Aqueous Dissolution and Dispersion Behavior of Polyvinylpyrrolidone Vinyl Acetate-based Amorphous Solid Dispersion of Ritonavir Prepared by Hot-Melt Extrusion with and without Added Surfactants

Title
Aqueous Dissolution and Dispersion Behavior of Polyvinylpyrrolidone Vinyl Acetate-based Amorphous Solid Dispersion of Ritonavir Prepared by Hot-Melt Extrusion with and without Added Surfactants
Authors
Keywords
Amorphous solid dispersion, Melt extrusion, Ritonavir, Polyvinylpyrrolidone vinyl acetate, Miscibility, Dissolution, Dispersion, Phase separation, Particle size, Stability
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-08-20
DOI
10.1016/j.xphs.2020.08.007

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