Review
Clinical Neurology
Shuwen Mu, Yi Fang, Zhijie Pei, Yinghong Lin, Kunzhe Lin, Zihuan Zeng, Longmin Zhou, Zhengjun Wang, Shousen Wang
Summary: This study found that preinjury statin use in patients with TBI is associated with a decreased risk of mortality, while statin withdrawal may increase mortality. These results highlight the importance of continued statin use in patients with TBI.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Pal Ronning, Eirik Helseth, Ola Skaansar, Cathrine Tverdal, Nada Andelic, Rahul Bhatnagar, Mathias Melberg, Nils Oddvar Skaga, Mads Aarhus, Sigrun Halvorsen, Ragnhild Helseth
Summary: A retrospective study on 832 elderly traumatic brain injury (TBI) patients found that the use of antiplatelets or anticoagulants alone did not increase 30-day mortality, but combined use posed a higher risk of death. Compared to the general Norwegian population, TBI patients were more likely to use anticoagulant drugs, potentially leading to intracranial bleeding. There was no significant difference in 30-day mortality between patients using VKA, DOACs, or LMWH.
FRONTIERS IN NEUROLOGY
(2021)
Review
Clinical Neurology
Li Cheng, Gaoliang Cui, Rong Yang
Summary: The study found that traumatic brain injury patients on pre-injury antiplatelet drugs did not have significantly worse early mortality rates compared to those not on any antiplatelet or anticoagulant drugs. The use of antiplatelets was not associated with an increased need for neurosurgical intervention or prolonged hospital stay.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, General & Internal
Sol Bi Kim, Youngjoon Park, Ju Won Ahn, Jeongmin Sim, Jeongman Park, Yu Jin Kim, So Jung Hwang, Kyoung Su Sung, Jaejoon Lim
Summary: This study created a prediction model for the survival of patients with TBI by adding hematologic parameters to existing non-hematologic parameters. The model showed high accuracy in predicting mortality in TBI patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medical Laboratory Technology
Yaokun Zhuang, Wenhua Wang, Long Chen, Wei Lu, Min Xu
Summary: The study demonstrates that serum Apelin-13 concentration may serve as a prognostic biomarker for severe traumatic brain injury. The decline in serum Apelin-13 concentration is closely associated with increasing severity and can independently predict short-term mortality in patients with sTBI.
CLINICA CHIMICA ACTA
(2021)
Article
Medicine, General & Internal
Anna Antoni, Lukas Wedrich, Martin Schauperl, Leonard Hoechtl-Lee, Irene K. Sigmund, Markus Gregori, Johannes Leitgeb, Elisabeth Schwendenwein, Stefan Hajdu
Summary: This retrospective study analyzed data of head trauma patients using antithrombotic therapy and found that patients using direct oral anticoagulants (DOAC) had similar risks of pathological CT findings, delayed intracranial hemorrhage, surgical interventions, and death compared to those using vitamin K antagonists (VKA). However, DOAC patients had a lower risk of pathological CT findings compared to patients using platelet inhibitors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Rory B. O'Donohoe, Hui Qing Lee, Terence Tan, Simon Hendel, Martin Hunn, Joseph Mathews, Mark Fitzgerald, Jeffrey Rosenfeld, Jin Tee
Summary: This study examines the impact of preinjury anticoagulant and antiplatelet therapy on acute subdural hematoma (aSDH) in elderly patients. The results show that preinjury antithrombotic use is associated with a statistically significant difference in aSDH thickness, but there are no significant differences in 30-day mortality and unfavorable outcome at 6 months.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Rory B. O'Donohoe, Hui Qing Lee, Terence Tan, Simon Hendel, Martin Hunn, Joseph Mathews, Mark Fitzgerald, Jeffrey V. Rosenfeld, Jin Tee
Summary: Although there was a significant difference in the mean aSDH thickness, there were no significant differences in 30-day mortality and unfavorable outcomes between the groups exposed to AP, AC, combined AP and AC, and no antithrombotic treatment. More studies with larger sample sizes are needed to confirm these observations, but the findings do not support the common belief that antithrombotic use leads to poorer outcomes in elderly patients with moderate or severe TBI.
WORLD NEUROSURGERY
(2022)
Article
Health Care Sciences & Services
Min Chao, Chia-Cheng Wang, Carl P. C. Chen, Chia-Ying Chung, Chun-Hsiang Ouyang, Chih-Chi Chen
Summary: Severe traumatic brain injury (sTBI) is a major cause of death in children, often accompanied by serious extracranial injury (SEI). This study analyzed the clinical characteristics and initial presentations of SEI, and found that sTBI children with SEI had a higher in-hospital mortality rate. However, SEI itself was not an independent predictor of mortality.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biology
Dorota Siwicka-Gieroba, Wojciech Dabrowski
Summary: Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide, with the neutrophil-to-lymphocyte ratio (NLR) potentially serving as a low-cost, objective predictor of inflammation and marker of secondary injury associated with neutrophil activation.
