August Krogh's theory of muscle microvascular control and oxygen delivery: a paradigm shift based on new data

Reply to Letter to the Editor: Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo

(2020) P. Mason McClatchey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo

(2020) Michelle A. Keske et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of vascular function on exercise capacity in health and disease

(2020) David C. Poole et al.   JOURNAL OF PHYSIOLOGY-LONDON

August Krogh: physiology genius and compassionate humanitarian

(2020) David C. Poole et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pericyte constriction underlies capillary de-recruitment during hyperemia in the setting of arterial stenosis

(2019) Carmen Methner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Delineating the age-related attenuation of vascular function:Evidence supporting the efficacy of the single passive leg movement technique.

(2019) Jay R. Hydren et al.   JOURNAL OF APPLIED PHYSIOLOGY

EDWARD F. ADOLPH DISTINGUISHED LECTURE. CONTEMPORARY MODEL OF MUSCLE MICROCIRCULATION: GATEWAY TO FUNCTION AND DYSFUNCTION

(2019) David C. Poole   JOURNAL OF APPLIED PHYSIOLOGY

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

(2019) Amy E. Vincent et al.   Cell Reports

Perfusion Controls Muscle Glucose Uptake by Altering the Rate of Glucose Dispersion In Vivo

(2019) P. Mason McClatchey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Capillary Facilitation of Skeletal Muscle Function in Health and Disease

(2019) Gianni Parise et al.   Applied Physiology Nutrition and Metabolism

Metabolic‐vascular coupling in skeletal muscle: A potential role for capillary pericytes?

(2019) Emily Attrill et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Krogh’s capillary recruitment hypothesis, 100 years on: Is the opening of previously closed capillaries necessary to ensure muscle oxygenation during exercise?

(2019) Hugo Angleys et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sex and nitric oxide bioavailability interact to modulate interstitial Po2 in healthy rat skeletal muscle

(2018) Jesse C. Craig et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal muscle microvascular and interstitial PO2 from rest to contractions

(2018) Daniel M. Hirai et al.   JOURNAL OF PHYSIOLOGY-LONDON

Skeletal muscle interstitial O2 pressures: bridging the gap between the capillary and myocyte

(2018) Daniel M Hirai et al.   MICROCIRCULATION

Managing the power grid: how myoglobin can regulate PO2 and energy distribution in skeletal muscle

(2018) Thomas L. Clanton   JOURNAL OF APPLIED PHYSIOLOGY

Increased cortical capillary transit time heterogeneity in Alzheimer's disease: a DSC-MRI perfusion study

(2017) Simon F. Eskildsen et al.   NEUROBIOLOGY OF AGING

Capillary pericytes mediate coronary no-reflow after myocardial ischaemia

(2017) Fergus M O'Farrell et al.   eLife

Exercise training in chronic heart failure: improving skeletal muscle O2 transport and utilization

(2015) Daniel M. Hirai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of skeletal muscle capillary growth in exercise and disease

(2015) Tara L. Haas et al.   Applied Physiology Nutrition and Metabolism

Capillary Dysfunction: Its Detection and Causative Role in Dementias and Stroke

(2015) Leif Østergaard et al.   Current Neurology and Neuroscience Reports

Heterogeneity of Muscle Blood Flow and Metabolism

(2015) Ilkka Heinonen et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Muscle deoxygenation in the quadriceps during ramp incremental cycling: Deep vs. superficial heterogeneity

(2015) Dai Okushima et al.   JOURNAL OF APPLIED PHYSIOLOGY

Validation of a high-power, time-resolved, near-infrared spectroscopy system for measurement of superficial and deep muscle deoxygenation during exercise

(2015) Shunsaku Koga et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Effects of Transit Time Heterogeneity on Brain Oxygenation during Rest and Functional Activation

(2015) Peter M Rasmussen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondrial reticulum for cellular energy distribution in muscle

(2015) Brian Glancy et al.   NATURE

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

(2015) Robert A. Hill et al.   NEURON

The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease

(2014) Leif Østergaard et al.   BASIC RESEARCH IN CARDIOLOGY

Capillary Transit Time Heterogeneity and Flow-Metabolism Coupling after Traumatic Brain Injury

(2014) Leif Østergaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CrossTalk opposing view:De novocapillary recruitment in healthy muscle is not necessary to explain physiological outcomes

(2014) David C. Poole   JOURNAL OF PHYSIOLOGY-LONDON

Rebuttal from David C. Poole

(2014) David C. Poole   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk proposal:De novocapillary recruitment in healthy muscle is necessary

(2014) Eugene J. Barrett et al.   JOURNAL OF PHYSIOLOGY-LONDON

In VivoMicroscopy Reveals Extensive Embedding of Capillaries within the Sarcolemma of Skeletal Muscle Fibers

(2014) Brian Glancy et al.   MICROCIRCULATION

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Cardiac output response to exercise in relation to metabolic demand in heart failure with preserved ejection fraction

(2013) Muaz M. Abudiab et al.   EUROPEAN JOURNAL OF HEART FAILURE

Skeletal muscle capillary function: contemporary observations and novel hypotheses

(2013) David C. Poole et al.   EXPERIMENTAL PHYSIOLOGY

Are the precapillary sphincters and metarterioles universal components of the microcirculation? An historical review

(2013) Tatsuo Sakai et al.   Journal of Physiological Sciences

Dynamic Heterogeneity of Exercising Muscle Blood Flow and O2 Utilization

(2013) SHUNSAKU KOGA et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Comparison of Generated Parallel Capillary Arrays to Three-Dimensional Reconstructed Capillary Networks in Modeling Oxygen Transport in Discrete Microvascular Volumes

(2013) Graham M. Fraser et al.   MICROCIRCULATION

Bang-Bang Model for Regulation of Local Blood Flow

(2013) Aleksander S. Golub et al.   MICROCIRCULATION

Estimated contribution of hemoglobin and myoglobin to near infrared spectroscopy

(2013) Michelle L. Davis et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Microvascular Flow Modeling using In Vivo Hemodynamic Measurements in Reconstructed 3D Capillary Networks

(2012) GRAHAM M. FRASER et al.   MICROCIRCULATION

Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle

(2012) Gang Liu et al.   PLoS One

Oxygen gradients in the microcirculation

(2011) R. N. Pittman   Acta Physiologica

Mapping 3-D functional capillary geometry in rat skeletal muscle in vivo

(2011) Graham M. Fraser et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Muscle oxygen transport and utilization in heart failure: implications for exercise (in)tolerance

(2011) David C. Poole et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Roles of Cerebral Blood Flow, Capillary Transit Time Heterogeneity, and Oxygen Tension in Brain Oxygenation and Metabolism

(2011) Sune N Jespersen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of blood flow in the microcirculation: role of conducted vasodilation

(2010) P. Bagher et al.   Acta Physiologica

Dynamics of muscle microcirculatory and blood-myocyte O2 flux during contractions

(2010) D. C. Poole et al.   Acta Physiologica

Diffusive insights: on the disagreement of Christian Bohr and August Krogh at the Centennial of the Seven Little Devils

(2010) Albert Gjedde   ADVANCES IN PHYSIOLOGY EDUCATION

The physiological regulation of glucose flux into muscle in vivo

(2010) D. H. Wasserman et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Aging blunts the dynamics of vasodilation in isolated skeletal muscle resistance vessels

(2009) Bradley J. Behnke et al.   JOURNAL OF APPLIED PHYSIOLOGY

Last Word on Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise

(2008) David Poole et al.   JOURNAL OF APPLIED PHYSIOLOGY

Last Word on Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise

(2008) Michael Clark et al.   JOURNAL OF APPLIED PHYSIOLOGY

Counterpoint: There is not capillary recruitment in active skeletal muscle during exercise

(2008) David C. Poole et al.   JOURNAL OF APPLIED PHYSIOLOGY

Longitudinal and Radial Gradients of PO2in the Hamster Cheek Pouch Microcirculation

(2008) Helena Carvalho et al.   MICROCIRCULATION

The effects of aging on capillary hemodynamics in contracting rat spinotrapezius muscle

(2008) Steven W. Copp et al.   MICROVASCULAR RESEARCH

Rapid Vascular Responses to Muscle Contraction

(2007) Philip S. Clifford et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise

(2007) Michael G. Clark et al.   JOURNAL OF APPLIED PHYSIOLOGY

Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability

(2007) Max Nieuwdorp et al.   JOURNAL OF APPLIED PHYSIOLOGY

Muscle microvascular hemoglobin concentration and oxygenation within the contraction–relaxation cycle

(2007) Barbara J. Lutjemeier et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY