Journal
COORDINATION CHEMISTRY REVIEWS
Volume 324, Issue -, Pages 90-105Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2016.07.010
Keywords
Metal complexes; Protein biomarkers
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Funding
- Hong Kong Baptist University [FRG2/14-15/004, FRG2/15-16/002]
- Health and Medical Research Fund [HMRF/14130522]
- Research Grants Council [HKBU/201811, HKBU/204612, HKBU/201913]
- French Agence Nationale de la Recherche/Research Grants Council Joint Research Scheme [AHKBU201/12, Oligoswitch ANR-12-IS07-0001]
- National Natural Science Foundation of China [21575121]
- Guangdong Province Natural Science Foundation [2015A030313816]
- Hong Kong Baptist University Century Club Sponsorship Scheme
- Interdisciplinary Research Matching Scheme [RC-IRMS/14-15/06]
- Science and Technology Development Fund, Macau SAR [098/2014/A2]
- University of Macau [MYRG091(Y3-L2)-ICMS12-LCH, MYRG2015-00137-ICMS-QRCM MRG044/LCH/2015/ICMS]
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The detection of pathological biomarkers can allow for the early diagnosis and treatment of human disease, lowering morbidity and improving quality of life. Transition metal complexes have recently found use as luminescent probes for the detection of protein biomarkers. In this review, we highlight recent examples of metal complexes that have been used in DNA-based sensing platforms or as chemosensors for protein biomarkers. (C) 2016 Elsevier B.V. All rights reserved.
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