Journal
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
Volume 400, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jphotochem.2020.112701
Keywords
Formaldehyde; Fluorescent probe; Visual detection; Imaging
Categories
Funding
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
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As an important reactive carbonyl compound, formaldehyde (FA) existing in various parts of the organism and plays an important role in cognitive ability and memory formation. However, abnormal concentrations of FA could cause many diseases. Herein, a novel 1,8-naphthalimide derivative fluorescent probe (NID) for detecting FA was rationally designed and synthesized. Probe NID showed a rapid response (within 8 s) towards FA with visual detection. More importantly, NID can be used to image FA in MCF-7 cells, which demonstrated its suitability for practical applications of biological systems with low cytotoxicity.
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