Article
Medicine, General & Internal
Johannes Rueckel, Nicola Fink, Sophia Kaestle, Theresa Stuber, Vincent Schwarze, Eva Gresser, Boj F. Hoppe, Jan Rudolph, Wolfgang G. Kunz, Jens Ricke, Bastian O. Sabel
Summary: Radiologists showed higher sensitivity and specificity in diagnosing COVID-19 compared to influenza based on CT imaging analysis, indicating the potential of CT for expedited patient management during the upcoming influenza season.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
Norman W. W. Baylor, Jesse L. L. Goodman
Summary: The response to SARS-CoV-2 demonstrated the potential of vaccine research and development, but there is still room for improvement in combating pandemics. This review focuses on enhancing research and evaluation processes and emphasizes the importance of moving vaccine development and evaluation to the pre-pandemic period.
Article
Public, Environmental & Occupational Health
Chon Fu Lio, Hou Hon Cheong, Chin Ion Lei, Iek Long Lo, Lan Yao, Chong Lam, Iek Hou Leong
Summary: Participating in high-risk gatherings, wearing a mask whenever outdoors, and practicing hand hygiene at key times should be advocated to the public to mitigate COVID-19 infection.
Review
Infectious Diseases
Lara Marleen Fricke, Stephan Glockner, Maren Dreier, Berit Lange
Summary: The study found that non-pharmaceutical interventions for COVID-19 have an impact on global influenza burden, leading to lower estimates of influenza. However, there is high heterogeneity in some indicators, such as unclear results for syndromic indicators.
JOURNAL OF INFECTION
(2021)
Article
Virology
Aylin O. Alpaydin, Naciye S. Gezer, Gokcen O. Simsek, Kemal C. Tertemiz, Oya O. E. Kutsoylu, Arzu N. Zeka, Irmak Guzel, Mujde Soyturk, Ayca A. Sayiner, Vildan A. Oguz
Summary: The study identified distinct clinical and laboratory features between COVID-19 and pneumonia caused by other viruses, but did not rule out the possibility of coinfections. Some clinical, laboratory, and radiological findings may assist in differentiating COVID-19 from other viral infections.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Review
Immunology
Dennis Kabantiyok, Nathaniel Ninyio, Ismaila Shittu, Clement Meseko, Theophilus Emeto, Oyelola A. Adegboye
Summary: The increasing outbreaks of zoonotic diseases pose challenges for nations and require efforts to disrupt the chain of infection. Nigeria has previous experience with influenza, but the emergence of SARS-CoV-2 provides new opportunities for vaccine development and co-infection studies. To prepare for the next pandemic, Nigeria and Africa should prioritize a combination of technology, socioeconomic growth, and active surveillance in line with the One Health approach.
Review
Environmental Sciences
Demian S. Barcellos, Carlos E. R. Barquilha, Pamela E. Oliveira, Mario Prokopiuk, Ramiro G. Etchepare
Summary: Wastewater-based epidemiology (WBE) has significantly developed during the COVID-19 pandemic, with widespread global application in monitoring the spread of the SARS-CoV-2 virus in urban communities. This mini-review examines the impact of the pandemic on WBE, based on the analysis of 1305 scientific reports. The findings demonstrate the migration of WBE's focus to studying the coronavirus and changes in research funding sources, collaborators, and study subjects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Public, Environmental & Occupational Health
Ivy Asantewaa Asante, Sharon Nienyun Hsu, Linda Boatemaa, Lorreta Kwasah, Mildred Adusei-Poku, John Kofi Odoom, Yaw Awuku-Larbi, Benjamin H. Foulkes, Joseph Oliver-Commey, Ernest Konadu Asiedu, Matthew D. Parker, Oriol Mitja, Rosalind M. Eggo, Leonardo de Oliveira-Martins, Franklin Asiedu-Bekoe, Dennis Odai Laryea, Patrick Kuma-Aboagye, Michael Marks, Thushan de Silva, William Kwabena Ampofo
Summary: This study integrated SARS-CoV-2 surveillance into an existing influenza surveillance network in Ghana, providing insights into the transmission and genomics of SARS-CoV-2. The study found co-circulation of influenza and SARS-CoV-2, as well as four waves of SARS-CoV-2 infections driven by different variants.
LANCET GLOBAL HEALTH
(2023)
Article
Geriatrics & Gerontology
Beata Jankowska-Polanska, Kathie Sarzynska, Aleksandra Pytel, Damian Izbianski, Dagmara Gawel-Dabrowska, Brygida Knysz
Summary: Poland is currently facing the second wave of the SARS-CoV-2 pandemic. Studies confirm that the mortality rate of COVID-19 increases with age. Preventing infections should be a priority for public health professionals. Evaluation of existing medical procedures in residential medical centers in Poland revealed gaps in knowledge about SARS-CoV-2 spread, which were addressed through training sessions and modifications to procedures.
Review
Chemistry, Medicinal
Evgeny Bazdyrev, Maria Panova, Valeria Zherebtsova, Alexandra Burdenkova, Ivan Grishagin, Fedor Novikov, Vladimir Nebolsin
Summary: This article discusses the epidemiology, pathogenesis, and clinical presentation of organizing pneumonia caused by COVID-19 and other viral infections. While oral corticosteroids have shown effectiveness in treating most patients with post-COVID-19 organizing pneumonia (PCOP), their use is limited due to high relapse rates and the risk of severe adverse effects. The article also explores the potential application of anti-inflammatory and antifibrotic therapy for the treatment of PCOP based on analysis of recent clinical trials data.
Article
Engineering, Environmental
Daniel Gerrity, Katerina Papp, Mitchell Stoker, Alan Sims, Wilbur Frehner
Summary: The study aimed to compare virus recovery and detection methods, detect and quantify SARS-CoV-2 genetic material in two sewersheds in Southern Nevada, and understand the link between COVID-19 incidence/prevalence and wastewater concentrations of SARS-CoV-2 RNA. Different methods and target water matrices led to varying virus recovery rates and sample volumes, impacting sensitivity and reported concentrations. Composite sampling showed a significant increase in concentration compared to grab samples, indicating diurnal variability in SARS-CoV-2 signal. Detection and quantification of genetic markers in sewage showed comparability with public health data in early pandemic stages.
Article
Infectious Diseases
Lisa Staadegaard, Marco Del Riccio, Sytske Wiegersma, Clotilde El Guerche-Seblain, Erica Dueger, Meral Akcay, Jean-Sebastien Casalegno, Michel Duckers, Saverio Caini, John Paget
Summary: The FluCov project, covering 22 countries, was initiated to monitor the impact of the SARS-CoV-2 pandemic on influenza activity. The survey results show the profound impact of SARS-CoV-2 on national influenza surveillance in the first 27 months of the pandemic. Most NICs were able to increase their laboratory testing capacity and the robustness of their surveillance systems, and anticipate the integration of SARS-CoV-2 surveillance into the existing respiratory surveillance system.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2023)
Article
Veterinary Sciences
Ana Judith Perise-Barrios, Beatriz Davinia Tomeo-Martin, Pablo Gomez-Ochoa, Pablo Delgado-Bonet, Pedro Plaza, Paula Palau-Concejo, Jorge Gonzalez, Gustavo Ortiz-Diez, Antonio Melendez-Lazo, Michaela Gentil, Javier Garcia-Castro, Alicia Barbero-Fernandez
Summary: The study found that dogs with alpha-SARS-CoV-2 IgG were not positive for SARS-CoV-2 RT-qPCR, even in those with severe pulmonary disease, suggesting low likelihood of transmission even in case of canine infection. Dogs living in COVID-19-positive households may have higher exposure to SARS-CoV-2 infection.
VETERINARY RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Varsha Potdar, Neetu Vijay, Labanya Mukhopadhyay, Neeraj Aggarwal, Sumit Dutt Bhardwaj, Manohar Lal Choudhary, Nivedita Gupta, Harmanmeet Kaur, Jitendra Narayan, Prabhat Kumar, Harpreet Singh, Rizwan Suliankatchi Abdulkader, Manoj Murhekar, Meena Mishra, Sundararajan Thangavel, K. Nagamani, Rahul Dhodapkar, Bashir Ahmad Fomda, Umesh Varshney, Agniva Majumdar, Shanta Dutta, P. Vijayachari, Jyotirmayee Turuk, Tapan Majumdar, Ganesh Chandra Sahoo, Krishna Pandey, Anudita Bhargava, Sanjay Singh Negi, Prabhat K. Khatri, Usha Kalawat, Debasis Biswas, Neeta Khandelwal, Biswajyoti Borkakoty, S. Manjushree, Mini P. Singh, Jyoti Iravane, K. Kaveri, G. B. Shantala, Megha Brijwal, Aashish Choudhary, Lalit Dar, Bharti Malhotra, Amita Jain, ILI SARI Surveillance Team
Summary: This study conducted surveillance for influenza and SARS-CoV-2 in India, revealing the changing strains and transmission dynamics of the viruses over time. The results emphasize the importance of expanding international surveillance and suggest the need to review the case definitions provided by WHO.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Public, Environmental & Occupational Health
Sazada Siddiqui, Heba Waheeb Saeed Alhamdi, Huda Ahmed Alghamdi
Summary: COVID-19 is highly contagious and has caused major disruptions around the world. Prevention is crucial through measures such as self-isolation and vaccination.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Immunology
Pei-Ru Yan, Hsin Chi, Nan-Chang Chiu, Ching-Ying Huang, Daniel Tsung-Ning Huang, Lung Chang, Yen-Hsin Kung, Fu-Yuan Huang, Chyong-Hsin Hsu, Jui-Hsing Chang, Hung -Yang Chang, Wai-Tim Jim
Summary: This study examined the effectiveness of prescribing antibiotics, particularly a single dose of vancomycin, in reducing the occurrence of sepsis with positive or negative cultures before the removal of peripherally inserted central catheters (PICCs). The results showed that a single prophylactic dose of vancomycin before PICC line removal may reduce the incidence of clinical sepsis events in infants.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Pediatrics
Ya-Ning Huang, Lu-Hang Liu, Jeng-Jung Chen, Yu-Lin Tai, Yih-Cherng Duh, Chien-Yu Lin
Summary: Kawasaki disease (KD) is a systemic inflammatory disease that can affect multiple organs. This case report highlights the atypical presentation of KD as appendicitis in a five-year-old boy. It emphasizes the importance of considering KD in children with abdominal complaints, especially those with persistent fever after appendectomy.
Editorial Material
Medicine, General & Internal
Yu-Lin Tai, Chien-Yu Lin
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Article
Pediatrics
Chien-Yu Lin, Shih-Yu Huang, Chuen-Bin Jiang, Chun-Chih Peng, Hsin Chi, Nan-Chang Chiu
Summary: This article reports a case of a 2-year-old boy with hand, foot, and mouth disease and severe complications. Timely diagnosis and management are crucial for successful management.
Article
Immunology
Shang -Chien Li, Hsin Chi, Fu-Yuan Huang, Nan-Chang Chiu, Ching-Ying Huang, Lung Chang, Yen-Hsin Kung, Pei-Fang Su, Yu-Lin Mau, Jin-Yuan Wang, Daniel Tsung-Ning Huang
Summary: This study aimed to formulate nomogram plots for clinicians to predict urinary tract infections (UTIs) in children aged <3 years by evaluating the risk factors. The study used a retrospective approach and analyzed children who underwent urine culture and urinalysis at a tertiary medical center from December 2017 to November 2020. The analysis identified significant factors and constructed nomogram plots for prediction in different medical settings.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2023)
Article
Virology
Ting-Hsuan Chen, Chung-Chu Chen, Suh-Chin Wu
Summary: The spatial organization of HA and NA on the virus surface needs to be optimized to promote viral fitness, host specificity, transmissibility, infectivity, and virulence. The viral NA enzyme activity increased for the RG pH1N1 (I365T/S366N) and RG pH1N1 (I365E/S366D) viruses but reduced for the RG pH1N1 (I365T/S366A) virus. All of these three NA 370-loop mutant RG pH1N1 viruses were less virulent than the wild-type RG pH1N1 virus in mice. Immunizations with the inactivated viruses carrying the three NA 370-loop mutations and the wild-type RG pH1N1 virus were found to elicit approximately the same titers of NA-inhibition antibodies against H1N1 and H5N1 viruses.