Article
Medicine, General & Internal
Jesus Abelardo Barea-Mendoza, Mario Chico-Fernandez, Manuel Quintana-Diaz, Lluis Servia-Goixart, Ana Fernandez-Cuervo, Maria Bringas-Bollada, Maria Angeles Ballesteros-Sanz, Iker Garcia-Saez, Jon Perez-Barcena, Juan Antonio Llompart-Pou
Summary: The aim of this study was to analyze the impact of acute kidney injury (AKI) on mortality in patients with isolated traumatic brain injury (TBI) and identify associated risk factors. The results showed that 10.6% of patients developed AKI, which was significantly associated with increased mortality. Age, hemodynamic instability, rhabdomyolysis, trauma-associated coagulopathy, and transfusion of packed red-blood-cell concentrates were identified as the main risk factors for AKI in isolated TBI patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Letter
Surgery
W. Ian Mckinley, Susan E. Rowell, Ali Mansour, Lea Hoefer, Ann Polcari, Martin Schreiber, Andrew J. Benjamin
Summary: This cohort study investigates the relationship between tranexamic acid administration and intracranial hemorrhage type, neurologic outcomes, and mortality in patients with traumatic brain injury.
Article
Medicine, General & Internal
Alessandro Cipriano, Gianni Turcato, Naria Park, Arian Zaboli, Greta Barbieri, Alessandro Riccardi, Massimo Santini, Roberto Lerza, Antonio Bonora, Lorenzo Ghiadoni
Summary: Currently, all patients on oral anticoagulant therapy should have a head CT regardless of the type of head injury. This study compared the incidence of intracranial hemorrhage (ICH) between patients with minor head injury (mHI) and mild traumatic brain injury (MTBI) and assessed the risk of death or neurosurgery at 30 days. Data from a retrospective multicenter study between 2016 and 2020 was analyzed, and patients on DOACs therapy who suffered head trauma and underwent a head CT were included. The study found that patients with MTBI had a higher incidence of ICH and a higher risk of death or neurosurgery compared to patients with mHI.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Xue-Yan Zheng, Qian Yi, Xiao-Jun Xu, Rui-Lin Meng, Shu-Li Ma, Si-Li Tang, Hao-Feng Xu, Ying-Shan Xu, Yan-Jun Xu, Yi Yang
Summary: The study found that traumatic brain injury mortality remained relatively stable, while spinal cord injury mortality increased significantly from 2014 to 2018. Males, rural residents, and older individuals had higher adjusted mortality rate ratios for both TBI and SCI. Motor vehicle crashes and falls were the leading causes of TBI mortality, while falls were the most important external cause of SCI death across all ages.
Article
Clinical Neurology
Leonardo Lorente, Maria M. Martin, Antonia Perez-Cejas, Agustin F. Gonzalez-Rivero, Luis Ramos-Gomez, Jordi Sole-Violan, Juan J. Caceres, Carmen Ferrer-Moure, Alejandro Jimenez
Summary: The study aimed to investigate the association between blood caspase-8 concentrations and mortality in traumatic brain injury (TBI) patients. Results showed that surviving patients had differences in age, Glasgow Coma Scale, disease severity score, head CT findings, intracranial pressure, and serum caspase-8 concentrations compared to non-surviving patients.
NEUROLOGICAL SCIENCES
(2021)
Letter
Gastroenterology & Hepatology
Shahab Hajibandeh, Shahin Hajibandeh, Alwin Puthiyakunnel Saji
COLORECTAL DISEASE
(2023)
Article
Surgery
Shahin Hajibandeh, Shahab Hajibandeh, Syed Soulat Raza, David Bartlett, Bobby V. M. Dasari, Robert P. Sutcliffe
Summary: A systematic review and meta-analysis of seven randomized controlled trials revealed that abdominal drainage after hepatectomy increases overall and wound-related complications without reducing the risk of intervention-requiring intra-abdominal collections. Routine drainage should be avoided in uncomplicated hepatectomy, except for cases with bilioenteric anastomosis.
Review
Surgery
Louis Evans, Shahin Hajibandeh, Shahab Hajibandeh
Summary: A systematic review comparing the outcomes of sac invagination and sac ligation in open Lichtenstein repair of indirect inguinal hernia was conducted. The results showed that there was no difference in terms of recurrence, chronic pain, and operative complications between the two techniques. However, sac ligation resulted in more early postoperative pain.
