Article
Chemistry, Medicinal
Dakyung Kim, Minhee Lee, Joo Hwan Yang, Joon Sung Yang, Ok-Kyung Kim
Summary: In this study, the protective effects of low-molecular-weight fish collagen from tilapia against melanogenesis and photoaging were investigated. The results showed that low-molecular-weight fish collagen activated collagen production-related pathways and suppressed melanogenesis-related pathways. This collagen also exhibited anti-inflammatory, antioxidant, and anti-melanogenesis activities, providing a potential natural anti-photoaging product.
JOURNAL OF MEDICINAL FOOD
(2022)
Review
Chemistry, Medicinal
Ratih Pangestuti, Kyung-Hoon Shin, Se-Kwon Kim
Summary: Seaweeds are considered as potential sources of bioactive metabolites with unique structural and functional features, which have proven useful in the skincare and cosmetic industries. Studies have shown that these bioactive compounds exhibit potential anti-photoaging properties.
Article
Engineering, Chemical
Min Jeong Kim, Seo Yeon Shin, Nu Ri Song, Sunoh Kim, Sang Ouk Sun, Kyung Mok Park
Summary: In this study, the potential of Pueraria thunbergiana leaf extract as a natural ingredient for skin whitening and anti-aging functional cosmetics was confirmed. The ethyl acetate (EtOAc) fraction of the extract showed superior antioxidant activity, anti-melanogenesis, and antiphotoaging effects compared to other fractions. It was also found to protect against UVB damage and promote collagen synthesis.
Article
Plant Sciences
Xingyu Tao, Xuan Hu, Tongchuan Wu, Dongyue Zhou, Di Yang, Xue Li, Yunhua Fu, Fei Zheng, Hao Yue, Yulin Dai
Summary: The flavonoids and polysaccharides in Portulaca oleracea L. have antibacterial and antioxidant effects. A polysaccharide fraction (VPOP3) was found to have anti-photoaging and whitening activity by reducing apoptosis and regulating melanogenesis signaling pathways.
Article
Biochemistry & Molecular Biology
Kyoung Mi Moon, Ju-Hye Yang, Min-Kyeong Lee, Eun-Bin Kwon, Jiwon Baek, Taehyeok Hwang, Jae-Il Kim, Bonggi Lee
Summary: This study found that maclurin has inhibitory effects on melanogenesis and can be used as an anti-melanogenic agent.
Article
Biotechnology & Applied Microbiology
Yali Zhou, Renao Bai, Yifeng Huang, Weina Li, Jiana Chen, Zhiyun Cheng, Xunxun Wu, Yong Diao
Summary: This study investigated the potential protective effects of C-phycocyanin (C-PC) on UVB-induced skin aging using molecular biology tools. The results showed that C-PC has significant anti-aging activity and can improve the macroscopic features of mouse skin under UVB irradiation, as well as reduce epidermal thickening and prevent dermal collagen fiber loosening.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Shichao Wan, Yannan Liu, Jingjing Shi, Daidi Fan, Binglin Li
Summary: The study found that ginsenoside Rk3, as an active component, can protect skin health by inhibiting photoaging and inflammation. Through experiments in which it was mixed with cream and applied to the skin of mice, the G-Rk3 cream was found to make the skin smooth and plump, and to slow or halt the changes in various biomarker levels associated with skin aging and inflammation.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Kyuri Kim, YoonJung Huh, Kyung-Min Lim
Summary: Hyper-activated melanocytes are the main cause of skin hyper-pigmentary disorders, leading to a high demand for anti-pigmentary natural compounds without toxicity concerns. Research has focused on finding such compounds from various natural sources, including the ocean, plants, and bacteria.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Huizhen Chen, Ying Li, Xinqiang Xie, Moutong Chen, Liang Xue, Juan Wang, Qinghua Ye, Shi Wu, Runshi Yang, Hui Zhao, Jumei Zhang, Yu Ding, Qingping Wu
Summary: The study found that nicotinamide (NAM) derived from a strain of lactic acid bacteria (LAB) can protect the skin from UV-induced damage by stabilizing mitochondrial function, suggesting its potential as a preventive measure against photoaging.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Review
Food Science & Technology
Wanzi Yao, Xiaoyong Chen, Xiong Li, Shiyuan Chang, Mouming Zhao, Lijun You
Summary: Photoaging is a complex process triggered by UV radiation, causing changes in skin appearance and function, ultimately leading to skin cancer. Non-starch polysaccharides from natural resources are believed to have anti-photoaging effects, but research on this topic is still limited.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Medicinal
Songzhi Kong, Lijiao Lv, Jiaqi Guo, Xiaohong Yang, Mingneng Liao, Tianyang Zhao, Haiyang Sun, Shuqun Zhang, Wenjie Li
Summary: A gel composed of chitosan, sodium beta-glycerophosphate, and small molecular CSCPs was prepared and found to effectively inhibit UV-induced skin aging and improve skin moisture content. It inhibited epidermal thickening, reduced tissue inflammation, suppressed collagen fiber degradation, and increased collagen content. The gel also inhibited the expression of ROS and proinflammatory factors while promoting the expression of the anti-inflammatory factor IL-10.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Article
Medicine, Research & Experimental
Tomohisa Yoshimura, Chika Manabe, Yuki Inokuchi, Chikako Mutou, Tohru Nagahama, Shigeru Murakami
Summary: This study showed that oral supplementation with taurine can suppress UVB-induced wrinkle formation by regulating moisture content in the epidermis, suggesting potential beneficial effects of taurine on skin aging.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Nutrition & Dietetics
Hao Fu, Yuzhi Zhang, Quan An, Dongdong Wang, Shiquan You, Dan Zhao, Jiachan Zhang, Changtao Wang, Meng Li
Summary: The study found that Lactobacillus plantarum fermented Rhodiola rosea has better antioxidant and anti-photoaging abilities, reducing oxidative stress and improving antioxidant levels. It also protects cells from UVA-induced damage by activating signaling pathways and increasing collagen and elastin.
Article
Plant Sciences
Woo Sik Kim, Jeong Hun Seo, Jae-In Lee, Eun-Sil Ko, Sang-Min Cho, Jea-Ran Kang, Jong-Hoon Jeong, Yu Jeong Jeong, Cha Young Kim, Jeong-Dan Cha, Young-Bae Ryu
Summary: The study demonstrated the potential of Aster yomena extract in reducing photoaging effects on human keratinocytes, and improving skin conditions related to inflammation, skin damage recovery, and moisture retention. This suggests the use of AYC-CS-E as a cosmetic ingredient for various skin diseases caused by photoaging, highlighting the commercial potential of the callus culture system for cosmetic ingredients supply.
Article
Engineering, Chemical
En-Ting Lin, Yi-Chieh Lee, Hui-Min David Wang, Chen-Yaw Chiu, Yu-Kaung Chang, Chun-Yung Huang, Chia-Che Chang, Pei-Chien Tsai, Jo-Shu Chang
Summary: Fucoidan is a polysaccharide with excellent antioxidant, anti-inflammatory, anti-angiogenic, antitumor, and antibacterial capabilities. Subcritical water extraction is an effective method for extracting fucoidan and preserving its bioactivity.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2022)
Review
Food Science & Technology
Thilina U. Jayawardena, Seo-Young Kim, You-Jin Jeon
Summary: This review addresses the current understanding of age-related skeletal muscle changes and discusses mechanisms regulating protein turnover, as well as the factors contributing to reduced muscle regeneration. Nutritional intervention, particularly seafood, is highlighted as a potential preventive factor against sarcopenia. Understanding multiple factors will provide therapeutic targets for preventing, treating, and overcoming the adverse effects of sarcopenia.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biotechnology & Applied Microbiology
Jimin Hyun, Hye-Won Yang, Jun-Geon Je, Hyo-Geun Lee, Gwang Hoon Kim, You-Jin Jeon
Summary: Increased oceanic temperature is affecting the production of Pyropia yezoensis in South Korea, leading to a decrease in its global supply. This study explores the antioxidant properties of a newly developed heat-resistant P. yezoensis and its enzymatically hydrolyzed fractions, showing potential as a nutraceutical antioxidant. The hydrolysate containing the highest protein content displayed significant protection against oxidative stress in cells and embryos.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Food Science & Technology
Hyo-Geun Lee, Min-Cheol Kang, You-Jin Jeon, Young-Sang Kim
Summary: This study investigated the In vitro lipid inhibitory effects of sulfated polysaccharide fractions derived from Sargassum thunbergii and found that it has a beneficial effect on intracellular lipid metabolism, suggesting its potential as a functional ingredient in the functional food industry.
