The Role of Inflammation in the Pathogenesis of Preeclampsia

Metabolic Syndrome mediates pro-inflammatory responses of inflammatory cells in preeclampsia

(2019) Gisoo Jabalie et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Association of pro- and anti-inflammatory cytokines in preeclampsia

(2019) Ruby Aggarwal et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Decidua Basalis Mesenchymal Stem Cells Favor Inflammatory M1 Macrophage Differentiation In Vitro

(2019) Mohamed H. Abumaree et al.   Cells

Trophoblast-derived hyaluronan promotes the regulatory phenotype of decidual macrophages

(2019) Songcun Wang et al.   REPRODUCTION

Characterization of fetal monocytes in preeclampsia and fetal growth restriction

(2019) Thushari I. Alahakoon et al.   JOURNAL OF PERINATAL MEDICINE

Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction

(2019) Olivia Nonn et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Assessment efficacy of neutrophil-lymphocyte ratio and monocyte-lymphocyte ratio in preeclampsia

(2019) Jing Wang et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immune imbalance is associated with the development of preeclampsia

(2019) Yu Ma et al.   MEDICINE

Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia

(2019) Mariana Leticia Matias et al.   MOLECULES

Role of the Monocyte–Macrophage System in Normal Pregnancy and Preeclampsia

(2019) Polina Vishnyakova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adjuvant Strategies for More Effective Tuberculosis Vaccine Immunity

(2019) Stewart et al.   Microorganisms

Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies

(2019) Anandita Umapathy et al.   ANGIOGENESIS

Inflammasomes: Their Role in Normal and Complicated Pregnancies

(2019) Nardhy Gomez-Lopez et al.   JOURNAL OF IMMUNOLOGY

Distinct inflammatory profile in preeclampsia and postpartum preeclampsia reveal unique mechanisms

(2018) Marie-Eve Brien et al.   BIOLOGY OF REPRODUCTION

Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts

(2018) G. S. Stødle et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Induction of systemic inflammation by hyaluronan and hsp70 in women with pre-eclampsia

(2018) Mariana Romão-Veiga et al.   CYTOKINE

Oxidative Stress in Preeclampsia and Placental Diseases

(2018) Rajaa Aouache et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Angiogenic and antiangiogenic factors in preeclampsia

(2018) Fernanda Rodrigues Helmo et al.   PATHOLOGY RESEARCH AND PRACTICE

Oxidative stress in placental pathology

(2018) Mirthe H. Schoots et al.   PLACENTA

Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs

(2018) Yifei Wang et al.   JOURNAL OF IMMUNOLOGY

Distribution of monocyte subsets and polarization in preeclampsia and intrauterine fetal growth restriction

(2018) Thushari I. Alahakoon et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Alarmins of the extracellular space

(2018) Jenna L. Dziki et al.   SEMINARS IN IMMUNOLOGY

Hydrogen peroxide-mediated oxidative stress induces inflammasome activation in term human placental explants

(2018) Priscila Rezeck Nunes et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Oxidative stress: Normal pregnancy versus preeclampsia

(2018) Delia I. Chiarello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Association between cytokine profile and transcription factors produced by T-cell subsets in early- and late-onset pre-eclampsia

(2017) Vanessa R. Ribeiro et al.   IMMUNOLOGY

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

(2017) Leslie Freeman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes duringToxoplasma gondiiInfection

(2017) Lanny Gov et al.   JOURNAL OF IMMUNOLOGY

Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2017) Gilad Doitsh et al.   NATURE

Emerging role for dysregulated decidualization in the genesis of preeclampsia

(2017) Kirk P. Conrad et al.   PLACENTA

β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares

(2017) Emily L. Goldberg et al.   Cell Reports

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

(2016) John V. Ilekis et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

(2016) Christina J. Groß et al.   IMMUNITY

Oxidative stress and the evolutionary origins of preeclampsia

(2016) Michael G. Elliot   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Pre-eclampsia

(2016) Ben W J Mol et al.   LANCET

Morphological changes of placental syncytium and their implications for the pathogenesis of preeclampsia

(2015) Cynthia S. Roland et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast

(2015) Monika Siwetz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Nitric Oxide and Reactive Oxygen Species in the Pathogenesis of Preeclampsia

(2015) Keiichi Matsubara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

(2015) Elena Viganò et al.   Nature Communications

Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling

(2015) Robyn D. Pereira et al.   Biomed Research International

Oxidative stress in preeclampsia and the role of free fetal hemoglobin

(2015) Stefan R. Hansson et al.   Frontiers in Physiology

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome

(2014) M. Kool et al.   JOURNAL OF IMMUNOLOGY

Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia

(2014) Hong Wa Yung et al.   JOURNAL OF PATHOLOGY

Functional Toll-like receptors in primary first-trimester trophoblasts

(2014) Line H. Tangerås et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Endothelial dysfunction and preeclampsia: role of oxidative stress

(2014) Lissette C. Sánchez-Aranguren et al.   Frontiers in Physiology

The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP

(2014) A.L. Tranquilli et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Human Placental Mesenchymal Stem Cells (pMSCs) Play a Role as Immune Suppressive Cells by Shifting Macrophage Differentiation from Inflammatory M1 to Anti-inflammatory M2 Macrophages

(2013) M. H. Abumaree et al.   Stem Cell Reviews and Reports

Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms

(2013) Balaraman Kalyanaraman   Redox Biology

Systemic inflammatory stimulation by microparticles derived from hypoxic trophoblast as a model for inflammatory response in preeclampsia

(2012) Seung Mi Lee et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Fibrinolytic system in preeclampsia

(2012) M.B. Pinheiro et al.   CLINICA CHIMICA ACTA

Analysis of the original causes of placental oxidative stress in normal pregnancy and pre-eclampsia: A hypothesis

(2012) Xiang Yang et al.   Journal of Maternal-Fetal & Neonatal Medicine

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Stress and Antioxidant Defense

(2012) Esra Birben et al.   World Allergy Organization Journal

Role of oxidative stress and antioxidant supplementation in pregnancy disorders

(2011) Lucilla Poston et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Uric Acid Induces Trophoblast IL-1β Production Via the Inflammasome: Implications for the Pathogenesis of Preeclampsia

(2011) Melissa J. Mulla et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Immunology of Pre-Eclampsia

(2010) Christopher W. G. Redman et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia

(2010) F Xie et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array

(2010) Andras Szarka et al.   BMC IMMUNOLOGY

Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy

(2010) Pardeep Kumar Aggarwal et al.   HYPERTENSION RESEARCH

Role of nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia

(2010) Keiichi Matsubara et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia

(2009) Attila Molvarec et al.   CELL STRESS & CHAPERONES

Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies

(2009) Attila Molvarec et al.   CELL STRESS & CHAPERONES

Preeclampsia is associated with decreased serum α2-HS glycoprotein (fetuin-A) concentration

(2009) Attila Molvarec et al.   HYPERTENSION RESEARCH

Cytokine gene polymorphisms in preeclampsia and eclampsia

(2009) Telmo H Barbosa de Lima et al.   HYPERTENSION RESEARCH

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Vascular biology of preeclampsia

(2008) L. MYATT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS