Mathematical models for the effect of anti-vascular endothelial growth factor on visual acuity

Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration

(2019) Kevin J. McHugh et al.   PLoS One

Optimizing Anti-VEGF Treatment Outcomes for Patients with Neovascular Age-Related Macular Degeneration

(2018) Charles C. Wykoff et al.   Journal of Managed Care & Specialty Pharmacy

Pharmacokinetics of intravitreal anti-VEGF drugs in vitrectomized versus non-vitrectomized eyes

(2017) Magdalena Edington et al.   Expert Opinion on Drug Metabolism & Toxicology

Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model

(2017) Laurence A. Hutton-Smith et al.   MOLECULAR PHARMACEUTICS

Pharmacokinetic aspects of retinal drug delivery

(2017) Eva M. del Amo et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Generative mathematical modelling to demonstrate virtual simulations of neovascular age related macular degeneration

(2017) David Hoyle et al.   PLoS One

A Computational Framework for Realistic Retina Modeling

(2016) Pablo Martínez-Cañada et al.   International Journal of Neural Systems

A Mechanistic Model of the Intravitreal Pharmacokinetics of Large Molecules and the Pharmacodynamic Suppression of Ocular Vascular Endothelial Growth Factor Levels by Ranibizumab in Patients with Neovascular Age-Related Macular Degeneration

(2016) Laurence A. Hutton-Smith et al.   MOLECULAR PHARMACEUTICS

Mathematical and computational models of the retina in health, development and disease

(2016) Paul A. Roberts et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Pharmacokinetic and Pharmacodynamic Properties of Anti-VEGF Drugs After Intravitreal Injection

(2015) Francesco Semeraro et al.   CURRENT DRUG METABOLISM

The PK-Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development

(2015) Sahar Awwad et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA)

(2014) Ursula Schmidt-Erfurth et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Virtual pharmacokinetic model of human eye

(2014) Sreevani Kotha et al.   MATHEMATICAL BIOSCIENCES