Letter
Anesthesiology
S. Hajibandeh
Letter
Surgery
Shahin Hajibandeh, Shahab Hajibandeh
ANZ JOURNAL OF SURGERY
(2023)
Review
Gastroenterology & Hepatology
Shahab Hajibandeh, Shahin Hajibandeh, Matthew McKenna, William Jones, Paul Healy, Jolene Witherspoon, Guy Blackshaw, Wyn Lewis, Antonio Foliaki, Tarig Abdelrahman
Summary: This study aimed to evaluate the effect of intraoperative botulinum toxin (BT) injection on delayed gastric emptying (DGE) and need for endoscopic pyloric intervention (NEPI) following esophagectomy. A systematic review was conducted to assess the outcomes of BT injection in patients undergoing esophagectomy for esophageal cancer. The results showed that BT injection did not improve the risk of DGE and NEPI compared to no BT injection or surgical pyloroplasty. However, the risk of DGE seemed to be higher in females and in the early postoperative period. Further high quality randomized controlled trials are needed for definitive conclusions.
DISEASES OF THE ESOPHAGUS
(2023)
Review
Gastroenterology & Hepatology
Shahab Hajibandeh, Rebecca Jurdon, Emily Heaton, Shahin Hajibandeh, David O'Reilly
Summary: This study aimed to determine and quantify the risk of recurrent pancreatitis after the first episode of acute pancreatitis in relation to etiology and severity of disease. Analysis of 57,815 patients from 42 studies showed that the risk of recurrent pancreatitis was affected by the etiology but not the severity of pancreatitis. The risks were higher in patients with autoimmune pancreatitis, hyperlipidemia-induced pancreatitis, and alcohol-induced pancreatitis, and lower in patients with gallstone pancreatitis and idiopathic pancreatitis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Shahin Hajibandeh, Shahab Hajibandeh, Saleh Romman, Alessandro Parente, Richard W. Laing, Thomas Satyadas, Daren Subar, Somaiah Aroori, Anand Bhatt, Damien Durkin, Tejinderjit S. Athwal, Keith J. Roberts
Summary: This study evaluated the ability of CAR to predict outcomes in patients undergoing pancreatic cancer resection. Eight studies with a total of 1056 patients were identified. Higher CAR values were found to be independent and significant predictors of poor overall survival in these patients. However, the determination of an optimal cut-off value for CAR is currently unclear due to heterogeneity in reporting.
Review
Surgery
V. Satish Kolli, K. Kumar, S. Hajibandeh, S. Hajibandeh
Summary: This study compared the outcomes of balloon dissection and telescopic dissection in patients undergoing laparoscopic TEP inguinal hernia repair. A total of 936 patients from eight studies were included. The results showed no difference between the two techniques in terms of operative and postoperative outcomes. Cost-effectiveness analysis in future studies may play a role in determining the preferred dissection technique.
Review
Surgery
A. Y. Y. Mohamedahmed, S. Zaman, N. Ghassemi, A. Ghassemi, A. A. Wuheb, H. E. E. Abdalla, S. Hajibandeh, S. Hajibandeh
Summary: The available evidence does not support the routine use of surgical drains during ventral hernia repairs. The use of drains is associated with increased risk of surgical site infections and longer operative time, but does not have significant advantages in terms of wound-related complications.
Review
Surgery
Trish Duncan, Shahab Hajibandeh, Shahin Hajibandeh, Murhaf Assaf, Giorgio Alessandri, Nagappan Kumar, David O'Reilly
Summary: This study aimed to determine the risk of hepatic pseudoaneurysm after liver trauma in relation to the severity of liver injury. The results showed that the risk of hepatic pseudoaneurysm increases as the severity of liver injury increases.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Review
Biochemistry & Molecular Biology
Shahab Hajibandeh, Christina Intrator, Eliot Carrington-Windo, Rhodri James, Ioan Hughes, Shahin Hajibandeh, Thomas Satyadas
Summary: The END-PAC model shows promising performance in predicting pancreatic cancer risk in individuals with new-onset diabetes, with a score >= 3 being the optimal cut-off value. This model may improve early detection rate and treatment outcomes of pancreatic cancer, but further studies are needed.
Review
Surgery
Elizabeth Forshaw, Shahin Hajibandeh, Shahab Hajibandeh
Summary: The study investigates the effect of postoperative ghrelin therapy on postoperative inflammatory response and bodyweight loss in patients undergoing oesophagectomy for oesophageal cancer. The findings suggest that ghrelin therapy can reduce the duration of postoperative systemic inflammatory response syndrome (SIRS) and bodyweight loss.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
