcomes by enhancing knee stability and reducing re-rupture rates.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)
Article
Orthopedics
Y. Rehman, A. M. Korsvold, A. Lerdal, A. Aamodt
Summary: This study compared patient-reported outcomes of three total knee arthroplasty (TKA) designs from one manufacturer. The results showed that patients reported similar levels of pain, function, satisfaction, and general health regardless of the prosthetic design they received. Patients who received the posterior-stabilized (PS) design had better range of motion.
BONE & JOINT JOURNAL
(2023)
Article
Medicine, General & Internal
Xiaofen LI, Si Nie, Min Lan
Summary: The study found that medial posterior tibial slope, lateral posterior tibial slope, notch width, and body mass index were independent risk factors associated with noncontact ACL tears.
MEDICINA DELLO SPORT
(2022)
Article
Orthopedics
Kyoung-Tak Kang, Yong-Gon Koh, Kyoung-Mi Park, Chong-Hyuk Choi, Min Jung, Hyunik Cho, Sung-Hwan Kim
Summary: This study investigated the association between the anterolateral ligament (ALL) and anterior cruciate ligament (ACL) under dynamic loading conditions using computer simulation. The results showed that ACL deficiency significantly increased the force exerted on the ALL, and vice versa. Additionally, deficiencies in ACL and ALL increased the contact forces on the tibiofemoral (TF) and patellofemoral (PF) joints.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Review
Sport Sciences
Nirav Maniar, Michael H. Cole, Adam L. Bryant, David A. Opar
Summary: This review investigated the relationship between muscle force and ACL loading, revealing that the quadriceps and gastrocnemius increase ACL load, while the hamstrings, soleus, and gluteus medius unload the ACL. Limited evidence was found for other muscle groups. Interventions aiming to reduce ACL injury risk should focus on the function of the hamstrings, soleus, and gluteus medius.
Article
Biochemistry & Molecular Biology
Laura Rizzi, Marco Turati, Elena Bresciani, Filippo Maria Anghilieri, Ramona Meanti, Laura Molteni, Massimiliano Piatti, Nicolo Zanchi, Silvia Coco, Francesco Buonanotte, Luca Rigamonti, Giovanni Zatti, Vittorio Locatelli, Robert J. J. Omeljaniuk, Marco Bigoni, Antonio Torsello
Summary: This study investigated the changes in microRNA expression profiles in knee synovial fluid of patients with osteoarthritis (OA) and anterior cruciate ligament (ACL) rupture. The results showed that specific microRNAs were expressed differently in OA and ACL tear samples. These findings may contribute to further research on the mechanisms and treatments of osteoarthritis and ACL rupture.
Article
Engineering, Biomedical
Huijuan Shi, Li Ding, Shuang Ren, Yanfang Jiang, Haocheng Zhang, Xiaoqing Hu, Hongshi Huang, Yingfang Ao
Summary: Biomechanical risk factors associated with ACL injury are still inconclusive. Bone bruises identified post-ACL injury on MRI may represent the impact footprint, indicating changes in knee kinematics during injury.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Orthopedics
Lukas Willinger, Kiron K. Athwal, Andy Williams, Andrew A. Amis
Summary: This study established an in vitro ACL injury model that replicated clinical ACL injury evidenced by bone bruise patterns. ACL injury caused larger increases in laxity than ACL transection, likely due to damage to adjacent tissues; these differences often persisted after ACL reconstruction.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Article
Medicine, General & Internal
Marc Dauty, Vincent Crenn, Bastien Louguet, Jerome Grondin, Pierre Menu, Alban Fouasson-Chailloux
Summary: This study identified age, body mass index, knee laxity, knee strength, and passive knee alignment as risk factors for non-contact ACL injuries. Among these factors, age, passive knee extension, and weak hamstring strength were associated with a higher risk, while passive knee valgus was specifically identified as a risk factor for women. These findings suggest that hamstring strengthening exercises could be beneficial in preventing ACL injuries in young male athletes or individuals with knee laxity.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cell Biology
Adrian Guerra-Gonzalez, Carmen da Casa, Inigo Crespo, David Pescador, Lorena Benito-Garzon, Juan F. Blanco
Summary: The study found that ACL degeneration and innervation deficit may play a role in the onset of primary knee osteoarthritis, but the lack of a defining relationship among the different parameters assessed justifies further research in larger populations.