Article
Food Science & Technology
Hyo-Geun Lee, You-Jin Jeon, Min-Cheol Kang
Summary: This study investigated the lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. The results showed that the compounds significantly reduced intracellular lipid accumulation and had profound anti-obesity effects on high fat diet-fed obesity model mice. These effects were achieved by regulating adipogenesis, lipolysis, and fatty acid oxidation pathways.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Chemistry, Medicinal
H. H. A. C. K. Jayawardhana, Thilina U. Jayawardena, K. K. A. Sanjeewa, N. M. Liyanage, D. P. Nagahawatta, Hyo-Geun Lee, Jae-Il Kim, You-Jin Jeon
Summary: The skin, as the outermost anatomical barrier, is important for maintaining internal homeostasis and protecting against various threats. The use of natural ingredients, particularly polyphenolic compounds derived from marine macroalgae, is gaining attention in the cosmetic industry due to concerns about synthetic compounds. These compounds have demonstrated promising biological activities, making them potential candidates for a wide range of cosmetic applications. This review highlights the beneficial properties and future prospects of utilizing marine macroalgae-derived polyphenolic compounds in advancing the cosmetic industry.
Article
Polymer Science
Lei Wang, Jae-Young Oh, Hye-Won Yang, Jimin Hyun, Ginnae Ahn, Xiaoting Fu, Jiachao Xu, Xin Gao, Seon-Heui Cha, You-Jin Jeon
Summary: This study evaluated the protective effect of fucoidan from Sargassum fusiforme against ethanol-induced oxidative damage. Results showed that fucoidan effectively decreased the damage to liver cells and increased the survival rate of zebrafish. These findings suggest the potential of fucoidan as an ingredient in the functional food industry.
Article
Polymer Science
Lei Wang, Xiaoting Fu, Jimin Hyun, Jiachao Xu, Xin Gao, You-Jin Jeon
Summary: In this study, the anti-inflammatory and antioxidant activities of agaro-oligosaccharides (AO) from Gracilaria lemaneiformis were investigated. AO showed significant scavenging abilities for various radicals and protected cells against oxidative damage. In vivo experiments demonstrated that AO reduced intracellular reactive oxygen species levels and lipid peroxidation in zebrafish, suggesting its potential applications in cosmetics and functional foods.
Article
Food Science & Technology
D. P. Nagahawatta, N. M. Liyanage, Thilina U. Jayawardena, H. H. A. C. K. Jayawardhana, Jae-Young Oh, K. K. Asanka Sanjeewa, Sang In Kang, You-Jin Jeon
Summary: The study found that digested flounder meat has the potential to promote skeletal muscle growth and can be used as a functional food ingredient.
Review
Biology
N. M. Liyanage, D. P. Nagahawatta, Thilina U. U. Jayawardena, You-Jin Jeon
Summary: Inflammatory bowel disease (IBD) is a global public health issue. Current treatments such as anti-inflammatory medications and immunosuppressants have limitations, leading to a demand for natural substances like seaweed polysaccharides. The study reviewed the potential therapeutic effects of algal polysaccharides on IBD and highlighted their significant potential in complementary IBD therapy.
Review
Chemistry, Medicinal
N. M. Liyanage, D. P. Nagahawatta, Thilina U. Jayawardena, Kalu Kapuge Asanka Sanjeewa, H. H. A. C. K. Jayawrdhana, Jae-Il Kim, You-Jin Jeon
Summary: Seaweed polysaccharides have shown great potential as a source of antiviral agents for the treatment of viral diseases. They inhibit viral infections through various mechanisms, including interfering with DNA or RNA synthesis, viral entry, and replication. However, the development of polysaccharide-based antiviral therapies still faces challenges such as drug delivery and formulation.
Article
Polymer Science
Lei Wang, Thilina U. Jayawardena, Young-Sang Kim, Kaiqiang Wang, Xiaoting Fu, Ginnae Ahn, Seon-Heui Cha, Jeong Gyun Kim, Jung Suck Lee, You-Jin Jeon
Summary: Sulfated polysaccharides isolated from seaweeds are considered ideal ingredients in the pharmaceutical, nutraceutical, and cosmetics industries. Our previous study isolated and characterized sulfated polysaccharides from Padina boryana. The results indicate that these polysaccharides possess antioxidant effects and potential in the cosmetic industry.
Article
Biochemistry & Molecular Biology
Jimin Hyun, Sang-In Kang, Sang-Woon Lee, R. P. G. S. K. Amarasiri, D. P. Nagahawatta, Yujin Roh, Lei Wang, Bomi Ryu, You-Jin Jeon
Summary: This research investigates the potential of enzymatic hydrolysis of olive flounder by-products (OFB) to produce functional ingredients. Various enzymatic hydrolysates of OFB (OFBEs) were generated using 11 commercial enzymes, and OFBEs showed enhanced physiological usability and muscle regenerative potential, particularly with Prozyme 2000P-assisted OFBE (OFBP).