Article
Immunology
Ching-Ying Huang, Hsin Chi, Lung Chang, Nan -Chang Chiu
Summary: This study investigated the types, sizes, onset times, and durations of skin reactions in infants in Taiwan who received BCG vaccination at older than 5 months of age, and found that these infants had longer and more pronounced skin reactions compared to those vaccinated at birth.
Article
Pediatrics
Yuan-Hao Chang, Chien-Yu Lin, Lu-Hang Liu, Fu-Huan Huang, Yu-Jyun Cheng
Summary: Kawasaki disease shock syndrome (KDSS) is a severe form of Kawasaki disease (KD), characterized by hemodynamic instability and atypical manifestations. We report a case of an eight-year-old girl initially diagnosed with appendicitis, who developed KDSS after the surgery. With appropriate treatment, her symptoms resolved. We also reviewed two other cases of possible KDSS with appendicitis.
Article
Multidisciplinary Sciences
Yu -Lin Tai, Hsin Chi, Nan -Chang Chiu, Wei-Te Lei, Shun -Long Weng, Lawrence Yu -Min Liu, Chung -Chu Chen, Shih-Yu Huang, Ya-Ning Huang, Chien -Yu Lin
Summary: In this systematic review and meta-analysis, it was found that the use of bamlanivimab with or without etesevimab significantly reduced the risk of subsequent hospitalization and mortality in non-hospitalized COVID-19 patients. However, the emergence of resistant variants halted the clinical use of BAM/ETE.
Review
Biology
Ssu-Yu Chen, Chien-Yu Lin, Hsin Chi, Shun-Long Weng, Sung-Tse Li, Yu-Lin Tai, Ya-Ning Huang, Hsiang Huang, Chao-Hsu Lin, Nan-Chang Chiu
Summary: This study found that bivalent vaccines have similar immunogenicity against ancestral strains without safety concerns. They also show increased immunogenicity and clinical effectiveness against additional variant strains compared to monovalent vaccines.
Article
Medicine, General & Internal
Chao-Hsu Lin, Pei-Shun Lin, Meei-Shyuan Lee, Chien-Yu Lin, Yi-Hsiang Sung, Sung-Tse Li, Shun-Long Weng, Shing-Jyh Chang, Hung-Chang Lee, Yann-Jinn Lee, Hung-Yang Chang, Chih-Sheng Lin
Summary: This cross-sectional observation study examined the VD status and the effects of VD supplementation and macronutrient intake on serum 25(OH)D levels in Taiwanese pregnant women. The study found a high prevalence of VD deficiency in these women, and VD supplementation was the most effective method for increasing 25(OH)D concentration. Higher carbohydrate intake was associated with lower 25(OH)D levels.
MEDICINA-LITHUANIA
(2023)
Article
Pharmacology & Pharmacy
He-Chin Hsieh, Chung-Chu Chen, Pin-Han Chou, Wen-Chun Liu, Suh-Chin Wu
Summary: This preclinical study suggests that the RBD-LTA fusion protein could be a promising candidate as a mucosal booster COVID-19 vaccine, eliciting neutralizing antibodies against multiple SARS-CoV-2 variants and IgA antibodies in bronchoalveolar lavage fluids.
ANTIVIRAL RESEARCH
(2023)
