Article
Spectroscopy
J. L. Allen, T. J. Sanders, R. Plathe, D. Appadoo, J. Horvat, R. A. Lewis
Summary: Undiluted L-phenylalanine was cooled to 6K and its transmission spectrum was obtained under terahertz radiation, showing three distinct absorption bands that shift to lower frequencies with increasing temperature. A Bose-Einstein model can account for the temperature dependence, providing estimates for the zero-temperature frequency of each mode and the characteristic temperature of the associated phonon bath. The frequencies of all four modes, including a fourth band at 2.65THz, are in good agreement with a previous calculation.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Engineering, Environmental
Othman Y. Alothman, H. M. Shaikh, Basheer A. Alshammari, Mohammad Jawaid
Summary: The study successfully produced nano-sized lignocellulosic fillers from date palm micro fibers via mechanical ball milling process, and characterized them by various analytical techniques. The resulting nanofillers exhibited high heat resistance and stable thermo-changing behavior, making them suitable for composite fabrication at high temperature.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Biotechnology & Applied Microbiology
Jaewoo Son, Jun Hong Jang, In Hyeok Choi, Chang Gyu Lim, Eun Jung Jeon, Hyun Bae Bang, Ki Jun Jeong
Summary: This study successfully engineered Corynebacterium glutamicum as a whole-cell catalyst for the bioconversion of l-phenylalanine into trans-cinnamic acid (t-CA) with high efficiency, reaching a production yield of 75% through repetitive supplementation. The developed bioconversion process and micromembrane-based cell recycling system provide a promising platform for industrial-scale production of t-CA using microorganisms.
MICROBIAL CELL FACTORIES
(2021)
Article
Biochemistry & Molecular Biology
Vildan Sultanaev, Luidmila Yakimova, Anastasia Nazarova, Olga Mostovaya, Igor Sedov, Damir Davletshin, Elvina Gilyazova, Emil Bulatov, Zhang-Ting Li, Dan-Wei Zhang, Ivan Stoikov
Summary: New decasubstituted pillar[5]arene derivatives containing L-Tryptophan and L-Phenylalanine residues were synthesized as pH-responsive drug nanocarriers in this study. The experimental results showed that the derivative with L-Phenylalanine efficiently bound the fluorescent dye and had a higher rate of drug delivery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Hang Zhou, Wonyeong Jung, Tamanna Ishrat Farhana, Kazuya Fujimoto, Taeyoon Kim, Ryuji Yokokawa
Summary: Collective motion is a common phenomenon in nature, and it is mainly driven by dynamic collisions and alignments of cytoskeleton filaments. The study found that the persistence length of microtubules significantly affects their collective motion, with higher persistence leading to enhanced bundling. An agent-based computational model confirmed that the rigidity-dependent durability of microtubule alignment dominates their collective behavior.
Article
Dentistry, Oral Surgery & Medicine
W. Yan, C. Renteria, Y. Huang, Dwayne D. Arola
Summary: The study utilized unsupervised machine learning tools to investigate the relationship between composition and mechanical behavior of aging enamel, revealing positive correlation between hardness and elastic modulus with crystallinity, and negative correlation with carbonate substitution. The effects of fluoridation on enamel properties vary in different regions and ages.
Article
Plant Sciences
Yi-xin Lin, Hai-jin Xu, Guang-kun Yin, Yuan-chang Zhou, Xin-xiong Lu, Xia Xin
Summary: This study investigates the changes in membrane lipid components during seed aging and their impact on membrane function. The findings suggest that decreased antioxidant activity can lead to oxidative stress, resulting in increased membrane permeability and lipid peroxidation. The metabolism of phospholipids plays a key role in membrane metabolism during seed aging. The study also identifies specific lipid markers that could serve as potential indicators of soybean seed aging.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Wei Zhang, Jing-Jing Hu, Rui Liu, Jun Dai, Lizhen Yuan, Yiheng Liu, Bochao Chen, Mingxing Gong, Fan Xia, Xiaoding Lou
Summary: A smart transformable peptide-conjugated probe (DMFA) is designed for treatment on the tumor cell membrane, which undergoes in situ morphological transformation upon enzyme cleavage. The probe self-assembles into nanoparticles and anchors on the cell membrane, and upon cleavage by matrix metalloproteinase-2, it forms alpha-helix and beta-sheet structures. The resulting cell membrane breakage and nanofibers wrapping the cells can inhibit the PI3K-Akt signaling pathway, leading to the inhibition of tumor cell growth and metastasis. This peptide-conjugated probe shows great potential in tumor therapy.
Article
Biochemistry & Molecular Biology
Justin Amengual, Luke Notaro-Roberts, Mu -Ping Nieh
Summary: Bicellar systems have gained popularity in the fields of biochemistry, physical chemistry, and drug delivery technology due to their diverse morphology. They have been used as model membranes for studying transmembrane protein behavior and interactions with the cell. Additionally, they have shown potential as theranostic nanocarriers in biopharmaceutical and diagnostic research.
BIOPHYSICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Saqib Bilal, Taimoor Khan, Sajjad Asaf, Nasir Ali Khan, Syed Saad Jan, Muhammad Imran, Ahmed Al-Rawahi, Abdul Latif Khan, In-Jung Lee, Ahmed Al-Harrasi
Summary: Climate changes abruptly affect plant physiology and productivity. This study investigated the effects of low-temperature stress on date palm growth and physiological indicators with the application of silicon (Si). The application of Si improved plant morphology, biomass, photosynthetic pigments, and water content, while reducing oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Environmental
Zhangdi Li, Mei Gou, Xuejie Yue, Qiong Tian, Dongya Yang, Fengxian Qiu, Tao Zhang
Summary: The development of ZIF-L coated self-crosslinking cellulose membrane for tellurium adsorption presents a facile and cost-effective strategy. The membrane shows advantageous morphology of large contact surface, fine thermal stability, and eligible mechanical strength, making it a promising candidate for efficient tellurium adsorbents. Additionally, the ZIF-L/SC membrane has excellent antibacterial properties, showing potential in various fields in the future.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Qi Liu, Jingkang Wang, Xin Huang, Hao Wu, Shuyi Zong, Xiaowei Cheng, Hongxun Hao
Summary: This study investigates the role of water in molecular self-assembly. By using a microemulsion biomimetic system to simulate different water environments, the authors observed the formation of different crystal and fiber structures. The results suggest that different types of water trigger different nucleation and growth pathways.
Article
Engineering, Environmental
Mina Dolatshah, Ali Akbar Zinatizadeh, Sirus Zinadini, Hadis Zangeneh
Summary: In this study, two sets of superior hydrophilic nanofiltration membranes were prepared using a novel photocatalytic nanocomposite, leading to significant enhancement in membrane performance and antifouling properties. Evaluation showed improved filtration performance and great potential for practical application in water treatment for the modified membranes, especially those via the UV-grafting method.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Agriculture, Multidisciplinary
Eren Ozden
Summary: The deterioration of cellular membranes is a natural phenomenon in aging seeds. This study examined the physiological changes in aged cress seeds and seeds soaked under different temperatures after aging. The results showed that soaking increased the antioxidant capacity and reduced lipid peroxidation in aged seeds.
TURKISH JOURNAL OF AGRICULTURE AND FORESTRY
(2022)
Article
Geriatrics & Gerontology
Jitendra Kumar Arya, Raushan Kumar, Akanksha Singh, Parisha Srivastava, Arun Kumar Yadawa, Syed Ibrahim Rizvi
Summary: The study aimed to investigate the influence of acarbose on age-dependent deteriorated functions of erythrocyte membrane. The results showed that acarbose treatment effectively restored the activities of membrane-bound ATPases and the levels of redox biomarkers, as well as improved erythrocyte membrane osmotic fragility. These findings suggest that acarbose may have anti-aging effects.
REJUVENATION RESEARCH
(2023)
Article
Chemistry, Applied
Dibyendu Satapathi, Manik Das, Karunamoy Rajak, Soumik Laha, Md Maidul Islam, Indranil Choudhuri, Nandan Bhattacharyya, Sinjan Das, Bidhan Chandra Samanta, Tithi Maity
Summary: Two novel Cu(II) complexes and one Ni(II) complex have been developed and characterized for their structure and properties, including their binding ability with DNA and human serum albumin. Experimental methods and molecular docking studies confirmed the binding potential of these complexes with DNA and HSA, as well as their anticancer properties. The nuclear staining study revealed the nuclear morphological changes in cancer cells and suggested the activation of apoptotic pathways.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Meghna Ghosh, Sourav Nandi, Souvik Layek, Pratyush Kiran Nandi, Nanigopal Bera, Nilmoni Sarkar
Summary: Myo-inositol and its derivatives play a crucial role in cell biology, and interactions with model membranes can lead to the formation of lipid tubules, which can be prevented by using specific derivatives. Comparing these interactions with those of D-glucose, a proposed mechanism for the InOH-membrane interactions has been suggested.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Souvik Layek, Pavel Banerjee, Nilmoni Sarkar
Summary: This study investigates the interaction between solutes and an ionic liquid-DMSO mixture with varying levels of cellulose dissolution through fluorescence spectroscopic studies. The results indicate that the presence of cellulose modulates the dynamics of solutes in the mixture, leading to specific interaction patterns and temperature-dependent changes in rotational reorientation times. Overall, this work highlights the importance of understanding the photophysical aspects of cellulose dissolution in ionic liquid-DMSO mixtures.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Kishan Kumar Dakua, Karunamoy Rajak, Sabyashachi Mishra
Summary: The presence of excited electronic states near the optically bright state allows for various photo-relaxation channels. In transition-metal complexes, heavy atoms contribute to stronger spin-orbit coupling, enabling spin-forbidden processes to compete with spin-allowed processes. The distribution of these states is determined by the degree of vibronic coupling.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Biographical-Item
Chemistry, Physical
Nilmoni Sarkar, Nancy E. Levinger, Anindya Datta
JOURNAL OF PHYSICAL CHEMISTRY B
(2022)
Article
Chemistry, Multidisciplinary
Sourav Nandi, Anurup Mukhopadhyay, Pratyush Kiran Nandi, Nanigopal Bera, Ritwik Hazra, Jyotirmoy Chatterjee, Nilmoni Sarkar
Summary: The incorrect metabolism of amino acid methionine leads to hypermethioninemia, but the underlying mechanism is unknown. By studying a lipid membrane mimicking the cell membrane, it was found that methionine forms toxic aggregates that disrupt the rigidity of the membrane and increase its heterogeneity, resulting in deformation of red blood cells. Furthermore, the cross amyloids of methionine and phenylalanine were found to have the most virulent effect on the membrane bilayer and cytotoxicity.
Article
Biochemical Research Methods
Shakilur Rahman, Karunamoy Rajak, Sabyashachi Mishra, Amit Kumar Das
Summary: This study uses virtual screening and molecular simulations to identify drugs with potential inhibitory effects on Staphylococcus aureus FemX. Lumacaftor is found to be the most effective inhibitor.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2022)
Article
Chemistry, Physical
Susmita Das, Manik Das, Soumik Laha, Karunamoy Rajak, Indranil Choudhuri, Nandan Bhattacharyya, Bidhan Chandra Samanta, Tithi Maity
Summary: A Salen type Schiff base probe H3L was developed for selective and easy detection of Zn(II), Al(III), and SO4= ions. The probe exhibited moderate luminescent properties and showed fluorescence enhancement and diminution during the detection of Al(III)/Zn(II) and SO4=, respectively. The binding mechanisms between the probe and ions were analyzed through experimental and theoretical methods, and the probe was successfully applied for ion detection in tap water. Additionally, fluorescence live cell imaging study confirmed the effective sensing of intracellular Zn(II) by the chemosensor.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Meghna Ghosh, Souvik Layek, Nanigopal Bera, Pratyush Kiran Nandi, Ritwik Hazra, Nilmoni Sarkar
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Physical
Meghna Ghosh, Sanjukta Parida, Huma Khatoon, Nanigopal Bera, Sabyashachi Mishra, Nilmoni Sarkar
Summary: In this study, we investigated the ultrafast dynamics of fully deprotonated curcumin using time-resolved fluorescence spectroscopy. We found that the excited state photophysics of fully deprotonated curcumin is significantly different from that of neutral curcumin, with higher quantum yield, longer excited state lifetime, and slower solvation dynamics. The radiative decay of the fully deprotonated molecule is proposed to be associated with solvation dynamics and intramolecular charge transfer, while the possibility of excited state proton exchange or proton transfer is ruled out.
Article
Chemistry, Physical
Mrinmoy Mandal, Karunamoy Rajak, Biswajit Maiti
Summary: The reaction of atomic carbon with H(2)CO was studied using the direct dynamics trajectory surface hopping method. CH2+CO and H+HCCO were observed to be the major product channels. The insertion mechanism of the reaction is complex, with three different intermediates formed. A new product channel (H+HCCO-(X (2)A '')) was predicted through a head-on approach, contributing to approximately 46% of the overall products.
JOURNAL OF PHYSICAL CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Souvik Layek, Nanigopal Bera, Pratyush Kiran Nandi, Nilmoni Sarkar
Summary: In this study, it was discovered that THT exhibits strong emission in the presence of cellulose nanocrystals (CNCs). The emission properties of THT in aqueous CNC dispersion were investigated using steady-state and time-resolved emission techniques. The results showed that the lifetime of THT increased by approximately 1500 fold in the presence of CNCs compared to pure water (<1 ps). Stimuli-dependent and temperature-dependent studies suggested that electrostatic interaction is the main factor for the binding of THT with CNCs.
Article
Chemistry, Physical
Kishan Kumar Dakua, Karunamoy Rajak, Sabyashachi Mishra
Summary: This paper investigates the excited state dynamics of the thionated derivative of perylene diimides (PDIs), S2-PDI. The study reveals the population transfer from the (1)pp* state to the (3)pp* state through multiple pathways, including internal conversion and intersystem crossing. The calculated results agree well with experimental observations.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Nanigopal Bera, Souvik Layek, Shashwata Pramanik, Pratyush Kiran Nandi, Ritwik Hazra, Nilmoni Sarkar
Summary: This study reveals the ultrafast dynamics of the naturally occurring yellow polyphenolic medicinal pigment curcumin in the excited states, which is strongly influenced by the rigidity of the environments. The investigation also uncovers the ultrafast excited-state intramolecular hydrogen atom transfer (ESIHT) and solvation dynamics of curcumin in different self-assembled systems. Furthermore, a three-component fluorescence resonance energy transfer (Triple-FRET) system has been established to generate white light in micelles and giant vesicles.
Review
Chemistry, Multidisciplinary
Sourav Nandi, Nilmoni Sarkar
Summary: The rich photophysics of the ESIPT process in BP(OH)(2) system has attracted the interest of many researchers. There is controversy regarding the mechanism of this process, but recent studies have focused on the application of this probe in various organized assemblies.
JOURNAL OF CHEMICAL SCIENCES
(2022)