Down-regulation of SETD6 protects podocyte against high glucose and palmitic acid-induced apoptosis, and mitochondrial dysfunction via activating Nrf2-Keap1 signaling pathway in diabetic nephropathy

Telmisartan protects against high glucose/high lipid‐induced apoptosis and insulin secretion by reducing the oxidative and ER stress

(2019) Yan Wang et al.   CELL BIOCHEMISTRY AND FUNCTION

Moringa Isothiocyanate Activates Nrf2: Potential Role in Diabetic Nephropathy

(2019) David Cheng et al.   AAPS Journal

Metabolomics Reveal Altered Postprandial Lipid Metabolism After a High-Carbohydrate Meal in Men at High Genetic Risk of Diabetes

(2019) Edyta Adamska-Patruno et al.   JOURNAL OF NUTRITION

Sulfiredoxin-1 alleviates high glucose-induced podocyte injury though promoting Nrf2/ARE signaling via inactivation of GSK-3β

(2019) Yan Shen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Icariin modulates mitochondrial function and apoptosis in high glucose-induced glomerular podocytes through G protein-coupled estrogen receptors

(2018) Chen Qiao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Knockdown of TLR4 attenuates high glucose-induced podocyte injury via the NALP3/ASC/Caspase-1 signaling pathway

(2018) Yang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Carbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysis

(2018) Henny-Kristine Korsmo-Haugen et al.   DIABETES OBESITY & METABOLISM

SETD6 regulates NF-κB signaling in urothelial cell survival: Implications for bladder cancer

(2017) Neelam Mukherjee et al.   Oncotarget

SETD6 is a negative regulator of oxidative stress response

(2016) Ayelet Chen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/β-Catenin Pathway

(2016) Zlata Vershinin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

(2015) Atsuko Tagawa et al.   DIABETES

Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis

(2015) K. Sasaki et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification and comparison of gonadal transcripts of testis and ovary of adult common carp Cyprinus carpio using suppression subtractive hybridization

(2015) Jian-Jun Chen et al.   THERIOGENOLOGY

Activation of the Nrf2-ARE Pathway Attenuates Hyperglycemia-Mediated Injuries in Mouse Podocytes

(2014) Cheng Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vitamin D Activates the Nrf2-Keap1 Antioxidant Pathway and Ameliorates Nephropathy in Diabetic Rats

(2013) K. Nakai et al.   AMERICAN JOURNAL OF HYPERTENSION

NRF2 plays a protective role in diabetic retinopathy in mice

(2013) Zhenhua Xu et al.   DIABETOLOGIA

SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal

(2013) Olivier Binda et al.   Epigenetics

Changes of podocyte p130Cas in diabetic conditions

(2013) Tae-sun Ha et al.   JOURNAL OF NEPHROLOGY

Dysregulated Nephrin in Diabetic Nephropathy of Type 2 Diabetes: A Cross Sectional Study

(2012) Belinda Jim et al.   PLoS One

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Canonical Wnt/β-catenin signaling mediates transforming growth factor-β1-driven podocyte injury and proteinuria

(2011) Dan Wang et al.   KIDNEY INTERNATIONAL

Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling

(2011) Yanqi Chang et al.   NUCLEIC ACIDS RESEARCH

Pathogenesis of diabetic nephropathy

(2011) Zemin Cao et al.   Journal of Diabetes Investigation

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

(2010) L. M. Villeneuve et al.   DIABETES

Expression profiles of podocytes exposed to high glucose reveal new insights into early diabetic glomerulopathy

(2010) Sanjay Jain et al.   LABORATORY INVESTIGATION

Mechanisms of Podocyte Injury in Diabetes: Role of Cytochrome P450 and NADPH Oxidases

(2009) A. A. Eid et al.   DIABETES

Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions

(2009) Sang Choel Lee et al.   KIDNEY INTERNATIONAL

Proteinuria: an enzymatic disease of the podocyte?

(2009) Peter Mundel et al.   KIDNEY INTERNATIONAL