HISTOLOGY AND HISTOPATHOLOGY
(2022)
Article
Orthopedics
Troy Blackburn, Darin A. Padua, Brian Pietrosimone, Todd A. Schwartz, Jeffrey T. Spang, Jonathan S. Goodwin, Derek R. Dewig, Chris D. Johnston
Summary: This study evaluated the effects of whole-body vibration (WBV) and local muscle vibration (LMV) on gait biomechanics in individuals with ACLR. LMV decreased the vGRF loading rate significantly, while WBV increased the peak internal knee extension moment. These findings suggest that vibration has the potential to mitigate aberrant gait biomechanics and reduce the risk of posttraumatic knee osteoarthritis following ACLR.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2021)
Article
Sport Sciences
Hope C. Davis-Wilson, Louise M. Thoma, Lara Longobardi, Jason R. Franz, J. Troy Blackburn, A. C. Hackney, Brian Pietrosimone
Summary: In individuals who have undergone ACL reconstruction, those with symptoms spend more time in moderate-to-vigorous physical activity, which is associated with higher quality of life. However, there is no association between knee function and physical activity in individuals without symptoms post-ACLR.
JOURNAL OF ATHLETIC TRAINING
(2022)
Article
Neurosciences
Cortney Armitano-Lago, Brian Pietrosimone, Alyssa Evans-Pickett, Hope Davis-Wilson, Jason R. Franz, Troy Blackburn, Adam W. Kiefer
Summary: This study investigated the impact of altering lower extremity loading on inter- and intralimb joint coordination during gait, finding that low loading decreased coordination stability while high loading resulted in a more tightly coupled coordination pattern. With careful movement control, biofeedback can target mechanisms leading to long-term deleterious joint adaptations.
JOURNAL OF MOTOR BEHAVIOR
(2022)
Article
Sport Sciences
Alyssa Evans-Pickett, Hope C. Davis-Wilson, Christopher D. Johnston, J. Troy Blackburn, Anthony C. Hackney, Brian Pietrosimone
Summary: Braced walking may improve sagittal-plane gait biomechanics and cartilage outcomes in individuals after ACL reconstruction.
JOURNAL OF ATHLETIC TRAINING
(2023)
Article
Orthopedics
Hope C. Davis-Wilson, Louise M. Thoma, Christopher D. Johnston, Emma Young, Alyssa Evans-Pickett, Jeffrey T. Spang, J. Troy Blackburn, Anthony C. Hackney, Brian Pietrosimone
Summary: The study found that in individuals undergoing ACLR, fewer daily steps and less time spent walking at speeds exceeding 100 steps/min were significantly associated with a higher increase in COMP after walking. This suggests that ACLR patients engaging in less daily walking may experience greater cartilage degradation or turnover in response to walking.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Sport Sciences
Caroline Lisee, Hope C. Davis-Wilson, Alyssa Evans-Pickett, W. Zachary Horton, J. Troy Blackburn, Jason R. Franz, Louise M. Thoma, Jeffrey T. Spang, Brian G. Pietrosimone
Summary: Individuals who take the fewest daily steps after ACL reconstruction (ACLR) also exhibit reduced vertical ground reaction force (vGRF) and a stiffer knee strategy throughout stance.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Engineering, Biomedical
Brecca M. M. Gaffney, Nicholas W. Vandenberg, Hope C. Davis-Wilson, Cory L. Christiansen, Galen F. Roda, Gary Schneider, Tony Johnson, Jason W. Stoneback
Summary: Osseointegrated prostheses can improve movement patterns and muscle forces in patients with transfemoral amputation, reducing the risk of overuse injuries and improving functional outcomes.
