A computer-simulated mechanism of familial Alzheimer’s disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase

Published 2020 View Full Article

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Title
A computer-simulated mechanism of familial Alzheimer’s disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase
Authors
Keywords
γ-Secretase, Alzheimer’s disease, Presenilin, Mutation, Molecular dynamics
Journal
JOURNAL OF STRUCTURAL BIOLOGY
Volume -, Issue -, Pages 107648
Publisher
Elsevier BV
Online
2020-10-21
DOI
10.1016/j.jsb.2020.107648

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