IRF1 Promotes the Innate Immune Response to Viral Infection by Enhancing the Activation of IRF3

Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses

(2019) Daisuke Yamane et al.   Nature Microbiology

Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation

(2019) Yumei Zhou et al.   CELL RESEARCH

The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1–IRF3 signaling

(2018) Hua Zhang et al.   Cellular & Molecular Immunology

LncITPRIP-1 Positively Regulates Innate Immune Response through Promoting Oligomerization and Activation of MDA5

(2018) Qinya Xie et al.   JOURNAL OF VIROLOGY

TRIM21 Promotes Innate Immune Response to RNA Viral Infection through Lys27-Linked Polyubiquitination of MAVS

(2018) Binbin Xue et al.   JOURNAL OF VIROLOGY

Cellular and molecular regulation of innate inflammatory responses

(2016) Juan Liu et al.   Cellular & Molecular Immunology

IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes

(2016) Lei Xu et al.   FASEB JOURNAL

A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation

(2016) Di Peng et al.   JOURNAL OF IMMUNOLOGY

TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

(2015) Peng Wang et al.   PLoS Pathogens

The regulation role of interferon regulatory factor-1 gene and clinical relevance

(2014) Lei Dou et al.   HUMAN IMMUNOLOGY

Recruitment of Phosphatase PP2A by RACK1 Adaptor Protein Deactivates Transcription Factor IRF3 and Limits Type I Interferon Signaling

(2014) Lingyun Long et al.   IMMUNITY

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

(2014) Charlotte Odendall et al.   NATURE IMMUNOLOGY

Complete replication of hepatitis B virus and hepatitis C virus in a newly developed hepatoma cell line

(2014) Darong Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3

(2013) Cao-Qi Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

(2013) Iris F. Ueki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of IFN- 1 Promoter Activity (IFN- 1/IL-29) in Human Airway Epithelial Cells

(2011) R. Siegel et al.   JOURNAL OF IMMUNOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

(2008) Min Zhang et al.   CELL RESEARCH