Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration

Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

(2019) Takeshi Suetomi et al.   CIRCULATION

The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM

(2019) Melanie H. Wong et al.   JOURNAL OF MOLECULAR BIOLOGY

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

(2019) David P. Sullivan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endothelial Cell Calcium Signaling during Barrier Function and Inflammation

(2019) Prarthana J. Dalal et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration

(2017) Jian Song et al.   Cell Reports

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity

(2017) Shubha Murthy et al.   PLoS One

A Unique Role for Endothelial Cell Kinesin Light Chain 1, Variant 1 in Leukocyte Transendothelial Migration

(2016) Bita F. Cyrus et al.   AMERICAN JOURNAL OF PATHOLOGY

4D intravital microscopy uncovers critical strain differences for the roles of PECAM and CD99 in leukocyte diapedesis

(2016) David P. Sullivan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Localized signals that regulate transendothelial migration

(2016) William A Muller   CURRENT OPINION IN IMMUNOLOGY

Transendothelial migration: unifying principles from the endothelial perspective

(2016) William A. Muller   IMMUNOLOGICAL REVIEWS

F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling

(2016) Niels Heemskerk et al.   Nature Communications

Blunted mGluR Activation Disinhibits Striatopallidal Transmission in Parkinsonian Mice

(2016) Qiaoling Cui et al.   Cell Reports

The biology of IQGAP proteins: beyond the cytoskeleton

(2015) A. C. Hedman et al.   EMBO REPORTS

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration

(2015) Richard L. Watson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response

(2015) Evan W. Weber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes

(2015) Anja Hasenberg et al.   NATURE METHODS

Leukocyte Migration into Inflamed Tissues

(2014) Sussan Nourshargh et al.   IMMUNITY

Isolation of the Lateral Border Recycling Compartment Using a Diaminobenzidine-Induced Density Shift

(2014) David P. Sullivan et al.   TRAFFIC

CaMKII inhibitors: from research tools to therapeutic agents

(2014) Patricia Pellicena et al.   Frontiers in Pharmacology

Poliovirus Receptor (CD155) Regulates a Step in Transendothelial Migration between PECAM and CD99

(2013) David P. Sullivan et al.   AMERICAN JOURNAL OF PATHOLOGY

Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Mediates Myocardial Ischemia/Reperfusion Injury Through Nuclear Factor-κB

(2013) Haiyun Ling et al.   CIRCULATION RESEARCH

Contrasting Roles of E2F2 and E2F3 in Cardiac Neovascularization

(2013) Junlan Zhou et al.   PLoS One

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

(2012) Doris Proebstl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Mechanisms of Leukocyte Transendothelial Migration

(2011) William A. Muller   Annual Review of Pathology-Mechanisms of Disease

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

(2011) Luke H. Chao et al.   CELL

Characterization of novel calmodulin binding domains within IQ motifs of IQGAP1

(2011) Deok-Jin Jang et al.   MOLECULES AND CELLS

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

(2011) Abigail Woodfin et al.   NATURE IMMUNOLOGY

Ca2+/Calmodulin-dependent Protein Kinase II Inhibitors Disrupt AKAP79-dependent PKC Signaling to GluA1 AMPA Receptors

(2010) Ian M. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium/Calmodulin-dependent Protein Kinase II Delta 6 (CaMKIIδ6) and RhoA Involvement in Thrombin-induced Endothelial Barrier Dysfunction

(2010) Zhen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Genetically encoded biosensors based on engineered fluorescent proteins

(2009) Wolf B. Frommer et al.   CHEMICAL SOCIETY REVIEWS

Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

(2009) Haiyun Ling et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment

(2009) Zahra Mamdouh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design

(2008) Jasper Akerboom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment

(2008) Zahra Mamdouh et al.   JOURNAL OF EXPERIMENTAL MEDICINE