CLINICAL BIOMECHANICS
(2022)
Article
Orthopedics
Paul W. Kline, Hope C. Davis-Wilson, Noel F. So, Thomas T. Fields, Cory L. Christiansen
Summary: The feasibility and efficacy of an eight-session error-augmentation gait training protocol were evaluated in people with non-traumatic transtibial amputation. The results showed that the protocol was well-accepted and safe, and it effectively improved step length asymmetry.
PROSTHETICS AND ORTHOTICS INTERNATIONAL
(2022)
Article
Neurosciences
Brecca M. M. Gaffney, Hope C. Davis-Wilson, Cory L. Christiansen, Mohamad E. Awad, Guy Lev, James Tracy, Jason W. Stoneback
Summary: Compared to socket prostheses, osseointegrated prostheses improve balance for individuals with unilateral transfemoral amputation by reducing postural sway, gait variability, and increasing balance confidence.
Article
Engineering, Biomedical
Hope C. Davis-Wilson, Cory L. Christiansen, Brecca M. M. Gaffney, Guy Lev, Eseosa Enabulele, Christopher Hoyt, Jason W. Stoneback
Summary: The study evaluated the longitudinal changes in joint kinetics one year after osseointegration in patients with transfemoral amputation. It found improved gait symmetry in individuals with transfemoral amputation one year following osseointegration.
CLINICAL BIOMECHANICS
(2023)
Article
Physiology
Caroline Lisee, Alyssa Evans-Pickett, Hope Davis-Wilson, Amanda E. Munsch, Lara Longobardi, Todd A. Schwartz, David Lalush, Jason R. Franz, Brian Pietrosimone
Summary: This study aimed to determine the associations between immediate and delayed response of serum cartilage oligomeric matrix protein (sCOMP) to loading and femoral cartilage interlimb T1 rho relaxation times following ACL reconstruction. The results indicated that greater delayed sCOMP response to loading was associated with worse lateral femoral cartilage composition.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Computer Science, Information Systems
Dorota S. Temple, Meghan Hegarty-Craver, Pooja Gaur, Matthew D. Boyce, Jonathan R. Holt, Edward A. Preble, Randall P. Eckhoff, Hope Davis-Wilson, Howard J. Walls, David E. Dausch, Matthew A. Blackston
Summary: This paper presents a novel modular architecture for collecting and processing high-resolution signals from wearable sensors, enabling continuous and near real-time health monitoring. The system operates independently by directly obtaining minimally processed data from the smartwatch and further processing and analyzing the data stream. It has the potential to expand the use of smartwatches for continuous and near real-time monitoring of health and well-being.
APPLIED SYSTEM INNOVATION
(2023)
Article
Sport Sciences
Caroline Michele Lisee, Elizabeth Bjornsen, W. Zachary Horton, Hope Davis-Wilson, J. Troy Blackburn, Matthew B. Fisher, Brian Pietrosimone
Summary: Adolescents and adults demonstrate different gait patterns post-ACLR, suggesting that age may play a role in altered gait biomechanics.
JOURNAL OF ATHLETIC TRAINING
(2022)
Article
Engineering, Biomedical
Amanda E. Munsch, Alyssa Evans-Pickett, Hope Davis-Wilson, Brian Pietrosimone, Jason R. Franz
Summary: Insufficient quadriceps force production and altered knee joint biomechanics after ACL reconstruction may increase the risk of osteoarthritis. This study quantified the changes in quadriceps muscle length and its correlation with gait biomechanics during weight acceptance in individuals with ACL reconstruction. The results suggest that examining quadriceps muscle dynamics may help understand the underlying mechanisms related to osteoarthritis.
JOURNAL OF APPLIED BIOMECHANICS
(2022)